Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC1143 | TNBC | Basal A | Etoposide | TOP2 | TOP | 0.00427 | uM | 7430.074 | 0.9882 | 0.9860 | 1.6943 | |
| HCC1143 | TNBC | Basal A | Etoposide | TOP2 | TOP | 0.0213 | uM | 7430.074 | 1.0539 | 1.0630 | 1.6943 | |
| HCC1143 | TNBC | Basal A | Etoposide | TOP2 | TOP | 0.107 | uM | 7430.074 | 1.0105 | 1.0124 | 1.6943 | |
| HCC1143 | TNBC | Basal A | Etoposide | TOP2 | TOP | 0.533 | uM | 7430.074 | 0.9055 | 0.8862 | 1.6943 | |
| HCC1143 | TNBC | Basal A | Etoposide | TOP2 | TOP | 2.67 | uM | 7430.074 | 0.7634 | 0.7054 | 1.6943 | |
| HCC1143 | TNBC | Basal A | Etoposide | TOP2 | TOP | 13.3 | uM | 7430.074 | 0.4549 | 0.2564 | 1.6943 | |
| HCC1143 | TNBC | Basal A | Etoposide | TOP2 | TOP | 66.7 | uM | 7430.074 | 0.2213 | -0.1788 | 1.6943 | |
| HCC1143 | TNBC | Basal A | Etoposide | TOP2 | TOP | 333 | uM | 7430.074 | 0.1148 | -0.4426 | 1.6943 | |
| HCC1187 | TNBC | Basal A | Etoposide | TOP2 | TOP | 0.000853 | uM | 7431.074 | 1.0171 | 1.0238 | 1.4349 | |
| HCC1187 | TNBC | Basal A | Etoposide | TOP2 | TOP | 0.00427 | uM | 7431.074 | 1.0108 | 1.0150 | 1.4349 | |
| HCC1187 | TNBC | Basal A | Etoposide | TOP2 | TOP | 0.0213 | uM | 7431.074 | 1.0176 | 1.0244 | 1.4349 | |
| HCC1187 | TNBC | Basal A | Etoposide | TOP2 | TOP | 0.107 | uM | 7431.074 | 0.8984 | 0.8561 | 1.4349 | |
| HCC1187 | TNBC | Basal A | Etoposide | TOP2 | TOP | 0.533 | uM | 7431.074 | 0.7684 | 0.6646 | 1.4349 | |
| HCC1187 | TNBC | Basal A | Etoposide | TOP2 | TOP | 2.67 | uM | 7431.074 | 0.5123 | 0.2549 | 1.4349 | |
| HCC1187 | TNBC | Basal A | Etoposide | TOP2 | TOP | 13.3 | uM | 7431.074 | 0.0752 | -0.6706 | 1.4349 | |
| HCC1187 | TNBC | Basal A | Etoposide | TOP2 | TOP | 66.7 | uM | 7431.074 | 0.0691 | -0.6895 | 1.4349 | |
| HCC1187 | TNBC | Basal A | Etoposide | TOP2 | TOP | 333 | uM | 7431.074 | 0.0147 | -0.8942 | 1.4349 | |
| HCC1187 | TNBC | Basal A | Etoposide | TOP2 | TOP | 0.000853 | uM | 7432.074 | 1.0310 | 1.0724 | 0.8598 | |
| HCC1187 | TNBC | Basal A | Etoposide | TOP2 | TOP | 0.00427 | uM | 7432.074 | 1.0352 | 1.0822 | 0.8598 | |
| HCC1187 | TNBC | Basal A | Etoposide | TOP2 | TOP | 0.0213 | uM | 7432.074 | 1.0682 | 1.1595 | 0.8598 | |
| HCC1187 | TNBC | Basal A | Etoposide | TOP2 | TOP | 0.107 | uM | 7432.074 | 0.8533 | 0.6631 | 0.8598 | |
| HCC1187 | TNBC | Basal A | Etoposide | TOP2 | TOP | 0.533 | uM | 7432.074 | 0.5805 | 0.0624 | 0.8598 | |
| HCC1187 | TNBC | Basal A | Etoposide | TOP2 | TOP | 2.67 | uM | 7432.074 | 0.6567 | 0.2263 | 0.8598 | |
| HCC1187 | TNBC | Basal A | Etoposide | TOP2 | TOP | 13.3 | uM | 7432.074 | 0.0907 | -0.8774 | 0.8598 | |
| HCC1187 | TNBC | Basal A | Etoposide | TOP2 | TOP | 66.7 | uM | 7432.074 | 0.0731 | -0.9046 | 0.8598 |