Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC2185 | TNBC | Luminal | Glycyl-H-1152 | ROCK2 | 1.33 | uM | 10996.15 | 0.8332 | 0.3977 | 0.5092 | ||
| HCC2185 | TNBC | Luminal | Glycyl-H-1152 | ROCK2 | 6.67 | uM | 10996.15 | 0.7594 | 0.1650 | 0.5092 | ||
| HCC2185 | TNBC | Luminal | Glycyl-H-1152 | ROCK2 | 33.3 | uM | 10996.15 | 0.6862 | -0.0454 | 0.5092 | ||
| HCC2185 | TNBC | Luminal | Glycyl-H-1152 | ROCK2 | 0.000171 | uM | 12192.16 | 0.9478 | 0.8595 | 0.7363 | ||
| HCC2185 | TNBC | Luminal | Glycyl-H-1152 | ROCK2 | 0.000853 | uM | 12192.16 | 1.0666 | 1.1830 | 0.7363 | ||
| HCC2185 | TNBC | Luminal | Glycyl-H-1152 | ROCK2 | 0.00427 | uM | 12192.16 | 0.9771 | 0.9379 | 0.7363 | ||
| HCC2185 | TNBC | Luminal | Glycyl-H-1152 | ROCK2 | 0.0213 | uM | 12192.16 | 1.0346 | 1.0945 | 0.7363 | ||
| HCC2185 | TNBC | Luminal | Glycyl-H-1152 | ROCK2 | 0.107 | uM | 12192.16 | 0.9035 | 0.7424 | 0.7363 | ||
| HCC2185 | TNBC | Luminal | Glycyl-H-1152 | ROCK2 | 0.533 | uM | 12192.16 | 1.0123 | 1.0334 | 0.7363 | ||
| HCC2185 | TNBC | Luminal | Glycyl-H-1152 | ROCK2 | 2.67 | uM | 12192.16 | 0.8321 | 0.5582 | 0.7363 | ||
| HCC2185 | TNBC | Luminal | Glycyl-H-1152 | ROCK2 | 13.3 | uM | 12192.16 | 0.6627 | 0.1437 | 0.7363 | ||
| HCC2185 | TNBC | Luminal | Glycyl-H-1152 | ROCK2 | 66.7 | uM | 12192.16 | 0.5354 | -0.1440 | 0.7363 | ||
| HCC3153 | TNBC | Basal A | Glycyl-H-1152 | ROCK2 | 0.0000853 | uM | 10577.138 | 1.0256 | 1.0493 | 1.0408 | ||
| HCC3153 | TNBC | Basal A | Glycyl-H-1152 | ROCK2 | 0.000427 | uM | 10577.138 | 0.9901 | 0.9811 | 1.0408 | ||
| HCC3153 | TNBC | Basal A | Glycyl-H-1152 | ROCK2 | 0.00213 | uM | 10577.138 | 1.0177 | 1.0341 | 1.0408 | ||
| HCC3153 | TNBC | Basal A | Glycyl-H-1152 | ROCK2 | 0.0107 | uM | 10577.138 | 0.9750 | 0.9519 | 1.0408 | ||
| HCC3153 | TNBC | Basal A | Glycyl-H-1152 | ROCK2 | 0.0533 | uM | 10577.138 | 0.9628 | 0.9285 | 1.0408 | ||
| HCC3153 | TNBC | Basal A | Glycyl-H-1152 | ROCK2 | 0.267 | uM | 10577.138 | 1.0189 | 1.0364 | 1.0408 | ||
| HCC3153 | TNBC | Basal A | Glycyl-H-1152 | ROCK2 | 1.33 | uM | 10577.138 | 0.9258 | 0.8572 | 1.0408 | ||
| HCC3153 | TNBC | Basal A | Glycyl-H-1152 | ROCK2 | 6.67 | uM | 10577.138 | 0.9551 | 0.9137 | 1.0408 | ||
| HCC3153 | TNBC | Basal A | Glycyl-H-1152 | ROCK2 | 33.3 | uM | 10577.138 | 0.9388 | 0.8823 | 1.0408 | ||
| HCC3153 | TNBC | Basal A | Glycyl-H-1152 | ROCK2 | 0.0000853 | uM | 10937.15 | 0.9749 | 0.9633 | 1.3769 | ||
| HCC3153 | TNBC | Basal A | Glycyl-H-1152 | ROCK2 | 0.000427 | uM | 10937.15 | 1.0293 | 1.0425 | 1.3769 | ||
| HCC3153 | TNBC | Basal A | Glycyl-H-1152 | ROCK2 | 0.00213 | uM | 10937.15 | 0.9774 | 0.9671 | 1.3769 | ||
| HCC3153 | TNBC | Basal A | Glycyl-H-1152 | ROCK2 | 0.0107 | uM | 10937.15 | 1.0241 | 1.0348 | 1.3769 |