Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC3153 | TNBC | Basal A | Glycyl-H-1152 | ROCK2 | 0.0533 | uM | 10937.15 | 0.9818 | 0.9735 | 1.3769 | ||
| HCC3153 | TNBC | Basal A | Glycyl-H-1152 | ROCK2 | 0.267 | uM | 10937.15 | 0.9769 | 0.9663 | 1.3769 | ||
| HCC3153 | TNBC | Basal A | Glycyl-H-1152 | ROCK2 | 1.33 | uM | 10937.15 | 1.0431 | 1.0622 | 1.3769 | ||
| HCC3153 | TNBC | Basal A | Glycyl-H-1152 | ROCK2 | 6.67 | uM | 10937.15 | 0.9172 | 0.8783 | 1.3769 | ||
| HCC3153 | TNBC | Basal A | Glycyl-H-1152 | ROCK2 | 33.3 | uM | 10937.15 | 0.7910 | 0.6869 | 1.3769 | ||
| HCC38 | TNBC | Basal B | Glycyl-H-1152 | ROCK2 | 0.0000853 | uM | 10578.138 | 1.0085 | 1.0095 | 1.7866 | ||
| HCC38 | TNBC | Basal B | Glycyl-H-1152 | ROCK2 | 0.000427 | uM | 10578.138 | 0.8990 | 0.8843 | 1.7866 | ||
| HCC38 | TNBC | Basal B | Glycyl-H-1152 | ROCK2 | 0.00213 | uM | 10578.138 | 0.9674 | 0.9632 | 1.7866 | ||
| HCC38 | TNBC | Basal B | Glycyl-H-1152 | ROCK2 | 0.0107 | uM | 10578.138 | 0.9159 | 0.9040 | 1.7866 | ||
| HCC38 | TNBC | Basal B | Glycyl-H-1152 | ROCK2 | 0.0533 | uM | 10578.138 | 0.9767 | 0.9738 | 1.7866 | ||
| HCC38 | TNBC | Basal B | Glycyl-H-1152 | ROCK2 | 0.267 | uM | 10578.138 | 1.0214 | 1.0238 | 1.7866 | ||
| HCC38 | TNBC | Basal B | Glycyl-H-1152 | ROCK2 | 1.33 | uM | 10578.138 | 0.4080 | 0.2109 | 1.7866 | ||
| HCC38 | TNBC | Basal B | Glycyl-H-1152 | ROCK2 | 6.67 | uM | 10578.138 | 0.3184 | 0.0540 | 1.7866 | ||
| HCC38 | TNBC | Basal B | Glycyl-H-1152 | ROCK2 | 33.3 | uM | 10578.138 | 0.1529 | -0.3009 | 1.7866 | ||
| HCC38 | TNBC | Basal B | Glycyl-H-1152 | ROCK2 | 0.000171 | uM | 11850.16 | 1.0169 | 1.0180 | 1.8797 | ||
| HCC38 | TNBC | Basal B | Glycyl-H-1152 | ROCK2 | 0.000853 | uM | 11850.16 | 1.0036 | 1.0039 | 1.8797 | ||
| HCC38 | TNBC | Basal B | Glycyl-H-1152 | ROCK2 | 0.00427 | uM | 11850.16 | 0.9639 | 0.9613 | 1.8797 | ||
| HCC38 | TNBC | Basal B | Glycyl-H-1152 | ROCK2 | 0.0213 | uM | 11850.16 | 0.9855 | 0.9846 | 1.8797 | ||
| HCC38 | TNBC | Basal B | Glycyl-H-1152 | ROCK2 | 0.107 | uM | 11850.16 | 0.9793 | 0.9779 | 1.8797 | ||
| HCC38 | TNBC | Basal B | Glycyl-H-1152 | ROCK2 | 0.533 | uM | 11850.16 | 0.8305 | 0.8119 | 1.8797 | ||
| HCC38 | TNBC | Basal B | Glycyl-H-1152 | ROCK2 | 2.67 | uM | 11850.16 | 0.2311 | -0.0826 | 1.8797 | ||
| HCC38 | TNBC | Basal B | Glycyl-H-1152 | ROCK2 | 13.3 | uM | 11850.16 | 0.1406 | -0.2957 | 1.8797 | ||
| HCC38 | TNBC | Basal B | Glycyl-H-1152 | ROCK2 | 66.7 | uM | 11850.16 | 0.0768 | -0.4893 | 1.8797 | ||
| HCC70 | TNBC | Basal A | Glycyl-H-1152 | ROCK2 | 0.0000853 | uM | 10873.15 | 1.0537 | 1.0894 | 1.1958 | ||
| HCC70 | TNBC | Basal A | Glycyl-H-1152 | ROCK2 | 0.000427 | uM | 10873.15 | 1.0621 | 1.1034 | 1.1958 |