Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC38 | TNBC | Basal B | Gemcitabine | DNA replication | DNA replication | 0.000168 | uM | 10268.12 | 1.1934 | 2.4334 | 0.3272 | |
| HCC38 | TNBC | Basal B | Gemcitabine | DNA replication | DNA replication | 0.00084 | uM | 10268.12 | 1.3328 | 3.8126 | 0.3272 | |
| HCC38 | TNBC | Basal B | Gemcitabine | DNA replication | DNA replication | 0.0042 | uM | 10268.12 | 0.1788 | -0.9896 | 0.3272 | |
| HCC38 | TNBC | Basal B | Gemcitabine | DNA replication | DNA replication | 0.021 | uM | 10268.12 | 0.1455 | -0.9945 | 0.3272 | |
| HCC38 | TNBC | Basal B | Gemcitabine | DNA replication | DNA replication | 0.105 | uM | 10268.12 | 0.0686 | -0.9995 | 0.3272 | |
| HCC38 | TNBC | Basal B | Gemcitabine | DNA replication | DNA replication | 0.525 | uM | 10268.12 | 0.0986 | -0.9983 | 0.3272 | |
| HCC38 | TNBC | Basal B | Gemcitabine | DNA replication | DNA replication | 2.62 | uM | 10268.12 | 0.0669 | -0.9995 | 0.3272 | |
| HCC38 | TNBC | Basal B | Gemcitabine | DNA replication | DNA replication | 13.1 | uM | 10268.12 | 0.0689 | -0.9994 | 0.3272 | |
| HCC38 | TNBC | Basal B | Gemcitabine | DNA replication | DNA replication | 65.6 | uM | 10268.12 | 0.0733 | -0.9993 | 0.3272 | |
| HCC70 | TNBC | Basal A | Gemcitabine | DNA replication | DNA replication | 0.00037 | uM | 7857.011 | 1.0610 | 1.1162 | 1.0477 | |
| HCC70 | TNBC | Basal A | Gemcitabine | DNA replication | DNA replication | 0.00185 | uM | 7857.011 | 0.9902 | 0.9813 | 1.0477 | |
| HCC70 | TNBC | Basal A | Gemcitabine | DNA replication | DNA replication | 0.00925 | uM | 7857.011 | 0.8242 | 0.6630 | 1.0477 | |
| HCC70 | TNBC | Basal A | Gemcitabine | DNA replication | DNA replication | 0.0462 | uM | 7857.011 | 0.8353 | 0.6842 | 1.0477 | |
| HCC70 | TNBC | Basal A | Gemcitabine | DNA replication | DNA replication | 0.231 | uM | 7857.011 | 0.7976 | 0.6116 | 1.0477 | |
| HCC70 | TNBC | Basal A | Gemcitabine | DNA replication | DNA replication | 1.16 | uM | 7857.011 | 0.7657 | 0.5502 | 1.0477 | |
| HCC70 | TNBC | Basal A | Gemcitabine | DNA replication | DNA replication | 5.78 | uM | 7857.011 | 0.7016 | 0.4261 | 1.0477 | |
| HCC70 | TNBC | Basal A | Gemcitabine | DNA replication | DNA replication | 28.9 | uM | 7857.011 | 0.6800 | 0.3841 | 1.0477 | |
| HCC70 | TNBC | Basal A | Gemcitabine | DNA replication | DNA replication | 144 | uM | 7857.011 | 0.8345 | 0.6827 | 1.0477 | |
| HCC70 | TNBC | Basal A | Gemcitabine | DNA replication | DNA replication | 0.00037 | uM | 7860.011 | 1.0196 | 1.0550 | 0.7135 | |
| HCC70 | TNBC | Basal A | Gemcitabine | DNA replication | DNA replication | 0.00185 | uM | 7860.011 | 0.9860 | 0.9610 | 0.7135 | |
| HCC70 | TNBC | Basal A | Gemcitabine | DNA replication | DNA replication | 0.00925 | uM | 7860.011 | 0.9938 | 0.9825 | 0.7135 | |
| HCC70 | TNBC | Basal A | Gemcitabine | DNA replication | DNA replication | 0.0462 | uM | 7860.011 | 0.9628 | 0.8964 | 0.7135 | |
| HCC70 | TNBC | Basal A | Gemcitabine | DNA replication | DNA replication | 0.231 | uM | 7860.011 | 1.0103 | 1.0289 | 0.7135 | |
| HCC70 | TNBC | Basal A | Gemcitabine | DNA replication | DNA replication | 1.16 | uM | 7860.011 | 0.9897 | 0.9712 | 0.7135 | |
| HCC70 | TNBC | Basal A | Gemcitabine | DNA replication | DNA replication | 5.78 | uM | 7860.011 | 0.9582 | 0.8837 | 0.7135 |