Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SUM185PE | TNBC | Luminal | Gemcitabine | DNA replication | DNA replication | 0.00037 | uM | 7921.011 | 0.9662 | 0.9008 | 0.6757 | |
| SUM185PE | TNBC | Luminal | Gemcitabine | DNA replication | DNA replication | 0.00185 | uM | 7921.011 | 1.0147 | 1.0437 | 0.6757 | |
| SUM185PE | TNBC | Luminal | Gemcitabine | DNA replication | DNA replication | 0.00925 | uM | 7921.011 | 0.9432 | 0.8342 | 0.6757 | |
| SUM185PE | TNBC | Luminal | Gemcitabine | DNA replication | DNA replication | 0.0462 | uM | 7921.011 | 0.9175 | 0.7608 | 0.6757 | |
| SUM185PE | TNBC | Luminal | Gemcitabine | DNA replication | DNA replication | 0.231 | uM | 7921.011 | 0.8378 | 0.5392 | 0.6757 | |
| SUM185PE | TNBC | Luminal | Gemcitabine | DNA replication | DNA replication | 1.16 | uM | 7921.011 | 0.7970 | 0.4296 | 0.6757 | |
| SUM185PE | TNBC | Luminal | Gemcitabine | DNA replication | DNA replication | 5.78 | uM | 7921.011 | 0.7026 | 0.1863 | 0.6757 | |
| SUM185PE | TNBC | Luminal | Gemcitabine | DNA replication | DNA replication | 28.9 | uM | 7921.011 | 0.6912 | 0.1578 | 0.6757 | |
| SUM185PE | TNBC | Luminal | Gemcitabine | DNA replication | DNA replication | 144 | uM | 7921.011 | 0.7567 | 0.3238 | 0.6757 | |
| SUM185PE | TNBC | Luminal | Gemcitabine | DNA replication | DNA replication | 0.000168 | uM | 10146.12 | 1.0727 | 1.1404 | 1.0341 | |
| SUM185PE | TNBC | Luminal | Gemcitabine | DNA replication | DNA replication | 0.00084 | uM | 10146.12 | 0.9932 | 0.9869 | 1.0341 | |
| SUM185PE | TNBC | Luminal | Gemcitabine | DNA replication | DNA replication | 0.0042 | uM | 10146.12 | 1.0285 | 1.0551 | 1.0341 | |
| SUM185PE | TNBC | Luminal | Gemcitabine | DNA replication | DNA replication | 0.021 | uM | 10146.12 | 0.8604 | 0.7294 | 1.0341 | |
| SUM185PE | TNBC | Luminal | Gemcitabine | DNA replication | DNA replication | 0.105 | uM | 10146.12 | 0.7786 | 0.5701 | 1.0341 | |
| SUM185PE | TNBC | Luminal | Gemcitabine | DNA replication | DNA replication | 0.525 | uM | 10146.12 | 0.7496 | 0.5135 | 1.0341 | |
| SUM185PE | TNBC | Luminal | Gemcitabine | DNA replication | DNA replication | 2.62 | uM | 10146.12 | 0.6139 | 0.2477 | 1.0341 | |
| SUM185PE | TNBC | Luminal | Gemcitabine | DNA replication | DNA replication | 13.1 | uM | 10146.12 | 0.5851 | 0.1910 | 1.0341 | |
| SUM185PE | TNBC | Luminal | Gemcitabine | DNA replication | DNA replication | 65.6 | uM | 10146.12 | 0.6842 | 0.3856 | 1.0341 | |
| SUM229PE | TNBC | - | Gemcitabine | DNA replication | DNA replication | 0.00037 | uM | 9860.011 | 1.2126 | 1.2819 | 1.4618 | |
| SUM229PE | TNBC | - | Gemcitabine | DNA replication | DNA replication | 0.00185 | uM | 9860.011 | 1.1340 | 1.1797 | 1.4618 | |
| SUM229PE | TNBC | - | Gemcitabine | DNA replication | DNA replication | 0.00925 | uM | 9860.011 | 1.1833 | 1.2441 | 1.4618 | |
| SUM229PE | TNBC | - | Gemcitabine | DNA replication | DNA replication | 0.0462 | uM | 9860.011 | 0.8053 | 0.7246 | 1.4618 | |
| SUM229PE | TNBC | - | Gemcitabine | DNA replication | DNA replication | 0.231 | uM | 9860.011 | 0.5822 | 0.3814 | 1.4618 | |
| SUM229PE | TNBC | - | Gemcitabine | DNA replication | DNA replication | 1.16 | uM | 9860.011 | 0.5454 | 0.3211 | 1.4618 | |
| SUM229PE | TNBC | - | Gemcitabine | DNA replication | DNA replication | 5.78 | uM | 9860.011 | 0.4802 | 0.2108 | 1.4618 |