Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MDA-MB-361 | HER2amp | Luminal | Erlotinib | EGFR | ErbB | 0.533 | uM | 7505.09 | 1.0072 | 1.0229 | 0.6295 | |
| MDA-MB-361 | HER2amp | Luminal | Erlotinib | EGFR | ErbB | 2.67 | uM | 7505.09 | 1.0224 | 1.0716 | 0.6295 | |
| MDA-MB-361 | HER2amp | Luminal | Erlotinib | EGFR | ErbB | 13.3 | uM | 7505.09 | 0.8515 | 0.5491 | 0.6295 | |
| MDA-MB-361 | HER2amp | Luminal | Erlotinib | EGFR | ErbB | 66.7 | uM | 7505.09 | 0.8523 | 0.5515 | 0.6295 | |
| MDA-MB-361 | HER2amp | Luminal | Erlotinib | EGFR | ErbB | 0.000171 | uM | 7506.091 | 1.0348 | 1.0626 | 1.1096 | |
| MDA-MB-361 | HER2amp | Luminal | Erlotinib | EGFR | ErbB | 0.000853 | uM | 7506.091 | 1.0232 | 1.0418 | 1.1096 | |
| MDA-MB-361 | HER2amp | Luminal | Erlotinib | EGFR | ErbB | 0.00427 | uM | 7506.091 | 0.9924 | 0.9863 | 1.1096 | |
| MDA-MB-361 | HER2amp | Luminal | Erlotinib | EGFR | ErbB | 0.0213 | uM | 7506.091 | 1.0526 | 1.0946 | 1.1096 | |
| MDA-MB-361 | HER2amp | Luminal | Erlotinib | EGFR | ErbB | 0.107 | uM | 7506.091 | 0.9637 | 0.9344 | 1.1096 | |
| MDA-MB-361 | HER2amp | Luminal | Erlotinib | EGFR | ErbB | 0.533 | uM | 7506.091 | 1.0316 | 1.0569 | 1.1096 | |
| MDA-MB-361 | HER2amp | Luminal | Erlotinib | EGFR | ErbB | 2.67 | uM | 7506.091 | 1.0250 | 1.0450 | 1.1096 | |
| MDA-MB-361 | HER2amp | Luminal | Erlotinib | EGFR | ErbB | 13.3 | uM | 7506.091 | 0.8370 | 0.7038 | 1.1096 | |
| MDA-MB-361 | HER2amp | Luminal | Erlotinib | EGFR | ErbB | 66.7 | uM | 7506.091 | 0.7424 | 0.5290 | 1.1096 | |
| MDA-MB-361 | HER2amp | Luminal | Erlotinib | EGFR | ErbB | 0.000171 | uM | 7507.09 | 1.0188 | 1.0372 | 1.0118 | |
| MDA-MB-361 | HER2amp | Luminal | Erlotinib | EGFR | ErbB | 0.000853 | uM | 7507.09 | 1.0047 | 1.0092 | 1.0118 | |
| MDA-MB-361 | HER2amp | Luminal | Erlotinib | EGFR | ErbB | 0.00427 | uM | 7507.09 | 1.0193 | 1.0381 | 1.0118 | |
| MDA-MB-361 | HER2amp | Luminal | Erlotinib | EGFR | ErbB | 0.0213 | uM | 7507.09 | 1.0071 | 1.0141 | 1.0118 | |
| MDA-MB-361 | HER2amp | Luminal | Erlotinib | EGFR | ErbB | 0.107 | uM | 7507.09 | 0.9878 | 0.9759 | 1.0118 | |
| MDA-MB-361 | HER2amp | Luminal | Erlotinib | EGFR | ErbB | 0.533 | uM | 7507.09 | 0.9926 | 0.9854 | 1.0118 | |
| MDA-MB-361 | HER2amp | Luminal | Erlotinib | EGFR | ErbB | 2.67 | uM | 7507.09 | 0.9850 | 0.9704 | 1.0118 | |
| MDA-MB-361 | HER2amp | Luminal | Erlotinib | EGFR | ErbB | 13.3 | uM | 7507.09 | 0.9397 | 0.8807 | 1.0118 | |
| MDA-MB-361 | HER2amp | Luminal | Erlotinib | EGFR | ErbB | 66.7 | uM | 7507.09 | 0.7581 | 0.5210 | 1.0118 | |
| MDA-MB-361 | HER2amp | Luminal | Erlotinib | EGFR | ErbB | 0.000171 | uM | 7508.091 | 1.0040 | 1.0120 | 0.6662 | |
| MDA-MB-361 | HER2amp | Luminal | Erlotinib | EGFR | ErbB | 0.000853 | uM | 7508.091 | 1.0045 | 1.0136 | 0.6662 | |
| MDA-MB-361 | HER2amp | Luminal | Erlotinib | EGFR | ErbB | 0.00427 | uM | 7508.091 | 0.9966 | 0.9897 | 0.6662 |