Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MDA-MB-468 | TNBC | Basal A | Gemcitabine | DNA replication | DNA replication | 0.00185 | uM | 7905.011 | 0.7374 | 0.4292 | 0.9066 | |
| MDA-MB-468 | TNBC | Basal A | Gemcitabine | DNA replication | DNA replication | 0.00925 | uM | 7905.011 | 1.0211 | 1.0466 | 0.9066 | |
| MDA-MB-468 | TNBC | Basal A | Gemcitabine | DNA replication | DNA replication | 0.0462 | uM | 7905.011 | 0.8963 | 0.7725 | 0.9066 | |
| MDA-MB-468 | TNBC | Basal A | Gemcitabine | DNA replication | DNA replication | 0.231 | uM | 7905.011 | 0.9191 | 0.8222 | 0.9066 | |
| MDA-MB-468 | TNBC | Basal A | Gemcitabine | DNA replication | DNA replication | 1.16 | uM | 7905.011 | 0.7489 | 0.4540 | 0.9066 | |
| MDA-MB-468 | TNBC | Basal A | Gemcitabine | DNA replication | DNA replication | 5.78 | uM | 7905.011 | 0.7665 | 0.4916 | 0.9066 | |
| MDA-MB-468 | TNBC | Basal A | Gemcitabine | DNA replication | DNA replication | 28.9 | uM | 7905.011 | 0.7896 | 0.5412 | 0.9066 | |
| MDA-MB-468 | TNBC | Basal A | Gemcitabine | DNA replication | DNA replication | 144 | uM | 7905.011 | 0.5403 | 0.0141 | 0.9066 | |
| MDA-MB-468 | TNBC | Basal A | Gemcitabine | DNA replication | DNA replication | 0.00037 | uM | 7906.011 | 0.8262 | 0.5672 | 0.7830 | |
| MDA-MB-468 | TNBC | Basal A | Gemcitabine | DNA replication | DNA replication | 0.00185 | uM | 7906.011 | 1.0911 | 1.2356 | 0.7830 | |
| MDA-MB-468 | TNBC | Basal A | Gemcitabine | DNA replication | DNA replication | 0.00925 | uM | 7906.011 | 1.4237 | 2.1403 | 0.7830 | |
| MDA-MB-468 | TNBC | Basal A | Gemcitabine | DNA replication | DNA replication | 0.0462 | uM | 7906.011 | 0.9070 | 0.7657 | 0.7830 | |
| MDA-MB-468 | TNBC | Basal A | Gemcitabine | DNA replication | DNA replication | 0.231 | uM | 7906.011 | 1.0659 | 1.1699 | 0.7830 | |
| MDA-MB-468 | TNBC | Basal A | Gemcitabine | DNA replication | DNA replication | 1.16 | uM | 7906.011 | 0.6234 | 0.0937 | 0.7830 | |
| MDA-MB-468 | TNBC | Basal A | Gemcitabine | DNA replication | DNA replication | 5.78 | uM | 7906.011 | 0.8847 | 0.7103 | 0.7830 | |
| MDA-MB-468 | TNBC | Basal A | Gemcitabine | DNA replication | DNA replication | 28.9 | uM | 7906.011 | 0.7077 | 0.2862 | 0.7830 | |
| MDA-MB-468 | TNBC | Basal A | Gemcitabine | DNA replication | DNA replication | 144 | uM | 7906.011 | 0.4982 | -0.1786 | 0.7830 | |
| MDA-MB-468 | TNBC | Basal A | Gemcitabine | DNA replication | DNA replication | 0.00037 | uM | 7907.011 | 1.2356 | 1.3233 | 1.4119 | |
| MDA-MB-468 | TNBC | Basal A | Gemcitabine | DNA replication | DNA replication | 0.00185 | uM | 7907.011 | 0.8199 | 0.7375 | 1.4119 | |
| MDA-MB-468 | TNBC | Basal A | Gemcitabine | DNA replication | DNA replication | 0.00925 | uM | 7907.011 | 1.2546 | 1.3486 | 1.4119 | |
| MDA-MB-468 | TNBC | Basal A | Gemcitabine | DNA replication | DNA replication | 0.0462 | uM | 7907.011 | 0.7413 | 0.6179 | 1.4119 | |
| MDA-MB-468 | TNBC | Basal A | Gemcitabine | DNA replication | DNA replication | 0.231 | uM | 7907.011 | 0.7473 | 0.6272 | 1.4119 | |
| MDA-MB-468 | TNBC | Basal A | Gemcitabine | DNA replication | DNA replication | 1.16 | uM | 7907.011 | 0.6927 | 0.5420 | 1.4119 | |
| MDA-MB-468 | TNBC | Basal A | Gemcitabine | DNA replication | DNA replication | 5.78 | uM | 7907.011 | 0.6990 | 0.5520 | 1.4119 | |
| MDA-MB-468 | TNBC | Basal A | Gemcitabine | DNA replication | DNA replication | 28.9 | uM | 7907.011 | 0.7666 | 0.6568 | 1.4119 |