Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 184A1 | NM | Basal | Glycyl-H-1152 | ROCK2 | 66.7 | uM | 12509.169 | 0.9125 | 0.8820 | 1.5064 | ||
| 184B5 | NM | Basal | Glycyl-H-1152 | ROCK2 | 0.000171 | uM | 12566.169 | 1.0194 | 1.0236 | 1.6359 | ||
| 184B5 | NM | Basal | Glycyl-H-1152 | ROCK2 | 0.000853 | uM | 12566.169 | 0.9459 | 0.9331 | 1.6359 | ||
| 184B5 | NM | Basal | Glycyl-H-1152 | ROCK2 | 0.00427 | uM | 12566.169 | 0.9951 | 0.9940 | 1.6359 | ||
| 184B5 | NM | Basal | Glycyl-H-1152 | ROCK2 | 0.0213 | uM | 12566.169 | 0.9278 | 0.9104 | 1.6359 | ||
| 184B5 | NM | Basal | Glycyl-H-1152 | ROCK2 | 0.107 | uM | 12566.169 | 0.9941 | 0.9928 | 1.6359 | ||
| 184B5 | NM | Basal | Glycyl-H-1152 | ROCK2 | 0.533 | uM | 12566.169 | 0.9095 | 0.8874 | 1.6359 | ||
| 184B5 | NM | Basal | Glycyl-H-1152 | ROCK2 | 2.67 | uM | 12566.169 | 0.8605 | 0.8246 | 1.6359 | ||
| 184B5 | NM | Basal | Glycyl-H-1152 | ROCK2 | 13.3 | uM | 12566.169 | 0.8481 | 0.8083 | 1.6359 | ||
| 184B5 | NM | Basal | Glycyl-H-1152 | ROCK2 | 66.7 | uM | 12566.169 | 0.6878 | 0.5910 | 1.6359 | ||
| 600MPE | HR+ | Luminal | Glycyl-H-1152 | ROCK2 | 0.000171 | uM | 12224.16 | 1.0067 | 1.0174 | 0.7734 | ||
| 600MPE | HR+ | Luminal | Glycyl-H-1152 | ROCK2 | 0.000853 | uM | 12224.16 | 0.9496 | 0.8706 | 0.7734 | ||
| 600MPE | HR+ | Luminal | Glycyl-H-1152 | ROCK2 | 0.00427 | uM | 12224.16 | 0.9781 | 0.9435 | 0.7734 | ||
| 600MPE | HR+ | Luminal | Glycyl-H-1152 | ROCK2 | 0.0213 | uM | 12224.16 | 0.9445 | 0.8576 | 0.7734 | ||
| 600MPE | HR+ | Luminal | Glycyl-H-1152 | ROCK2 | 0.107 | uM | 12224.16 | 0.9947 | 0.9864 | 0.7734 | ||
| 600MPE | HR+ | Luminal | Glycyl-H-1152 | ROCK2 | 0.533 | uM | 12224.16 | 0.9895 | 0.9729 | 0.7734 | ||
| 600MPE | HR+ | Luminal | Glycyl-H-1152 | ROCK2 | 2.67 | uM | 12224.16 | 0.9379 | 0.8409 | 0.7734 | ||
| 600MPE | HR+ | Luminal | Glycyl-H-1152 | ROCK2 | 13.3 | uM | 12224.16 | 0.9895 | 0.9729 | 0.7734 | ||
| 600MPE | HR+ | Luminal | Glycyl-H-1152 | ROCK2 | 66.7 | uM | 12224.16 | 0.9973 | 0.9930 | 0.7734 | ||
| AU565 | HER2amp | Luminal | Glycyl-H-1152 | ROCK2 | 0.0000853 | uM | 10880.15 | 0.9870 | 0.9836 | 1.5829 | ||
| AU565 | HER2amp | Luminal | Glycyl-H-1152 | ROCK2 | 0.000427 | uM | 10880.15 | 0.9481 | 0.9337 | 1.5829 | ||
| AU565 | HER2amp | Luminal | Glycyl-H-1152 | ROCK2 | 0.00213 | uM | 10880.15 | 0.9716 | 0.9639 | 1.5829 | ||
| AU565 | HER2amp | Luminal | Glycyl-H-1152 | ROCK2 | 0.0107 | uM | 10880.15 | 0.9672 | 0.9583 | 1.5829 | ||
| AU565 | HER2amp | Luminal | Glycyl-H-1152 | ROCK2 | 0.0533 | uM | 10880.15 | 0.9564 | 0.9445 | 1.5829 | ||
| AU565 | HER2amp | Luminal | Glycyl-H-1152 | ROCK2 | 0.267 | uM | 10880.15 | 0.9633 | 0.9533 | 1.5829 |