Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC1569 | HER2amp | Basal A | NU6102 | CDK1/2 | CDK | 0.533 | uM | 12523.147 | 1.0673 | 1.1466 | 0.9214 | |
| HCC1569 | HER2amp | Basal A | NU6102 | CDK1/2 | CDK | 2.67 | uM | 12523.147 | 1.0716 | 1.1558 | 0.9214 | |
| HCC1569 | HER2amp | Basal A | NU6102 | CDK1/2 | CDK | 13.3 | uM | 12523.147 | 0.9449 | 0.8807 | 0.9214 | |
| HCC1569 | HER2amp | Basal A | NU6102 | CDK1/2 | CDK | 66.7 | uM | 12523.147 | 0.4125 | -0.2350 | 0.9214 | |
| HCC1806 | TNBC | Basal A | NU6102 | CDK1/2 | CDK | 0.000171 | uM | 12239.147 | 0.9956 | 0.9956 | 2.0027 | |
| HCC1806 | TNBC | Basal A | NU6102 | CDK1/2 | CDK | 0.000853 | uM | 12239.147 | 0.9846 | 0.9845 | 2.0027 | |
| HCC1806 | TNBC | Basal A | NU6102 | CDK1/2 | CDK | 0.00427 | uM | 12239.147 | 1.0104 | 1.0103 | 2.0027 | |
| HCC1806 | TNBC | Basal A | NU6102 | CDK1/2 | CDK | 0.0213 | uM | 12239.147 | 0.9984 | 0.9984 | 2.0027 | |
| HCC1806 | TNBC | Basal A | NU6102 | CDK1/2 | CDK | 0.107 | uM | 12239.147 | 0.9593 | 0.9589 | 2.0027 | |
| HCC1806 | TNBC | Basal A | NU6102 | CDK1/2 | CDK | 0.533 | uM | 12239.147 | 1.0102 | 1.0102 | 2.0027 | |
| HCC1806 | TNBC | Basal A | NU6102 | CDK1/2 | CDK | 2.67 | uM | 12239.147 | 1.0442 | 1.0437 | 2.0027 | |
| HCC1806 | TNBC | Basal A | NU6102 | CDK1/2 | CDK | 13.3 | uM | 12239.147 | 0.8391 | 0.8323 | 2.0027 | |
| HCC1806 | TNBC | Basal A | NU6102 | CDK1/2 | CDK | 66.7 | uM | 12239.147 | 0.0376 | -0.6115 | 2.0027 | |
| HCC1937 | TNBC | Basal A | NU6102 | CDK1/2 | CDK | 0.000171 | uM | 11849.147 | 0.9854 | 0.9782 | 1.3461 | |
| HCC1937 | TNBC | Basal A | NU6102 | CDK1/2 | CDK | 0.000853 | uM | 11849.147 | 1.0189 | 1.0279 | 1.3461 | |
| HCC1937 | TNBC | Basal A | NU6102 | CDK1/2 | CDK | 0.00427 | uM | 11849.147 | 0.9801 | 0.9704 | 1.3461 | |
| HCC1937 | TNBC | Basal A | NU6102 | CDK1/2 | CDK | 0.0213 | uM | 11849.147 | 1.0078 | 1.0115 | 1.3461 | |
| HCC1937 | TNBC | Basal A | NU6102 | CDK1/2 | CDK | 0.107 | uM | 11849.147 | 1.0687 | 1.1012 | 1.3461 | |
| HCC1937 | TNBC | Basal A | NU6102 | CDK1/2 | CDK | 0.533 | uM | 11849.147 | 0.9666 | 0.9502 | 1.3461 | |
| HCC1937 | TNBC | Basal A | NU6102 | CDK1/2 | CDK | 2.67 | uM | 11849.147 | 0.9770 | 0.9657 | 1.3461 | |
| HCC1937 | TNBC | Basal A | NU6102 | CDK1/2 | CDK | 13.3 | uM | 11849.147 | 1.0312 | 1.0461 | 1.3461 | |
| HCC1937 | TNBC | Basal A | NU6102 | CDK1/2 | CDK | 66.7 | uM | 11849.147 | 0.2356 | -0.3167 | 1.3461 | |
| HCC1954 | HER2amp | Basal A | NU6102 | CDK1/2 | CDK | 0.000171 | uM | 11055.147 | 0.9636 | 0.9565 | 1.6841 | |
| HCC1954 | HER2amp | Basal A | NU6102 | CDK1/2 | CDK | 0.000853 | uM | 11055.147 | 0.9432 | 0.9318 | 1.6841 | |
| HCC1954 | HER2amp | Basal A | NU6102 | CDK1/2 | CDK | 0.00427 | uM | 11055.147 | 1.0003 | 1.0004 | 1.6841 |