Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
Download: Excel (XLSX), Comma-separated (CSV)
| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| BT-483 | HR+ | Luminal | Glycyl-H-1152 | ROCK2 | 0.00213 | uM | 10696.15 | 0.9713 | 0.8809 | 0.4740 | ||
| BT-483 | HR+ | Luminal | Glycyl-H-1152 | ROCK2 | 0.0107 | uM | 10696.15 | 0.9780 | 0.9083 | 0.4740 | ||
| BT-483 | HR+ | Luminal | Glycyl-H-1152 | ROCK2 | 0.0533 | uM | 10696.15 | 1.0076 | 1.0321 | 0.4740 | ||
| BT-483 | HR+ | Luminal | Glycyl-H-1152 | ROCK2 | 0.267 | uM | 10696.15 | 1.0519 | 1.2253 | 0.4740 | ||
| BT-483 | HR+ | Luminal | Glycyl-H-1152 | ROCK2 | 1.33 | uM | 10696.15 | 1.0144 | 1.0614 | 0.4740 | ||
| BT-483 | HR+ | Luminal | Glycyl-H-1152 | ROCK2 | 6.67 | uM | 10696.15 | 0.9661 | 0.8597 | 0.4740 | ||
| BT-483 | HR+ | Luminal | Glycyl-H-1152 | ROCK2 | 33.3 | uM | 10696.15 | 0.8369 | 0.3736 | 0.4740 | ||
| BT-483 | HR+ | Luminal | Glycyl-H-1152 | ROCK2 | 0.000171 | uM | 11855.16 | 0.9418 | 0.8232 | 0.6477 | ||
| BT-483 | HR+ | Luminal | Glycyl-H-1152 | ROCK2 | 0.000853 | uM | 11855.16 | 0.8678 | 0.6069 | 0.6477 | ||
| BT-483 | HR+ | Luminal | Glycyl-H-1152 | ROCK2 | 0.00427 | uM | 11855.16 | 0.8991 | 0.6971 | 0.6477 | ||
| BT-483 | HR+ | Luminal | Glycyl-H-1152 | ROCK2 | 0.0213 | uM | 11855.16 | 0.8923 | 0.6773 | 0.6477 | ||
| BT-483 | HR+ | Luminal | Glycyl-H-1152 | ROCK2 | 0.107 | uM | 11855.16 | 0.9194 | 0.7566 | 0.6477 | ||
| BT-483 | HR+ | Luminal | Glycyl-H-1152 | ROCK2 | 0.533 | uM | 11855.16 | 0.9624 | 0.8850 | 0.6477 | ||
| BT-483 | HR+ | Luminal | Glycyl-H-1152 | ROCK2 | 2.67 | uM | 11855.16 | 0.8859 | 0.6588 | 0.6477 | ||
| BT-483 | HR+ | Luminal | Glycyl-H-1152 | ROCK2 | 13.3 | uM | 11855.16 | 0.8954 | 0.6864 | 0.6477 | ||
| BT-483 | HR+ | Luminal | Glycyl-H-1152 | ROCK2 | 66.7 | uM | 11855.16 | 0.8029 | 0.4252 | 0.6477 | ||
| BT-549 | TNBC | Basal B | Glycyl-H-1152 | ROCK2 | 0.000171 | uM | 12305.169 | 1.1001 | 1.0754 | 2.5786 | ||
| BT-549 | TNBC | Basal B | Glycyl-H-1152 | ROCK2 | 0.000853 | uM | 12305.169 | 1.1330 | 1.0992 | 2.5786 | ||
| BT-549 | TNBC | Basal B | Glycyl-H-1152 | ROCK2 | 0.00427 | uM | 12305.169 | 1.0474 | 1.0362 | 2.5786 | ||
| BT-549 | TNBC | Basal B | Glycyl-H-1152 | ROCK2 | 0.0213 | uM | 12305.169 | 1.0674 | 1.0512 | 2.5786 | ||
| BT-549 | TNBC | Basal B | Glycyl-H-1152 | ROCK2 | 0.107 | uM | 12305.169 | 1.0916 | 1.0692 | 2.5786 | ||
| BT-549 | TNBC | Basal B | Glycyl-H-1152 | ROCK2 | 0.533 | uM | 12305.169 | 1.1035 | 1.0778 | 2.5786 | ||
| BT-549 | TNBC | Basal B | Glycyl-H-1152 | ROCK2 | 2.67 | uM | 12305.169 | 0.8951 | 0.9159 | 2.5786 | ||
| BT-549 | TNBC | Basal B | Glycyl-H-1152 | ROCK2 | 13.3 | uM | 12305.169 | 0.4809 | 0.5057 | 2.5786 | ||
| BT-549 | TNBC | Basal B | Glycyl-H-1152 | ROCK2 | 66.7 | uM | 12305.169 | 0.1733 | 0.0136 | 2.5786 |