Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC70 | TNBC | Basal A | Gemcitabine | DNA replication | DNA replication | 28.9 | uM | 7860.011 | 0.9387 | 0.8304 | 0.7135 | |
| HCC70 | TNBC | Basal A | Gemcitabine | DNA replication | DNA replication | 144 | uM | 7860.011 | 0.9279 | 0.8007 | 0.7135 | |
| HCC70 | TNBC | Basal A | Gemcitabine | DNA replication | DNA replication | 0.00037 | uM | 9501.011 | 0.9808 | 0.9587 | 0.9301 | |
| HCC70 | TNBC | Basal A | Gemcitabine | DNA replication | DNA replication | 0.00185 | uM | 9501.011 | 0.9508 | 0.8943 | 0.9301 | |
| HCC70 | TNBC | Basal A | Gemcitabine | DNA replication | DNA replication | 0.00925 | uM | 9501.011 | 0.9558 | 0.9052 | 0.9301 | |
| HCC70 | TNBC | Basal A | Gemcitabine | DNA replication | DNA replication | 0.0462 | uM | 9501.011 | 0.9096 | 0.8062 | 0.9301 | |
| HCC70 | TNBC | Basal A | Gemcitabine | DNA replication | DNA replication | 0.231 | uM | 9501.011 | 0.9523 | 0.8977 | 0.9301 | |
| HCC70 | TNBC | Basal A | Gemcitabine | DNA replication | DNA replication | 1.16 | uM | 9501.011 | 0.8525 | 0.6846 | 0.9301 | |
| HCC70 | TNBC | Basal A | Gemcitabine | DNA replication | DNA replication | 5.78 | uM | 9501.011 | 0.7019 | 0.3670 | 0.9301 | |
| HCC70 | TNBC | Basal A | Gemcitabine | DNA replication | DNA replication | 28.9 | uM | 9501.011 | 0.6876 | 0.3371 | 0.9301 | |
| HCC70 | TNBC | Basal A | Gemcitabine | DNA replication | DNA replication | 144 | uM | 9501.011 | 0.7262 | 0.4180 | 0.9301 | |
| HCC70 | TNBC | Basal A | Gemcitabine | DNA replication | DNA replication | 0.000325 | uM | 9501.03 | 0.9219 | 0.7776 | 0.6902 | |
| HCC70 | TNBC | Basal A | Gemcitabine | DNA replication | DNA replication | 0.00162 | uM | 9501.03 | 1.0205 | 1.0595 | 0.6902 | |
| HCC70 | TNBC | Basal A | Gemcitabine | DNA replication | DNA replication | 0.00812 | uM | 9501.03 | 0.9940 | 0.9826 | 0.6902 | |
| HCC70 | TNBC | Basal A | Gemcitabine | DNA replication | DNA replication | 0.0406 | uM | 9501.03 | 0.9230 | 0.7807 | 0.6902 | |
| HCC70 | TNBC | Basal A | Gemcitabine | DNA replication | DNA replication | 0.203 | uM | 9501.03 | 0.7529 | 0.3256 | 0.6902 | |
| HCC70 | TNBC | Basal A | Gemcitabine | DNA replication | DNA replication | 1.01 | uM | 9501.03 | 0.8533 | 0.5893 | 0.6902 | |
| HCC70 | TNBC | Basal A | Gemcitabine | DNA replication | DNA replication | 5.07 | uM | 9501.03 | 0.8580 | 0.6019 | 0.6902 | |
| HCC70 | TNBC | Basal A | Gemcitabine | DNA replication | DNA replication | 25.4 | uM | 9501.03 | 0.6601 | 0.0955 | 0.6902 | |
| HCC70 | TNBC | Basal A | Gemcitabine | DNA replication | DNA replication | 127 | uM | 9501.03 | 0.3240 | -0.6094 | 0.6902 | |
| HMT-3522 S1 | Unknown | Unknown | Gemcitabine | DNA replication | DNA replication | 0.00037 | uM | 7911.011 | 0.9843 | 0.9805 | 1.6150 | |
| HMT-3522 S1 | Unknown | Unknown | Gemcitabine | DNA replication | DNA replication | 0.00185 | uM | 7911.011 | 1.0345 | 1.0425 | 1.6150 | |
| HMT-3522 S1 | Unknown | Unknown | Gemcitabine | DNA replication | DNA replication | 0.00925 | uM | 7911.011 | 0.9809 | 0.9763 | 1.6150 | |
| HMT-3522 S1 | Unknown | Unknown | Gemcitabine | DNA replication | DNA replication | 0.0462 | uM | 7911.011 | 0.5746 | 0.4191 | 1.6150 | |
| HMT-3522 S1 | Unknown | Unknown | Gemcitabine | DNA replication | DNA replication | 0.231 | uM | 7911.011 | 0.5996 | 0.4571 | 1.6150 |