Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| BT-474 | HER2amp | Luminal | Glycyl-H-1152 | ROCK2 | 0.107 | uM | 12056.16 | 0.9223 | 0.8304 | 0.9124 | ||
| BT-474 | HER2amp | Luminal | Glycyl-H-1152 | ROCK2 | 0.533 | uM | 12056.16 | 0.9981 | 0.9958 | 0.9124 | ||
| BT-474 | HER2amp | Luminal | Glycyl-H-1152 | ROCK2 | 2.67 | uM | 12056.16 | 0.9791 | 0.9542 | 0.9124 | ||
| BT-474 | HER2amp | Luminal | Glycyl-H-1152 | ROCK2 | 13.3 | uM | 12056.16 | 0.8449 | 0.6628 | 0.9124 | ||
| BT-474 | HER2amp | Luminal | Glycyl-H-1152 | ROCK2 | 66.7 | uM | 12056.16 | 0.8890 | 0.7581 | 0.9124 | ||
| BT-474 | HER2amp | Luminal | Glycyl-H-1152 | ROCK2 | 0.000171 | uM | 12178.16 | 0.9251 | 0.8002 | 0.7392 | ||
| BT-474 | HER2amp | Luminal | Glycyl-H-1152 | ROCK2 | 0.000853 | uM | 12178.16 | 0.9749 | 0.9323 | 0.7392 | ||
| BT-474 | HER2amp | Luminal | Glycyl-H-1152 | ROCK2 | 0.00427 | uM | 12178.16 | 0.9316 | 0.8172 | 0.7392 | ||
| BT-474 | HER2amp | Luminal | Glycyl-H-1152 | ROCK2 | 0.0213 | uM | 12178.16 | 0.9839 | 0.9565 | 0.7392 | ||
| BT-474 | HER2amp | Luminal | Glycyl-H-1152 | ROCK2 | 0.107 | uM | 12178.16 | 0.8613 | 0.6342 | 0.7392 | ||
| BT-474 | HER2amp | Luminal | Glycyl-H-1152 | ROCK2 | 0.533 | uM | 12178.16 | 0.9725 | 0.9259 | 0.7392 | ||
| BT-474 | HER2amp | Luminal | Glycyl-H-1152 | ROCK2 | 2.67 | uM | 12178.16 | 0.9639 | 0.9029 | 0.7392 | ||
| BT-474 | HER2amp | Luminal | Glycyl-H-1152 | ROCK2 | 13.3 | uM | 12178.16 | 0.9063 | 0.7508 | 0.7392 | ||
| BT-474 | HER2amp | Luminal | Glycyl-H-1152 | ROCK2 | 66.7 | uM | 12178.16 | 0.9198 | 0.7861 | 0.7392 | ||
| BT-474 | HER2amp | Luminal | Glycyl-H-1152 | ROCK2 | 0.000171 | uM | 12291.169 | 1.0303 | 1.1753 | 0.3548 | ||
| BT-474 | HER2amp | Luminal | Glycyl-H-1152 | ROCK2 | 0.000853 | uM | 12291.169 | 1.0571 | 1.3388 | 0.3548 | ||
| BT-474 | HER2amp | Luminal | Glycyl-H-1152 | ROCK2 | 0.00427 | uM | 12291.169 | 1.0957 | 1.5874 | 0.3548 | ||
| BT-474 | HER2amp | Luminal | Glycyl-H-1152 | ROCK2 | 0.0213 | uM | 12291.169 | 1.0079 | 1.0447 | 0.3548 | ||
| BT-474 | HER2amp | Luminal | Glycyl-H-1152 | ROCK2 | 0.107 | uM | 12291.169 | 1.0057 | 1.0323 | 0.3548 | ||
| BT-474 | HER2amp | Luminal | Glycyl-H-1152 | ROCK2 | 0.533 | uM | 12291.169 | 1.0857 | 1.5215 | 0.3548 | ||
| BT-474 | HER2amp | Luminal | Glycyl-H-1152 | ROCK2 | 2.67 | uM | 12291.169 | 1.0349 | 1.2030 | 0.3548 | ||
| BT-474 | HER2amp | Luminal | Glycyl-H-1152 | ROCK2 | 13.3 | uM | 12291.169 | 1.0439 | 1.2576 | 0.3548 | ||
| BT-474 | HER2amp | Luminal | Glycyl-H-1152 | ROCK2 | 66.7 | uM | 12291.169 | 0.9811 | 0.8955 | 0.3548 | ||
| BT-483 | HR+ | Luminal | Glycyl-H-1152 | ROCK2 | 0.0000853 | uM | 10696.15 | 1.0322 | 1.1383 | 0.4740 | ||
| BT-483 | HR+ | Luminal | Glycyl-H-1152 | ROCK2 | 0.000427 | uM | 10696.15 | 0.9527 | 0.8055 | 0.4740 |