Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MDA-MB-453 | TNBC | Luminal | Gemcitabine | DNA replication | DNA replication | 0.0462 | uM | 7903.011 | 0.3057 | -0.2841 | 1.1535 | |
| MDA-MB-453 | TNBC | Luminal | Gemcitabine | DNA replication | DNA replication | 0.231 | uM | 7903.011 | 0.3094 | -0.2767 | 1.1535 | |
| MDA-MB-453 | TNBC | Luminal | Gemcitabine | DNA replication | DNA replication | 1.16 | uM | 7903.011 | 0.3348 | -0.2255 | 1.1535 | |
| MDA-MB-453 | TNBC | Luminal | Gemcitabine | DNA replication | DNA replication | 5.78 | uM | 7903.011 | 0.3437 | -0.2076 | 1.1535 | |
| MDA-MB-453 | TNBC | Luminal | Gemcitabine | DNA replication | DNA replication | 28.9 | uM | 7903.011 | 0.3105 | -0.2745 | 1.1535 | |
| MDA-MB-453 | TNBC | Luminal | Gemcitabine | DNA replication | DNA replication | 144 | uM | 7903.011 | 0.2807 | -0.3351 | 1.1535 | |
| MDA-MB-453 | TNBC | Luminal | Gemcitabine | DNA replication | DNA replication | 0.00037 | uM | 9708.011 | 1.0579 | 1.1097 | 1.0535 | |
| MDA-MB-453 | TNBC | Luminal | Gemcitabine | DNA replication | DNA replication | 0.00185 | uM | 9708.011 | 1.0493 | 1.0935 | 1.0535 | |
| MDA-MB-453 | TNBC | Luminal | Gemcitabine | DNA replication | DNA replication | 0.00925 | uM | 9708.011 | 0.7991 | 0.6165 | 1.0535 | |
| MDA-MB-453 | TNBC | Luminal | Gemcitabine | DNA replication | DNA replication | 0.0462 | uM | 9708.011 | 0.5668 | 0.1667 | 1.0535 | |
| MDA-MB-453 | TNBC | Luminal | Gemcitabine | DNA replication | DNA replication | 0.231 | uM | 9708.011 | 0.5547 | 0.1431 | 1.0535 | |
| MDA-MB-453 | TNBC | Luminal | Gemcitabine | DNA replication | DNA replication | 1.16 | uM | 9708.011 | 0.5106 | 0.0566 | 1.0535 | |
| MDA-MB-453 | TNBC | Luminal | Gemcitabine | DNA replication | DNA replication | 5.78 | uM | 9708.011 | 0.5002 | 0.0363 | 1.0535 | |
| MDA-MB-453 | TNBC | Luminal | Gemcitabine | DNA replication | DNA replication | 28.9 | uM | 9708.011 | 0.4802 | -0.0032 | 1.0535 | |
| MDA-MB-453 | TNBC | Luminal | Gemcitabine | DNA replication | DNA replication | 144 | uM | 9708.011 | 0.4904 | 0.0170 | 1.0535 | |
| MDA-MB-453 | TNBC | Luminal | Gemcitabine | DNA replication | DNA replication | 0.000168 | uM | 9723.12 | 1.1377 | 1.3303 | 0.8437 | |
| MDA-MB-453 | TNBC | Luminal | Gemcitabine | DNA replication | DNA replication | 0.00084 | uM | 9723.12 | 1.0040 | 1.0095 | 0.8437 | |
| MDA-MB-453 | TNBC | Luminal | Gemcitabine | DNA replication | DNA replication | 0.0042 | uM | 9723.12 | 1.1332 | 1.3195 | 0.8437 | |
| MDA-MB-453 | TNBC | Luminal | Gemcitabine | DNA replication | DNA replication | 0.021 | uM | 9723.12 | 0.6495 | 0.1992 | 0.8437 | |
| MDA-MB-453 | TNBC | Luminal | Gemcitabine | DNA replication | DNA replication | 0.105 | uM | 9723.12 | 0.4850 | -0.1517 | 0.8437 | |
| MDA-MB-453 | TNBC | Luminal | Gemcitabine | DNA replication | DNA replication | 0.525 | uM | 9723.12 | 0.5446 | -0.0268 | 0.8437 | |
| MDA-MB-453 | TNBC | Luminal | Gemcitabine | DNA replication | DNA replication | 2.62 | uM | 9723.12 | 0.5673 | 0.0215 | 0.8437 | |
| MDA-MB-453 | TNBC | Luminal | Gemcitabine | DNA replication | DNA replication | 13.1 | uM | 9723.12 | 0.4973 | -0.1261 | 0.8437 | |
| MDA-MB-453 | TNBC | Luminal | Gemcitabine | DNA replication | DNA replication | 65.6 | uM | 9723.12 | 0.4663 | -0.1903 | 0.8437 | |
| MDA-MB-468 | TNBC | Basal A | Gemcitabine | DNA replication | DNA replication | 0.00037 | uM | 7905.011 | 0.9997 | 0.9994 | 0.9066 |