Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
Download: Excel (XLSX), Comma-separated (CSV)
| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC1187 | TNBC | Basal A | Gemcitabine | DNA replication | DNA replication | 0.00925 | uM | 7811.011 | 0.9900 | 0.9547 | 0.4400 | |
| HCC1187 | TNBC | Basal A | Gemcitabine | DNA replication | DNA replication | 0.0462 | uM | 7811.011 | 1.0575 | 1.2709 | 0.4400 | |
| HCC1187 | TNBC | Basal A | Gemcitabine | DNA replication | DNA replication | 0.231 | uM | 7811.011 | 0.8846 | 0.5134 | 0.4400 | |
| HCC1187 | TNBC | Basal A | Gemcitabine | DNA replication | DNA replication | 1.16 | uM | 7811.011 | 0.7778 | 0.1298 | 0.4400 | |
| HCC1187 | TNBC | Basal A | Gemcitabine | DNA replication | DNA replication | 5.78 | uM | 7811.011 | 0.5816 | -0.4164 | 0.4400 | |
| HCC1187 | TNBC | Basal A | Gemcitabine | DNA replication | DNA replication | 28.9 | uM | 7811.011 | 0.6324 | -0.2941 | 0.4400 | |
| HCC1187 | TNBC | Basal A | Gemcitabine | DNA replication | DNA replication | 144 | uM | 7811.011 | 0.6797 | -0.1683 | 0.4400 | |
| HCC1187 | TNBC | Basal A | Gemcitabine | DNA replication | DNA replication | 0.00037 | uM | 7812.011 | 1.0869 | 1.1632 | 1.0620 | |
| HCC1187 | TNBC | Basal A | Gemcitabine | DNA replication | DNA replication | 0.00185 | uM | 7812.011 | 0.8881 | 0.7886 | 1.0620 | |
| HCC1187 | TNBC | Basal A | Gemcitabine | DNA replication | DNA replication | 0.00925 | uM | 7812.011 | 1.0328 | 1.0616 | 1.0620 | |
| HCC1187 | TNBC | Basal A | Gemcitabine | DNA replication | DNA replication | 0.0462 | uM | 7812.011 | 0.9008 | 0.8127 | 1.0620 | |
| HCC1187 | TNBC | Basal A | Gemcitabine | DNA replication | DNA replication | 0.231 | uM | 7812.011 | 0.8482 | 0.7127 | 1.0620 | |
| HCC1187 | TNBC | Basal A | Gemcitabine | DNA replication | DNA replication | 1.16 | uM | 7812.011 | 0.8540 | 0.7238 | 1.0620 | |
| HCC1187 | TNBC | Basal A | Gemcitabine | DNA replication | DNA replication | 5.78 | uM | 7812.011 | 0.7811 | 0.5849 | 1.0620 | |
| HCC1187 | TNBC | Basal A | Gemcitabine | DNA replication | DNA replication | 28.9 | uM | 7812.011 | 0.8134 | 0.6465 | 1.0620 | |
| HCC1187 | TNBC | Basal A | Gemcitabine | DNA replication | DNA replication | 144 | uM | 7812.011 | 0.7200 | 0.4679 | 1.0620 | |
| HCC1395 | TNBC | Basal B | Gemcitabine | DNA replication | DNA replication | 0.00037 | uM | 7813.011 | 1.1012 | 1.2337 | 0.8718 | |
| HCC1395 | TNBC | Basal B | Gemcitabine | DNA replication | DNA replication | 0.00185 | uM | 7813.011 | 0.8784 | 0.7235 | 0.8718 | |
| HCC1395 | TNBC | Basal B | Gemcitabine | DNA replication | DNA replication | 0.00925 | uM | 7813.011 | 1.2149 | 1.5003 | 0.8718 | |
| HCC1395 | TNBC | Basal B | Gemcitabine | DNA replication | DNA replication | 0.0462 | uM | 7813.011 | 1.0873 | 1.2015 | 0.8718 | |
| HCC1395 | TNBC | Basal B | Gemcitabine | DNA replication | DNA replication | 0.231 | uM | 7813.011 | 1.0740 | 1.1708 | 0.8718 | |
| HCC1395 | TNBC | Basal B | Gemcitabine | DNA replication | DNA replication | 1.16 | uM | 7813.011 | 1.0648 | 1.1493 | 0.8718 | |
| HCC1395 | TNBC | Basal B | Gemcitabine | DNA replication | DNA replication | 5.78 | uM | 7813.011 | 0.7494 | 0.4366 | 0.8718 | |
| HCC1395 | TNBC | Basal B | Gemcitabine | DNA replication | DNA replication | 28.9 | uM | 7813.011 | 0.8301 | 0.6153 | 0.8718 | |
| HCC1395 | TNBC | Basal B | Gemcitabine | DNA replication | DNA replication | 144 | uM | 7813.011 | 0.8638 | 0.6908 | 0.8718 |