Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset - HMS LINCS Database

Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)

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Small molecules	Cells	Antibodies

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Cell	Clinical Subtype	Transcriptional Subtype	Small Molecule	Perturbagen Target	Perturbagen Class	Perturbagen Concentration	Perturbagen Conc Unit	Biological Replicate ID	Relative Cell Count	Normalized Growth Rate Inhibition Value	Nominal Division Rate
MDA-MB-361	HER2amp	Luminal	FR180204	ERK1/2	MAPK	33.3	uM	10643.137	0.9116	0.7332	0.6468
MDA-MB-361	HER2amp	Luminal	FR180204	ERK1/2	MAPK	0.0000853	uM	10999.149	0.9864	0.9626	0.7265
MDA-MB-361	HER2amp	Luminal	FR180204	ERK1/2	MAPK	0.000427	uM	10999.149	0.9983	0.9952	0.7265
MDA-MB-361	HER2amp	Luminal	FR180204	ERK1/2	MAPK	0.00213	uM	10999.149	1.0102	1.0282	0.7265
MDA-MB-361	HER2amp	Luminal	FR180204	ERK1/2	MAPK	0.0107	uM	10999.149	0.9855	0.9601	0.7265
MDA-MB-361	HER2amp	Luminal	FR180204	ERK1/2	MAPK	0.0533	uM	10999.149	1.0244	1.0676	0.7265
MDA-MB-361	HER2amp	Luminal	FR180204	ERK1/2	MAPK	0.267	uM	10999.149	0.9753	0.9322	0.7265
MDA-MB-361	HER2amp	Luminal	FR180204	ERK1/2	MAPK	1.33	uM	10999.149	1.0019	1.0052	0.7265
MDA-MB-361	HER2amp	Luminal	FR180204	ERK1/2	MAPK	6.67	uM	10999.149	0.9186	0.7793	0.7265
MDA-MB-361	HER2amp	Luminal	FR180204	ERK1/2	MAPK	33.3	uM	10999.149	0.8741	0.6617	0.7265
MDA-MB-415	HR+	Luminal	FR180204	ERK1/2	MAPK	0.0000853	uM	10938.149	0.8604	0.7210	1.0006
MDA-MB-415	HR+	Luminal	FR180204	ERK1/2	MAPK	0.000427	uM	10938.149	0.8775	0.7552	1.0006
MDA-MB-415	HR+	Luminal	FR180204	ERK1/2	MAPK	0.00213	uM	10938.149	0.7261	0.4526	1.0006
MDA-MB-415	HR+	Luminal	FR180204	ERK1/2	MAPK	0.0107	uM	10938.149	0.9178	0.8358	1.0006
MDA-MB-415	HR+	Luminal	FR180204	ERK1/2	MAPK	0.0533	uM	10938.149	1.0007	1.0014	1.0006
MDA-MB-415	HR+	Luminal	FR180204	ERK1/2	MAPK	0.267	uM	10938.149	0.8877	0.7755	1.0006
MDA-MB-415	HR+	Luminal	FR180204	ERK1/2	MAPK	1.33	uM	10938.149	1.0023	1.0046	1.0006
MDA-MB-415	HR+	Luminal	FR180204	ERK1/2	MAPK	6.67	uM	10938.149	0.9896	0.9792	1.0006
MDA-MB-415	HR+	Luminal	FR180204	ERK1/2	MAPK	33.3	uM	10938.149	0.9292	0.8584	1.0006
MDA-MB-415	HR+	Luminal	FR180204	ERK1/2	MAPK	0.000256	uM	12333.166	0.9193	0.7519	0.6353
MDA-MB-415	HR+	Luminal	FR180204	ERK1/2	MAPK	0.00128	uM	12333.166	0.8692	0.6040	0.6353
MDA-MB-415	HR+	Luminal	FR180204	ERK1/2	MAPK	0.0064	uM	12333.166	0.9969	0.9902	0.6353
MDA-MB-415	HR+	Luminal	FR180204	ERK1/2	MAPK	0.032	uM	12333.166	0.8652	0.5923	0.6353
MDA-MB-415	HR+	Luminal	FR180204	ERK1/2	MAPK	0.16	uM	12333.166	0.9735	0.9173	0.6353
MDA-MB-415	HR+	Luminal	FR180204	ERK1/2	MAPK	0.8	uM	12333.166	0.8814	0.6395	0.6353

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HMS LINCS Project

Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)