Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SUM159PT | TNBC | Basal B | Gemcitabine | DNA replication | DNA replication | 0.00925 | uM | 7918.011 | 0.7412 | 0.8031 | 2.8897 | |
| SUM159PT | TNBC | Basal B | Gemcitabine | DNA replication | DNA replication | 0.0462 | uM | 7918.011 | 0.2281 | 0.1992 | 2.8897 | |
| SUM159PT | TNBC | Basal B | Gemcitabine | DNA replication | DNA replication | 0.231 | uM | 7918.011 | 0.2257 | 0.1949 | 2.8897 | |
| SUM159PT | TNBC | Basal B | Gemcitabine | DNA replication | DNA replication | 1.16 | uM | 7918.011 | 0.1849 | 0.1153 | 2.8897 | |
| SUM159PT | TNBC | Basal B | Gemcitabine | DNA replication | DNA replication | 5.78 | uM | 7918.011 | 0.2429 | 0.2256 | 2.8897 | |
| SUM159PT | TNBC | Basal B | Gemcitabine | DNA replication | DNA replication | 28.9 | uM | 7918.011 | 0.4037 | 0.4611 | 2.8897 | |
| SUM159PT | TNBC | Basal B | Gemcitabine | DNA replication | DNA replication | 144 | uM | 7918.011 | 0.1806 | 0.1062 | 2.8897 | |
| SUM159PT | TNBC | Basal B | Gemcitabine | DNA replication | DNA replication | 0.00037 | uM | 7919.011 | 1.0189 | 1.0103 | 3.6508 | |
| SUM159PT | TNBC | Basal B | Gemcitabine | DNA replication | DNA replication | 0.00185 | uM | 7919.011 | 1.0051 | 1.0028 | 3.6508 | |
| SUM159PT | TNBC | Basal B | Gemcitabine | DNA replication | DNA replication | 0.00925 | uM | 7919.011 | 0.4932 | 0.6479 | 3.6508 | |
| SUM159PT | TNBC | Basal B | Gemcitabine | DNA replication | DNA replication | 0.0462 | uM | 7919.011 | 0.1522 | 0.1943 | 3.6508 | |
| SUM159PT | TNBC | Basal B | Gemcitabine | DNA replication | DNA replication | 0.231 | uM | 7919.011 | 0.1627 | 0.2163 | 3.6508 | |
| SUM159PT | TNBC | Basal B | Gemcitabine | DNA replication | DNA replication | 1.16 | uM | 7919.011 | 0.1551 | 0.2003 | 3.6508 | |
| SUM159PT | TNBC | Basal B | Gemcitabine | DNA replication | DNA replication | 5.78 | uM | 7919.011 | 0.1363 | 0.1588 | 3.6508 | |
| SUM159PT | TNBC | Basal B | Gemcitabine | DNA replication | DNA replication | 28.9 | uM | 7919.011 | 0.1453 | 0.1791 | 3.6508 | |
| SUM159PT | TNBC | Basal B | Gemcitabine | DNA replication | DNA replication | 144 | uM | 7919.011 | 0.1501 | 0.1898 | 3.6508 | |
| SUM159PT | TNBC | Basal B | Gemcitabine | DNA replication | DNA replication | 0.00185 | uM | 7920.075 | 0.9397 | 0.9730 | 4.5785 | |
| SUM159PT | TNBC | Basal B | Gemcitabine | DNA replication | DNA replication | 0.00924 | uM | 7920.075 | 0.8816 | 0.9457 | 4.5785 | |
| SUM159PT | TNBC | Basal B | Gemcitabine | DNA replication | DNA replication | 0.0462 | uM | 7920.075 | 0.1580 | 0.3366 | 4.5785 | |
| SUM159PT | TNBC | Basal B | Gemcitabine | DNA replication | DNA replication | 0.231 | uM | 7920.075 | 0.0749 | 0.1357 | 4.5785 | |
| SUM159PT | TNBC | Basal B | Gemcitabine | DNA replication | DNA replication | 1.16 | uM | 7920.075 | 0.0593 | 0.0790 | 4.5785 | |
| SUM159PT | TNBC | Basal B | Gemcitabine | DNA replication | DNA replication | 5.78 | uM | 7920.075 | 0.0527 | 0.0517 | 4.5785 | |
| SUM159PT | TNBC | Basal B | Gemcitabine | DNA replication | DNA replication | 28.9 | uM | 7920.075 | 0.0510 | 0.0442 | 4.5785 | |
| SUM159PT | TNBC | Basal B | Gemcitabine | DNA replication | DNA replication | 144 | uM | 7920.075 | 0.0485 | 0.0327 | 4.5785 | |
| SUM159PT | TNBC | Basal B | Gemcitabine | DNA replication | DNA replication | 722 | uM | 7920.075 | 0.0589 | 0.0776 | 4.5785 |