Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| CAMA-1 | HR+ | Luminal | Etoposide | TOP2 | TOP | 0.107 | uM | 5911.074 | 0.8948 | 0.8130 | 1.1317 | |
| CAMA-1 | HR+ | Luminal | Etoposide | TOP2 | TOP | 0.533 | uM | 5911.074 | 0.8595 | 0.7495 | 1.1317 | |
| CAMA-1 | HR+ | Luminal | Etoposide | TOP2 | TOP | 2.67 | uM | 5911.074 | 0.8058 | 0.6526 | 1.1317 | |
| CAMA-1 | HR+ | Luminal | Etoposide | TOP2 | TOP | 13.3 | uM | 5911.074 | 0.4931 | 0.0707 | 1.1317 | |
| CAMA-1 | HR+ | Luminal | Etoposide | TOP2 | TOP | 66.7 | uM | 5911.074 | 0.3152 | -0.2790 | 1.1317 | |
| CAMA-1 | HR+ | Luminal | Etoposide | TOP2 | TOP | 333 | uM | 5911.074 | 0.2811 | -0.3484 | 1.1317 | |
| CAMA-1 | HR+ | Luminal | Etoposide | TOP2 | TOP | 0.000853 | uM | 5912.074 | 1.0429 | 1.0929 | 0.9249 | |
| CAMA-1 | HR+ | Luminal | Etoposide | TOP2 | TOP | 0.00427 | uM | 5912.074 | 0.9806 | 0.9581 | 0.9249 | |
| CAMA-1 | HR+ | Luminal | Etoposide | TOP2 | TOP | 0.0213 | uM | 5912.074 | 1.0310 | 1.0671 | 0.9249 | |
| CAMA-1 | HR+ | Luminal | Etoposide | TOP2 | TOP | 0.107 | uM | 5912.074 | 0.9702 | 0.9356 | 0.9249 | |
| CAMA-1 | HR+ | Luminal | Etoposide | TOP2 | TOP | 0.533 | uM | 5912.074 | 0.9583 | 0.9100 | 0.9249 | |
| CAMA-1 | HR+ | Luminal | Etoposide | TOP2 | TOP | 2.67 | uM | 5912.074 | 0.9128 | 0.8122 | 0.9249 | |
| CAMA-1 | HR+ | Luminal | Etoposide | TOP2 | TOP | 13.3 | uM | 5912.074 | 0.5236 | -0.0065 | 0.9249 | |
| CAMA-1 | HR+ | Luminal | Etoposide | TOP2 | TOP | 66.7 | uM | 5912.074 | 0.3272 | -0.4023 | 0.9249 | |
| CAMA-1 | HR+ | Luminal | Etoposide | TOP2 | TOP | 333 | uM | 5912.074 | 0.2668 | -0.5207 | 0.9249 | |
| HBL-100 | Unknown | Unknown | Etoposide | TOP2 | TOP | 0.000853 | uM | 7429.074 | 1.0130 | 1.0111 | 2.3375 | |
| HBL-100 | Unknown | Unknown | Etoposide | TOP2 | TOP | 0.00427 | uM | 7429.074 | 1.0622 | 1.0523 | 2.3375 | |
| HBL-100 | Unknown | Unknown | Etoposide | TOP2 | TOP | 0.0213 | uM | 7429.074 | 0.9560 | 0.9618 | 2.3375 | |
| HBL-100 | Unknown | Unknown | Etoposide | TOP2 | TOP | 0.107 | uM | 7429.074 | 0.9861 | 0.9881 | 2.3375 | |
| HBL-100 | Unknown | Unknown | Etoposide | TOP2 | TOP | 0.533 | uM | 7429.074 | 0.8807 | 0.8942 | 2.3375 | |
| HBL-100 | Unknown | Unknown | Etoposide | TOP2 | TOP | 2.67 | uM | 7429.074 | 0.5292 | 0.5233 | 2.3375 | |
| HBL-100 | Unknown | Unknown | Etoposide | TOP2 | TOP | 13.3 | uM | 7429.074 | 0.0606 | -0.3973 | 2.3375 | |
| HBL-100 | Unknown | Unknown | Etoposide | TOP2 | TOP | 66.7 | uM | 7429.074 | 0.0104 | -0.7169 | 2.3375 | |
| HBL-100 | Unknown | Unknown | Etoposide | TOP2 | TOP | 333 | uM | 7429.074 | 0.0073 | -0.7559 | 2.3375 | |
| HCC1143 | TNBC | Basal A | Etoposide | TOP2 | TOP | 0.000853 | uM | 7430.074 | 1.0554 | 1.0647 | 1.6943 |