Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC1806 | TNBC | Basal A | Glycyl-H-1152 | ROCK2 | 66.7 | uM | 12239.16 | 0.7369 | 0.6981 | 1.8654 | ||
| HCC1937 | TNBC | Basal A | Glycyl-H-1152 | ROCK2 | 0.000171 | uM | 11849.16 | 0.9602 | 0.9341 | 1.2119 | ||
| HCC1937 | TNBC | Basal A | Glycyl-H-1152 | ROCK2 | 0.000853 | uM | 11849.16 | 1.0259 | 1.0427 | 1.2119 | ||
| HCC1937 | TNBC | Basal A | Glycyl-H-1152 | ROCK2 | 0.00427 | uM | 11849.16 | 0.9660 | 0.9438 | 1.2119 | ||
| HCC1937 | TNBC | Basal A | Glycyl-H-1152 | ROCK2 | 0.0213 | uM | 11849.16 | 1.0396 | 1.0652 | 1.2119 | ||
| HCC1937 | TNBC | Basal A | Glycyl-H-1152 | ROCK2 | 0.107 | uM | 11849.16 | 0.9625 | 0.9379 | 1.2119 | ||
| HCC1937 | TNBC | Basal A | Glycyl-H-1152 | ROCK2 | 0.533 | uM | 11849.16 | 1.0562 | 1.0923 | 1.2119 | ||
| HCC1937 | TNBC | Basal A | Glycyl-H-1152 | ROCK2 | 2.67 | uM | 11849.16 | 1.0427 | 1.0701 | 1.2119 | ||
| HCC1937 | TNBC | Basal A | Glycyl-H-1152 | ROCK2 | 13.3 | uM | 11849.16 | 0.8905 | 0.8175 | 1.2119 | ||
| HCC1937 | TNBC | Basal A | Glycyl-H-1152 | ROCK2 | 66.7 | uM | 11849.16 | 0.7470 | 0.5722 | 1.2119 | ||
| HCC1954 | HER2amp | Basal A | Glycyl-H-1152 | ROCK2 | 0.0000853 | uM | 11055.15 | 1.0594 | 1.0716 | 1.6412 | ||
| HCC1954 | HER2amp | Basal A | Glycyl-H-1152 | ROCK2 | 0.000427 | uM | 11055.15 | 1.0828 | 1.0993 | 1.6412 | ||
| HCC1954 | HER2amp | Basal A | Glycyl-H-1152 | ROCK2 | 0.00213 | uM | 11055.15 | 1.0494 | 1.0597 | 1.6412 | ||
| HCC1954 | HER2amp | Basal A | Glycyl-H-1152 | ROCK2 | 0.0107 | uM | 11055.15 | 1.0962 | 1.1152 | 1.6412 | ||
| HCC1954 | HER2amp | Basal A | Glycyl-H-1152 | ROCK2 | 0.0533 | uM | 11055.15 | 1.0723 | 1.0869 | 1.6412 | ||
| HCC1954 | HER2amp | Basal A | Glycyl-H-1152 | ROCK2 | 0.267 | uM | 11055.15 | 1.0291 | 1.0353 | 1.6412 | ||
| HCC1954 | HER2amp | Basal A | Glycyl-H-1152 | ROCK2 | 1.33 | uM | 11055.15 | 1.0255 | 1.0309 | 1.6412 | ||
| HCC1954 | HER2amp | Basal A | Glycyl-H-1152 | ROCK2 | 6.67 | uM | 11055.15 | 0.9298 | 0.9133 | 1.6412 | ||
| HCC1954 | HER2amp | Basal A | Glycyl-H-1152 | ROCK2 | 33.3 | uM | 11055.15 | 0.9149 | 0.8945 | 1.6412 | ||
| HCC2185 | TNBC | Luminal | Glycyl-H-1152 | ROCK2 | 0.0000853 | uM | 10996.15 | 0.9360 | 0.7565 | 0.5092 | ||
| HCC2185 | TNBC | Luminal | Glycyl-H-1152 | ROCK2 | 0.000427 | uM | 10996.15 | 1.0080 | 1.0316 | 0.5092 | ||
| HCC2185 | TNBC | Luminal | Glycyl-H-1152 | ROCK2 | 0.00213 | uM | 10996.15 | 1.0291 | 1.1161 | 0.5092 | ||
| HCC2185 | TNBC | Luminal | Glycyl-H-1152 | ROCK2 | 0.0107 | uM | 10996.15 | 1.0881 | 1.3607 | 0.5092 | ||
| HCC2185 | TNBC | Luminal | Glycyl-H-1152 | ROCK2 | 0.0533 | uM | 10996.15 | 0.9873 | 0.9505 | 0.5092 | ||
| HCC2185 | TNBC | Luminal | Glycyl-H-1152 | ROCK2 | 0.267 | uM | 10996.15 | 1.0407 | 1.1631 | 0.5092 |