Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HMT-3522 S1 | Unknown | Unknown | Gemcitabine | DNA replication | DNA replication | 1.16 | uM | 7911.011 | 0.4877 | 0.2822 | 1.6150 | |
| HMT-3522 S1 | Unknown | Unknown | Gemcitabine | DNA replication | DNA replication | 5.78 | uM | 7911.011 | 0.3941 | 0.1236 | 1.6150 | |
| HMT-3522 S1 | Unknown | Unknown | Gemcitabine | DNA replication | DNA replication | 28.9 | uM | 7911.011 | 0.3606 | 0.0634 | 1.6150 | |
| HMT-3522 S1 | Unknown | Unknown | Gemcitabine | DNA replication | DNA replication | 144 | uM | 7911.011 | 0.3721 | 0.0844 | 1.6150 | |
| Hs 578T | TNBC | Basal B | Gemcitabine | DNA replication | DNA replication | 0.00037 | uM | 7862.011 | 0.9057 | 0.8604 | 1.3695 | |
| Hs 578T | TNBC | Basal B | Gemcitabine | DNA replication | DNA replication | 0.00185 | uM | 7862.011 | 1.0391 | 1.0568 | 1.3695 | |
| Hs 578T | TNBC | Basal B | Gemcitabine | DNA replication | DNA replication | 0.00925 | uM | 7862.011 | 0.8900 | 0.8368 | 1.3695 | |
| Hs 578T | TNBC | Basal B | Gemcitabine | DNA replication | DNA replication | 0.0462 | uM | 7862.011 | 0.7696 | 0.6519 | 1.3695 | |
| Hs 578T | TNBC | Basal B | Gemcitabine | DNA replication | DNA replication | 0.231 | uM | 7862.011 | 0.4537 | 0.1230 | 1.3695 | |
| Hs 578T | TNBC | Basal B | Gemcitabine | DNA replication | DNA replication | 1.16 | uM | 7862.011 | 0.5293 | 0.2568 | 1.3695 | |
| Hs 578T | TNBC | Basal B | Gemcitabine | DNA replication | DNA replication | 5.78 | uM | 7862.011 | 0.4523 | 0.1206 | 1.3695 | |
| Hs 578T | TNBC | Basal B | Gemcitabine | DNA replication | DNA replication | 28.9 | uM | 7862.011 | 0.4362 | 0.0913 | 1.3695 | |
| Hs 578T | TNBC | Basal B | Gemcitabine | DNA replication | DNA replication | 144 | uM | 7862.011 | 0.4611 | 0.1364 | 1.3695 | |
| Hs 578T | TNBC | Basal B | Gemcitabine | DNA replication | DNA replication | 0.00037 | uM | 7863.011 | 0.9676 | 0.9677 | 2.0237 | |
| Hs 578T | TNBC | Basal B | Gemcitabine | DNA replication | DNA replication | 0.00185 | uM | 7863.011 | 0.9312 | 0.9307 | 2.0237 | |
| Hs 578T | TNBC | Basal B | Gemcitabine | DNA replication | DNA replication | 0.00925 | uM | 7863.011 | 0.9672 | 0.9673 | 2.0237 | |
| Hs 578T | TNBC | Basal B | Gemcitabine | DNA replication | DNA replication | 0.0462 | uM | 7863.011 | 1.0037 | 1.0037 | 2.0237 | |
| Hs 578T | TNBC | Basal B | Gemcitabine | DNA replication | DNA replication | 0.231 | uM | 7863.011 | 1.0004 | 1.0004 | 2.0237 | |
| Hs 578T | TNBC | Basal B | Gemcitabine | DNA replication | DNA replication | 1.16 | uM | 7863.011 | 0.8733 | 0.8705 | 2.0237 | |
| Hs 578T | TNBC | Basal B | Gemcitabine | DNA replication | DNA replication | 5.78 | uM | 7863.011 | 0.5353 | 0.4686 | 2.0237 | |
| Hs 578T | TNBC | Basal B | Gemcitabine | DNA replication | DNA replication | 28.9 | uM | 7863.011 | 0.3241 | 0.1461 | 2.0237 | |
| Hs 578T | TNBC | Basal B | Gemcitabine | DNA replication | DNA replication | 144 | uM | 7863.011 | 0.2816 | 0.0692 | 2.0237 | |
| Hs 578T | TNBC | Basal B | Gemcitabine | DNA replication | DNA replication | 0.00037 | uM | 7864.011 | 0.9194 | 0.8898 | 1.4831 | |
| Hs 578T | TNBC | Basal B | Gemcitabine | DNA replication | DNA replication | 0.00185 | uM | 7864.011 | 1.0781 | 1.1040 | 1.4831 | |
| Hs 578T | TNBC | Basal B | Gemcitabine | DNA replication | DNA replication | 0.00925 | uM | 7864.011 | 1.0306 | 1.0410 | 1.4831 |