Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Hs 578T | TNBC | Basal B | Gemcitabine | DNA replication | DNA replication | 0.0462 | uM | 7864.011 | 0.9776 | 0.9697 | 1.4831 | |
| Hs 578T | TNBC | Basal B | Gemcitabine | DNA replication | DNA replication | 0.231 | uM | 7864.011 | 0.8844 | 0.8410 | 1.4831 | |
| Hs 578T | TNBC | Basal B | Gemcitabine | DNA replication | DNA replication | 1.16 | uM | 7864.011 | 0.8709 | 0.8220 | 1.4831 | |
| Hs 578T | TNBC | Basal B | Gemcitabine | DNA replication | DNA replication | 5.78 | uM | 7864.011 | 0.4248 | 0.1228 | 1.4831 | |
| Hs 578T | TNBC | Basal B | Gemcitabine | DNA replication | DNA replication | 28.9 | uM | 7864.011 | 0.4534 | 0.1733 | 1.4831 | |
| Hs 578T | TNBC | Basal B | Gemcitabine | DNA replication | DNA replication | 144 | uM | 7864.011 | 0.6010 | 0.4188 | 1.4831 | |
| LY2 | HR+ | Luminal | Gemcitabine | DNA replication | DNA replication | 0.00037 | uM | 9536.011 | 1.0549 | 1.0863 | 1.2640 | |
| LY2 | HR+ | Luminal | Gemcitabine | DNA replication | DNA replication | 0.00185 | uM | 9536.011 | 0.9230 | 0.8771 | 1.2640 | |
| LY2 | HR+ | Luminal | Gemcitabine | DNA replication | DNA replication | 0.00925 | uM | 9536.011 | 0.9633 | 0.9417 | 1.2640 | |
| LY2 | HR+ | Luminal | Gemcitabine | DNA replication | DNA replication | 0.0462 | uM | 9536.011 | 0.6833 | 0.4797 | 1.2640 | |
| LY2 | HR+ | Luminal | Gemcitabine | DNA replication | DNA replication | 0.231 | uM | 9536.011 | 0.6831 | 0.4794 | 1.2640 | |
| LY2 | HR+ | Luminal | Gemcitabine | DNA replication | DNA replication | 1.16 | uM | 9536.011 | 0.6754 | 0.4662 | 1.2640 | |
| LY2 | HR+ | Luminal | Gemcitabine | DNA replication | DNA replication | 5.78 | uM | 9536.011 | 0.6578 | 0.4359 | 1.2640 | |
| LY2 | HR+ | Luminal | Gemcitabine | DNA replication | DNA replication | 28.9 | uM | 9536.011 | 0.6976 | 0.5042 | 1.2640 | |
| LY2 | HR+ | Luminal | Gemcitabine | DNA replication | DNA replication | 144 | uM | 9536.011 | 0.6522 | 0.4261 | 1.2640 | |
| LY2 | HR+ | Luminal | Gemcitabine | DNA replication | DNA replication | 0.00037 | uM | 10264.011 | 1.0128 | 1.0183 | 1.3983 | |
| LY2 | HR+ | Luminal | Gemcitabine | DNA replication | DNA replication | 0.00185 | uM | 10264.011 | 1.0193 | 1.0275 | 1.3983 | |
| LY2 | HR+ | Luminal | Gemcitabine | DNA replication | DNA replication | 0.00925 | uM | 10264.011 | 0.8375 | 0.7617 | 1.3983 | |
| LY2 | HR+ | Luminal | Gemcitabine | DNA replication | DNA replication | 0.0462 | uM | 10264.011 | 0.6192 | 0.4195 | 1.3983 | |
| LY2 | HR+ | Luminal | Gemcitabine | DNA replication | DNA replication | 0.231 | uM | 10264.011 | 0.6403 | 0.4540 | 1.3983 | |
| LY2 | HR+ | Luminal | Gemcitabine | DNA replication | DNA replication | 1.16 | uM | 10264.011 | 0.6202 | 0.4213 | 1.3983 | |
| LY2 | HR+ | Luminal | Gemcitabine | DNA replication | DNA replication | 5.78 | uM | 10264.011 | 0.6823 | 0.5216 | 1.3983 | |
| LY2 | HR+ | Luminal | Gemcitabine | DNA replication | DNA replication | 28.9 | uM | 10264.011 | 0.6325 | 0.4413 | 1.3983 | |
| LY2 | HR+ | Luminal | Gemcitabine | DNA replication | DNA replication | 144 | uM | 10264.011 | 0.6090 | 0.4029 | 1.3983 | |
| LY2 | HR+ | Luminal | Gemcitabine | DNA replication | DNA replication | 0.0185 | uM | 10264.131 | 0.7268 | 0.6061 | 1.4548 |