Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AU565 | HER2amp | Luminal | Glycyl-H-1152 | ROCK2 | 1.33 | uM | 10880.15 | 0.7985 | 0.7350 | 1.5829 | ||
| AU565 | HER2amp | Luminal | Glycyl-H-1152 | ROCK2 | 6.67 | uM | 10880.15 | 0.6909 | 0.5834 | 1.5829 | ||
| AU565 | HER2amp | Luminal | Glycyl-H-1152 | ROCK2 | 33.3 | uM | 10880.15 | 0.4460 | 0.2009 | 1.5829 | ||
| BT-20 | TNBC | Basal A | Glycyl-H-1152 | ROCK2 | 0.0000853 | uM | 10581.138 | 0.9886 | 0.9759 | 0.9462 | ||
| BT-20 | TNBC | Basal A | Glycyl-H-1152 | ROCK2 | 0.000427 | uM | 10581.138 | 0.9072 | 0.8044 | 0.9462 | ||
| BT-20 | TNBC | Basal A | Glycyl-H-1152 | ROCK2 | 0.00213 | uM | 10581.138 | 0.9575 | 0.9102 | 0.9462 | ||
| BT-20 | TNBC | Basal A | Glycyl-H-1152 | ROCK2 | 0.0107 | uM | 10581.138 | 0.9484 | 0.8911 | 0.9462 | ||
| BT-20 | TNBC | Basal A | Glycyl-H-1152 | ROCK2 | 0.0533 | uM | 10581.138 | 0.9920 | 0.9831 | 0.9462 | ||
| BT-20 | TNBC | Basal A | Glycyl-H-1152 | ROCK2 | 0.267 | uM | 10581.138 | 0.9693 | 0.9352 | 0.9462 | ||
| BT-20 | TNBC | Basal A | Glycyl-H-1152 | ROCK2 | 1.33 | uM | 10581.138 | 0.8344 | 0.6516 | 0.9462 | ||
| BT-20 | TNBC | Basal A | Glycyl-H-1152 | ROCK2 | 6.67 | uM | 10581.138 | 0.7392 | 0.4533 | 0.9462 | ||
| BT-20 | TNBC | Basal A | Glycyl-H-1152 | ROCK2 | 33.3 | uM | 10581.138 | 0.6744 | 0.3189 | 0.9462 | ||
| BT-20 | TNBC | Basal A | Glycyl-H-1152 | ROCK2 | 0.000171 | uM | 11854.16 | 0.9944 | 0.9915 | 1.3102 | ||
| BT-20 | TNBC | Basal A | Glycyl-H-1152 | ROCK2 | 0.000853 | uM | 11854.16 | 0.9758 | 0.9630 | 1.3102 | ||
| BT-20 | TNBC | Basal A | Glycyl-H-1152 | ROCK2 | 0.00427 | uM | 11854.16 | 0.9579 | 0.9354 | 1.3102 | ||
| BT-20 | TNBC | Basal A | Glycyl-H-1152 | ROCK2 | 0.0213 | uM | 11854.16 | 1.0454 | 1.0690 | 1.3102 | ||
| BT-20 | TNBC | Basal A | Glycyl-H-1152 | ROCK2 | 0.107 | uM | 11854.16 | 0.9566 | 0.9334 | 1.3102 | ||
| BT-20 | TNBC | Basal A | Glycyl-H-1152 | ROCK2 | 0.533 | uM | 11854.16 | 0.9320 | 0.8953 | 1.3102 | ||
| BT-20 | TNBC | Basal A | Glycyl-H-1152 | ROCK2 | 2.67 | uM | 11854.16 | 0.8154 | 0.7115 | 1.3102 | ||
| BT-20 | TNBC | Basal A | Glycyl-H-1152 | ROCK2 | 13.3 | uM | 11854.16 | 0.6873 | 0.5022 | 1.3102 | ||
| BT-20 | TNBC | Basal A | Glycyl-H-1152 | ROCK2 | 66.7 | uM | 11854.16 | 0.6486 | 0.4372 | 1.3102 | ||
| BT-474 | HER2amp | Luminal | Glycyl-H-1152 | ROCK2 | 0.000171 | uM | 12056.16 | 0.9812 | 0.9588 | 0.9124 | ||
| BT-474 | HER2amp | Luminal | Glycyl-H-1152 | ROCK2 | 0.000853 | uM | 12056.16 | 0.9852 | 0.9676 | 0.9124 | ||
| BT-474 | HER2amp | Luminal | Glycyl-H-1152 | ROCK2 | 0.00427 | uM | 12056.16 | 0.9396 | 0.8681 | 0.9124 | ||
| BT-474 | HER2amp | Luminal | Glycyl-H-1152 | ROCK2 | 0.0213 | uM | 12056.16 | 1.0018 | 1.0039 | 0.9124 |