Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SUM1315MO2 | TNBC | Basal B | Gemcitabine | DNA replication | DNA replication | 0.231 | uM | 9797.011 | 0.8563 | 0.4668 | 0.5004 | |
| SUM1315MO2 | TNBC | Basal B | Gemcitabine | DNA replication | DNA replication | 1.16 | uM | 9797.011 | 0.7464 | 0.1147 | 0.5004 | |
| SUM1315MO2 | TNBC | Basal B | Gemcitabine | DNA replication | DNA replication | 5.78 | uM | 9797.011 | 0.7619 | 0.1613 | 0.5004 | |
| SUM1315MO2 | TNBC | Basal B | Gemcitabine | DNA replication | DNA replication | 28.9 | uM | 9797.011 | 0.6342 | -0.1952 | 0.5004 | |
| SUM1315MO2 | TNBC | Basal B | Gemcitabine | DNA replication | DNA replication | 144 | uM | 9797.011 | 0.5271 | -0.4438 | 0.5004 | |
| SUM149PT | TNBC | Basal B | Gemcitabine | DNA replication | DNA replication | 0.00185 | uM | 7917.075 | 0.8891 | 0.9243 | 3.0479 | |
| SUM149PT | TNBC | Basal B | Gemcitabine | DNA replication | DNA replication | 0.00924 | uM | 7917.075 | 0.6450 | 0.7320 | 3.0479 | |
| SUM149PT | TNBC | Basal B | Gemcitabine | DNA replication | DNA replication | 0.0462 | uM | 7917.075 | 0.3309 | 0.3914 | 3.0479 | |
| SUM149PT | TNBC | Basal B | Gemcitabine | DNA replication | DNA replication | 0.231 | uM | 7917.075 | 0.3618 | 0.4327 | 3.0479 | |
| SUM149PT | TNBC | Basal B | Gemcitabine | DNA replication | DNA replication | 1.16 | uM | 7917.075 | 0.3259 | 0.3844 | 3.0479 | |
| SUM149PT | TNBC | Basal B | Gemcitabine | DNA replication | DNA replication | 5.78 | uM | 7917.075 | 0.2088 | 0.1963 | 3.0479 | |
| SUM149PT | TNBC | Basal B | Gemcitabine | DNA replication | DNA replication | 28.9 | uM | 7917.075 | 0.1554 | 0.0857 | 3.0479 | |
| SUM149PT | TNBC | Basal B | Gemcitabine | DNA replication | DNA replication | 144 | uM | 7917.075 | 0.1245 | 0.0096 | 3.0479 | |
| SUM149PT | TNBC | Basal B | Gemcitabine | DNA replication | DNA replication | 722 | uM | 7917.075 | 0.0958 | -0.0734 | 3.0479 | |
| SUM149PT | TNBC | Basal B | Gemcitabine | DNA replication | DNA replication | 0.00037 | uM | 9830.011 | 1.0577 | 1.0547 | 2.0792 | |
| SUM149PT | TNBC | Basal B | Gemcitabine | DNA replication | DNA replication | 0.00185 | uM | 9830.011 | 0.8918 | 0.8929 | 2.0792 | |
| SUM149PT | TNBC | Basal B | Gemcitabine | DNA replication | DNA replication | 0.00925 | uM | 9830.011 | 0.4795 | 0.4045 | 2.0792 | |
| SUM149PT | TNBC | Basal B | Gemcitabine | DNA replication | DNA replication | 0.0462 | uM | 9830.011 | 0.4536 | 0.3674 | 2.0792 | |
| SUM149PT | TNBC | Basal B | Gemcitabine | DNA replication | DNA replication | 0.231 | uM | 9830.011 | 0.4110 | 0.3041 | 2.0792 | |
| SUM149PT | TNBC | Basal B | Gemcitabine | DNA replication | DNA replication | 1.16 | uM | 9830.011 | 0.2006 | -0.0763 | 2.0792 | |
| SUM149PT | TNBC | Basal B | Gemcitabine | DNA replication | DNA replication | 5.78 | uM | 9830.011 | 0.1608 | -0.1697 | 2.0792 | |
| SUM149PT | TNBC | Basal B | Gemcitabine | DNA replication | DNA replication | 28.9 | uM | 9830.011 | 0.1562 | -0.1811 | 2.0792 | |
| SUM149PT | TNBC | Basal B | Gemcitabine | DNA replication | DNA replication | 144 | uM | 9830.011 | 0.1348 | -0.2371 | 2.0792 | |
| SUM159PT | TNBC | Basal B | Gemcitabine | DNA replication | DNA replication | 0.00037 | uM | 7918.011 | 1.1121 | 1.0749 | 2.8897 | |
| SUM159PT | TNBC | Basal B | Gemcitabine | DNA replication | DNA replication | 0.00185 | uM | 7918.011 | 1.1611 | 1.1061 | 2.8897 |