Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MDA-MB-415 | HR+ | Luminal | Glycyl-H-1152 | ROCK2 | 0.107 | uM | 12333.169 | 1.0220 | 1.0801 | 0.5536 | ||
| MDA-MB-415 | HR+ | Luminal | Glycyl-H-1152 | ROCK2 | 0.533 | uM | 12333.169 | 1.0330 | 1.1209 | 0.5536 | ||
| MDA-MB-415 | HR+ | Luminal | Glycyl-H-1152 | ROCK2 | 2.67 | uM | 12333.169 | 0.7259 | 0.1214 | 0.5536 | ||
| MDA-MB-415 | HR+ | Luminal | Glycyl-H-1152 | ROCK2 | 13.3 | uM | 12333.169 | 0.8140 | 0.3790 | 0.5536 | ||
| MDA-MB-415 | HR+ | Luminal | Glycyl-H-1152 | ROCK2 | 66.7 | uM | 12333.169 | 0.7398 | 0.1604 | 0.5536 | ||
| MDA-MB-453 | TNBC | Luminal | Glycyl-H-1152 | ROCK2 | 0.000171 | uM | 12414.169 | 0.9812 | 0.9665 | 1.1235 | ||
| MDA-MB-453 | TNBC | Luminal | Glycyl-H-1152 | ROCK2 | 0.000853 | uM | 12414.169 | 0.9805 | 0.9652 | 1.1235 | ||
| MDA-MB-453 | TNBC | Luminal | Glycyl-H-1152 | ROCK2 | 0.00427 | uM | 12414.169 | 0.9206 | 0.8580 | 1.1235 | ||
| MDA-MB-453 | TNBC | Luminal | Glycyl-H-1152 | ROCK2 | 0.0213 | uM | 12414.169 | 0.8908 | 0.8045 | 1.1235 | ||
| MDA-MB-453 | TNBC | Luminal | Glycyl-H-1152 | ROCK2 | 0.107 | uM | 12414.169 | 0.9584 | 0.9257 | 1.1235 | ||
| MDA-MB-453 | TNBC | Luminal | Glycyl-H-1152 | ROCK2 | 0.533 | uM | 12414.169 | 0.9979 | 0.9963 | 1.1235 | ||
| MDA-MB-453 | TNBC | Luminal | Glycyl-H-1152 | ROCK2 | 2.67 | uM | 12414.169 | 0.8242 | 0.6838 | 1.1235 | ||
| MDA-MB-453 | TNBC | Luminal | Glycyl-H-1152 | ROCK2 | 13.3 | uM | 12414.169 | 0.7954 | 0.6313 | 1.1235 | ||
| MDA-MB-453 | TNBC | Luminal | Glycyl-H-1152 | ROCK2 | 66.7 | uM | 12414.169 | 0.6461 | 0.3558 | 1.1235 | ||
| MX1 | Unknown | Unknown | Glycyl-H-1152 | ROCK2 | 0.0000853 | uM | 10644.138 | 1.0563 | 1.2046 | 0.5624 | ||
| MX1 | Unknown | Unknown | Glycyl-H-1152 | ROCK2 | 0.000427 | uM | 10644.138 | 0.9174 | 0.7156 | 0.5624 | ||
| MX1 | Unknown | Unknown | Glycyl-H-1152 | ROCK2 | 0.00213 | uM | 10644.138 | 1.0098 | 1.0350 | 0.5624 | ||
| MX1 | Unknown | Unknown | Glycyl-H-1152 | ROCK2 | 0.0107 | uM | 10644.138 | 0.9521 | 0.8330 | 0.5624 | ||
| MX1 | Unknown | Unknown | Glycyl-H-1152 | ROCK2 | 0.0533 | uM | 10644.138 | 0.9969 | 0.9889 | 0.5624 | ||
| MX1 | Unknown | Unknown | Glycyl-H-1152 | ROCK2 | 0.267 | uM | 10644.138 | 0.9993 | 0.9976 | 0.5624 | ||
| MX1 | Unknown | Unknown | Glycyl-H-1152 | ROCK2 | 1.33 | uM | 10644.138 | 0.5821 | -0.2359 | 0.5624 | ||
| MX1 | Unknown | Unknown | Glycyl-H-1152 | ROCK2 | 6.67 | uM | 10644.138 | 0.2770 | -0.7960 | 0.5624 | ||
| MX1 | Unknown | Unknown | Glycyl-H-1152 | ROCK2 | 33.3 | uM | 10644.138 | 0.1370 | -0.9417 | 0.5624 | ||
| MX1 | Unknown | Unknown | Glycyl-H-1152 | ROCK2 | 0.0000853 | uM | 10874.15 | 0.9141 | 0.8127 | 0.9133 | ||
| MX1 | Unknown | Unknown | Glycyl-H-1152 | ROCK2 | 0.000427 | uM | 10874.15 | 0.9179 | 0.8209 | 0.9133 |