Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC38 | TNBC | Basal B | Gemcitabine | DNA replication | DNA replication | 0.00925 | uM | 9453.011 | 1.0475 | 1.1230 | 0.7773 | |
| HCC38 | TNBC | Basal B | Gemcitabine | DNA replication | DNA replication | 0.0462 | uM | 9453.011 | 0.1407 | -0.8396 | 0.7773 | |
| HCC38 | TNBC | Basal B | Gemcitabine | DNA replication | DNA replication | 0.231 | uM | 9453.011 | 0.1087 | -0.8849 | 0.7773 | |
| HCC38 | TNBC | Basal B | Gemcitabine | DNA replication | DNA replication | 1.16 | uM | 9453.011 | 0.1083 | -0.8854 | 0.7773 | |
| HCC38 | TNBC | Basal B | Gemcitabine | DNA replication | DNA replication | 5.78 | uM | 9453.011 | 0.0917 | -0.9075 | 0.7773 | |
| HCC38 | TNBC | Basal B | Gemcitabine | DNA replication | DNA replication | 28.9 | uM | 9453.011 | 0.0944 | -0.9040 | 0.7773 | |
| HCC38 | TNBC | Basal B | Gemcitabine | DNA replication | DNA replication | 144 | uM | 9453.011 | 0.0921 | -0.9070 | 0.7773 | |
| HCC38 | TNBC | Basal B | Gemcitabine | DNA replication | DNA replication | 0.00037 | uM | 9469.011 | 0.9533 | 0.9218 | 1.1991 | |
| HCC38 | TNBC | Basal B | Gemcitabine | DNA replication | DNA replication | 0.00185 | uM | 9469.011 | 0.9792 | 0.9653 | 1.1991 | |
| HCC38 | TNBC | Basal B | Gemcitabine | DNA replication | DNA replication | 0.00925 | uM | 9469.011 | 0.2233 | -0.4273 | 1.1991 | |
| HCC38 | TNBC | Basal B | Gemcitabine | DNA replication | DNA replication | 0.0462 | uM | 9469.011 | 0.1399 | -0.6123 | 1.1991 | |
| HCC38 | TNBC | Basal B | Gemcitabine | DNA replication | DNA replication | 0.231 | uM | 9469.011 | 0.1068 | -0.6903 | 1.1991 | |
| HCC38 | TNBC | Basal B | Gemcitabine | DNA replication | DNA replication | 1.16 | uM | 9469.011 | 0.1095 | -0.6840 | 1.1991 | |
| HCC38 | TNBC | Basal B | Gemcitabine | DNA replication | DNA replication | 5.78 | uM | 9469.011 | 0.0897 | -0.7323 | 1.1991 | |
| HCC38 | TNBC | Basal B | Gemcitabine | DNA replication | DNA replication | 28.9 | uM | 9469.011 | 0.0855 | -0.7427 | 1.1991 | |
| HCC38 | TNBC | Basal B | Gemcitabine | DNA replication | DNA replication | 144 | uM | 9469.011 | 0.0940 | -0.7217 | 1.1991 | |
| HCC38 | TNBC | Basal B | Gemcitabine | DNA replication | DNA replication | 0.0185 | uM | 9469.131 | 0.1669 | -0.6291 | 1.0627 | |
| HCC38 | TNBC | Basal B | Gemcitabine | DNA replication | DNA replication | 0.0924 | uM | 9469.131 | 0.1308 | -0.7051 | 1.0627 | |
| HCC38 | TNBC | Basal B | Gemcitabine | DNA replication | DNA replication | 0.462 | uM | 9469.131 | 0.1017 | -0.7672 | 1.0627 | |
| HCC38 | TNBC | Basal B | Gemcitabine | DNA replication | DNA replication | 2.31 | uM | 9469.131 | 0.6892 | 0.4089 | 1.0627 | |
| HCC38 | TNBC | Basal B | Gemcitabine | DNA replication | DNA replication | 11.6 | uM | 9469.131 | 0.0916 | -0.7892 | 1.0627 | |
| HCC38 | TNBC | Basal B | Gemcitabine | DNA replication | DNA replication | 57.8 | uM | 9469.131 | 0.4057 | -0.1442 | 1.0627 | |
| HCC38 | TNBC | Basal B | Gemcitabine | DNA replication | DNA replication | 289 | uM | 9469.131 | 0.0981 | -0.7750 | 1.0627 | |
| HCC38 | TNBC | Basal B | Gemcitabine | DNA replication | DNA replication | 1440 | uM | 9469.131 | 0.0875 | -0.7980 | 1.0627 | |
| HCC38 | TNBC | Basal B | Gemcitabine | DNA replication | DNA replication | 7220 | uM | 9469.131 | 0.3423 | -0.2707 | 1.0627 |