Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SUM1315MO2 | TNBC | Basal B | Glycyl-H-1152 | ROCK2 | 0.0000853 | uM | 10875.15 | 0.9495 | 0.8822 | 0.8527 | ||
| SUM1315MO2 | TNBC | Basal B | Glycyl-H-1152 | ROCK2 | 0.000427 | uM | 10875.15 | 0.9900 | 0.9766 | 0.8527 | ||
| SUM1315MO2 | TNBC | Basal B | Glycyl-H-1152 | ROCK2 | 0.00213 | uM | 10875.15 | 0.9907 | 0.9783 | 0.8527 | ||
| SUM1315MO2 | TNBC | Basal B | Glycyl-H-1152 | ROCK2 | 0.0107 | uM | 10875.15 | 1.0213 | 1.0501 | 0.8527 | ||
| SUM1315MO2 | TNBC | Basal B | Glycyl-H-1152 | ROCK2 | 0.0533 | uM | 10875.15 | 0.9495 | 0.8822 | 0.8527 | ||
| SUM1315MO2 | TNBC | Basal B | Glycyl-H-1152 | ROCK2 | 0.267 | uM | 10875.15 | 0.9570 | 0.8996 | 0.8527 | ||
| SUM1315MO2 | TNBC | Basal B | Glycyl-H-1152 | ROCK2 | 1.33 | uM | 10875.15 | 0.9084 | 0.7870 | 0.8527 | ||
| SUM1315MO2 | TNBC | Basal B | Glycyl-H-1152 | ROCK2 | 6.67 | uM | 10875.15 | 0.7120 | 0.3429 | 0.8527 | ||
| SUM1315MO2 | TNBC | Basal B | Glycyl-H-1152 | ROCK2 | 33.3 | uM | 10875.15 | 0.5054 | -0.1016 | 0.8527 | ||
| SUM1315MO2 | TNBC | Basal B | Glycyl-H-1152 | ROCK2 | 0.000171 | uM | 12428.169 | 1.0189 | 1.0484 | 0.7851 | ||
| SUM1315MO2 | TNBC | Basal B | Glycyl-H-1152 | ROCK2 | 0.000853 | uM | 12428.169 | 0.9460 | 0.8636 | 0.7851 | ||
| SUM1315MO2 | TNBC | Basal B | Glycyl-H-1152 | ROCK2 | 0.00427 | uM | 12428.169 | 0.9963 | 0.9906 | 0.7851 | ||
| SUM1315MO2 | TNBC | Basal B | Glycyl-H-1152 | ROCK2 | 0.0213 | uM | 12428.169 | 0.9414 | 0.8520 | 0.7851 | ||
| SUM1315MO2 | TNBC | Basal B | Glycyl-H-1152 | ROCK2 | 0.107 | uM | 12428.169 | 1.0425 | 1.1088 | 0.7851 | ||
| SUM1315MO2 | TNBC | Basal B | Glycyl-H-1152 | ROCK2 | 0.533 | uM | 12428.169 | 0.9709 | 0.9261 | 0.7851 | ||
| SUM1315MO2 | TNBC | Basal B | Glycyl-H-1152 | ROCK2 | 2.67 | uM | 12428.169 | 0.8795 | 0.6982 | 0.7851 | ||
| SUM1315MO2 | TNBC | Basal B | Glycyl-H-1152 | ROCK2 | 13.3 | uM | 12428.169 | 0.7853 | 0.4701 | 0.7851 | ||
| SUM1315MO2 | TNBC | Basal B | Glycyl-H-1152 | ROCK2 | 66.7 | uM | 12428.169 | 0.6781 | 0.2193 | 0.7851 | ||
| SUM149PT | TNBC | Basal B | Glycyl-H-1152 | ROCK2 | 0.0000853 | uM | 10819.15 | 1.0243 | 1.0227 | 2.1256 | ||
| SUM149PT | TNBC | Basal B | Glycyl-H-1152 | ROCK2 | 0.000427 | uM | 10819.15 | 0.9548 | 0.9569 | 2.1256 | ||
| SUM149PT | TNBC | Basal B | Glycyl-H-1152 | ROCK2 | 0.00213 | uM | 10819.15 | 0.9733 | 0.9747 | 2.1256 | ||
| SUM149PT | TNBC | Basal B | Glycyl-H-1152 | ROCK2 | 0.0107 | uM | 10819.15 | 0.9453 | 0.9477 | 2.1256 | ||
| SUM149PT | TNBC | Basal B | Glycyl-H-1152 | ROCK2 | 0.0533 | uM | 10819.15 | 1.0012 | 1.0011 | 2.1256 | ||
| SUM149PT | TNBC | Basal B | Glycyl-H-1152 | ROCK2 | 0.267 | uM | 10819.15 | 0.9625 | 0.9643 | 2.1256 | ||
| SUM149PT | TNBC | Basal B | Glycyl-H-1152 | ROCK2 | 1.33 | uM | 10819.15 | 0.9129 | 0.9160 | 2.1256 |