Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MDA-MB-361 | HER2amp | Luminal | Glycyl-H-1152 | ROCK2 | 1.33 | uM | 10999.15 | 0.9718 | 0.9291 | 0.7928 | ||
| MDA-MB-361 | HER2amp | Luminal | Glycyl-H-1152 | ROCK2 | 6.67 | uM | 10999.15 | 0.8986 | 0.7476 | 0.7928 | ||
| MDA-MB-361 | HER2amp | Luminal | Glycyl-H-1152 | ROCK2 | 33.3 | uM | 10999.15 | 0.8136 | 0.5417 | 0.7928 | ||
| MDA-MB-361 | HER2amp | Luminal | Glycyl-H-1152 | ROCK2 | 0.000171 | uM | 12379.169 | 0.9988 | 0.9959 | 0.5957 | ||
| MDA-MB-361 | HER2amp | Luminal | Glycyl-H-1152 | ROCK2 | 0.000853 | uM | 12379.169 | 1.0310 | 1.1053 | 0.5957 | ||
| MDA-MB-361 | HER2amp | Luminal | Glycyl-H-1152 | ROCK2 | 0.00427 | uM | 12379.169 | 0.9897 | 0.9655 | 0.5957 | ||
| MDA-MB-361 | HER2amp | Luminal | Glycyl-H-1152 | ROCK2 | 0.0213 | uM | 12379.169 | 1.0492 | 1.1678 | 0.5957 | ||
| MDA-MB-361 | HER2amp | Luminal | Glycyl-H-1152 | ROCK2 | 0.107 | uM | 12379.169 | 1.0305 | 1.1033 | 0.5957 | ||
| MDA-MB-361 | HER2amp | Luminal | Glycyl-H-1152 | ROCK2 | 0.533 | uM | 12379.169 | 1.0929 | 1.3216 | 0.5957 | ||
| MDA-MB-361 | HER2amp | Luminal | Glycyl-H-1152 | ROCK2 | 2.67 | uM | 12379.169 | 0.9844 | 0.9478 | 0.5957 | ||
| MDA-MB-361 | HER2amp | Luminal | Glycyl-H-1152 | ROCK2 | 13.3 | uM | 12379.169 | 0.9968 | 0.9893 | 0.5957 | ||
| MDA-MB-361 | HER2amp | Luminal | Glycyl-H-1152 | ROCK2 | 66.7 | uM | 12379.169 | 0.9305 | 0.7722 | 0.5957 | ||
| MDA-MB-415 | HR+ | Luminal | Glycyl-H-1152 | ROCK2 | 0.0000853 | uM | 10938.15 | 0.8985 | 0.8058 | 1.0480 | ||
| MDA-MB-415 | HR+ | Luminal | Glycyl-H-1152 | ROCK2 | 0.000427 | uM | 10938.15 | 0.8162 | 0.6476 | 1.0480 | ||
| MDA-MB-415 | HR+ | Luminal | Glycyl-H-1152 | ROCK2 | 0.00213 | uM | 10938.15 | 0.8627 | 0.7371 | 1.0480 | ||
| MDA-MB-415 | HR+ | Luminal | Glycyl-H-1152 | ROCK2 | 0.0107 | uM | 10938.15 | 0.8438 | 0.7008 | 1.0480 | ||
| MDA-MB-415 | HR+ | Luminal | Glycyl-H-1152 | ROCK2 | 0.0533 | uM | 10938.15 | 0.8435 | 0.7001 | 1.0480 | ||
| MDA-MB-415 | HR+ | Luminal | Glycyl-H-1152 | ROCK2 | 0.267 | uM | 10938.15 | 0.8686 | 0.7485 | 1.0480 | ||
| MDA-MB-415 | HR+ | Luminal | Glycyl-H-1152 | ROCK2 | 1.33 | uM | 10938.15 | 0.8254 | 0.6654 | 1.0480 | ||
| MDA-MB-415 | HR+ | Luminal | Glycyl-H-1152 | ROCK2 | 6.67 | uM | 10938.15 | 0.7816 | 0.5809 | 1.0480 | ||
| MDA-MB-415 | HR+ | Luminal | Glycyl-H-1152 | ROCK2 | 33.3 | uM | 10938.15 | 0.6203 | 0.2679 | 1.0480 | ||
| MDA-MB-415 | HR+ | Luminal | Glycyl-H-1152 | ROCK2 | 0.000171 | uM | 12333.169 | 0.9713 | 0.8974 | 0.5536 | ||
| MDA-MB-415 | HR+ | Luminal | Glycyl-H-1152 | ROCK2 | 0.000853 | uM | 12333.169 | 0.9749 | 0.9103 | 0.5536 | ||
| MDA-MB-415 | HR+ | Luminal | Glycyl-H-1152 | ROCK2 | 0.00427 | uM | 12333.169 | 0.8907 | 0.6227 | 0.5536 | ||
| MDA-MB-415 | HR+ | Luminal | Glycyl-H-1152 | ROCK2 | 0.0213 | uM | 12333.169 | 1.0261 | 1.0953 | 0.5536 |