Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SUM52PE | HR+ | Luminal | Erlotinib | EGFR | ErbB | 0.0213 | uM | 7541.091 | 0.9914 | 0.9877 | 1.4119 | |
| SUM52PE | HR+ | Luminal | Erlotinib | EGFR | ErbB | 0.107 | uM | 7541.091 | 1.0410 | 1.0578 | 1.4119 | |
| SUM52PE | HR+ | Luminal | Erlotinib | EGFR | ErbB | 0.533 | uM | 7541.091 | 1.0547 | 1.0768 | 1.4119 | |
| SUM52PE | HR+ | Luminal | Erlotinib | EGFR | ErbB | 2.67 | uM | 7541.091 | 0.9834 | 0.9764 | 1.4119 | |
| SUM52PE | HR+ | Luminal | Erlotinib | EGFR | ErbB | 13.3 | uM | 7541.091 | 0.9582 | 0.9404 | 1.4119 | |
| SUM52PE | HR+ | Luminal | Erlotinib | EGFR | ErbB | 66.7 | uM | 7541.091 | 0.5983 | 0.3900 | 1.4119 | |
| T47D | HR+ | Luminal | Erlotinib | EGFR | ErbB | 0.0000853 | uM | 7542.092 | 0.9906 | 0.9878 | 1.5380 | |
| T47D | HR+ | Luminal | Erlotinib | EGFR | ErbB | 0.000427 | uM | 7542.092 | 1.0198 | 1.0256 | 1.5380 | |
| T47D | HR+ | Luminal | Erlotinib | EGFR | ErbB | 0.00213 | uM | 7542.092 | 0.9276 | 0.9047 | 1.5380 | |
| T47D | HR+ | Luminal | Erlotinib | EGFR | ErbB | 0.0107 | uM | 7542.092 | 0.9595 | 0.9470 | 1.5380 | |
| T47D | HR+ | Luminal | Erlotinib | EGFR | ErbB | 0.0533 | uM | 7542.092 | 0.9426 | 0.9245 | 1.5380 | |
| T47D | HR+ | Luminal | Erlotinib | EGFR | ErbB | 0.267 | uM | 7542.092 | 0.9298 | 0.9076 | 1.5380 | |
| T47D | HR+ | Luminal | Erlotinib | EGFR | ErbB | 1.33 | uM | 7542.092 | 1.0589 | 1.0759 | 1.5380 | |
| T47D | HR+ | Luminal | Erlotinib | EGFR | ErbB | 6.67 | uM | 7542.092 | 0.9233 | 0.8988 | 1.5380 | |
| T47D | HR+ | Luminal | Erlotinib | EGFR | ErbB | 33.3 | uM | 7542.092 | 0.8033 | 0.7345 | 1.5380 | |
| T47D | HR+ | Luminal | Erlotinib | EGFR | ErbB | 0.000171 | uM | 7543.091 | 0.9933 | 0.9909 | 1.4781 | |
| T47D | HR+ | Luminal | Erlotinib | EGFR | ErbB | 0.000853 | uM | 7543.091 | 0.9864 | 0.9816 | 1.4781 | |
| T47D | HR+ | Luminal | Erlotinib | EGFR | ErbB | 0.00427 | uM | 7543.091 | 0.9566 | 0.9408 | 1.4781 | |
| T47D | HR+ | Luminal | Erlotinib | EGFR | ErbB | 0.0213 | uM | 7543.091 | 0.9868 | 0.9822 | 1.4781 | |
| T47D | HR+ | Luminal | Erlotinib | EGFR | ErbB | 0.107 | uM | 7543.091 | 0.9579 | 0.9426 | 1.4781 | |
| T47D | HR+ | Luminal | Erlotinib | EGFR | ErbB | 0.533 | uM | 7543.091 | 0.9496 | 0.9312 | 1.4781 | |
| T47D | HR+ | Luminal | Erlotinib | EGFR | ErbB | 2.67 | uM | 7543.091 | 0.9666 | 0.9545 | 1.4781 | |
| T47D | HR+ | Luminal | Erlotinib | EGFR | ErbB | 13.3 | uM | 7543.091 | 0.8955 | 0.8561 | 1.4781 | |
| T47D | HR+ | Luminal | Erlotinib | EGFR | ErbB | 66.7 | uM | 7543.091 | 0.7727 | 0.6798 | 1.4781 | |
| T47DKBLUC | Unknown | Unknown | Erlotinib | EGFR | ErbB | 0.0000853 | uM | 7544.092 | 0.9984 | 0.9971 | 1.1147 |