Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC38 | TNBC | Basal B | Omipalisib | PI3K | PI3K | 0.0107 | uM | 10418.087 | 0.8296 | 0.7001 | 1.1498 | |
| HCC38 | TNBC | Basal B | Omipalisib | PI3K | PI3K | 0.0533 | uM | 10418.087 | 0.6098 | 0.3008 | 1.1498 | |
| HCC38 | TNBC | Basal B | Omipalisib | PI3K | PI3K | 0.267 | uM | 10418.087 | 0.2750 | -0.3493 | 1.1498 | |
| HCC38 | TNBC | Basal B | Omipalisib | PI3K | PI3K | 1.33 | uM | 10418.087 | 0.1592 | -0.5955 | 1.1498 | |
| HCC38 | TNBC | Basal B | Omipalisib | PI3K | PI3K | 6.67 | uM | 10418.087 | 0.1257 | -0.6705 | 1.1498 | |
| HCC38 | TNBC | Basal B | Omipalisib | PI3K | PI3K | 33.3 | uM | 10418.087 | 0.0600 | -0.8268 | 1.1498 | |
| HCC38 | TNBC | Basal B | Omipalisib | PI3K | PI3K | 0.0000853 | uM | 10578.087 | 1.1202 | 1.1798 | 1.3188 | |
| HCC38 | TNBC | Basal B | Omipalisib | PI3K | PI3K | 0.000427 | uM | 10578.087 | 1.0157 | 1.0238 | 1.3188 | |
| HCC38 | TNBC | Basal B | Omipalisib | PI3K | PI3K | 0.00213 | uM | 10578.087 | 0.9778 | 0.9662 | 1.3188 | |
| HCC38 | TNBC | Basal B | Omipalisib | PI3K | PI3K | 0.0107 | uM | 10578.087 | 0.8946 | 0.8380 | 1.3188 | |
| HCC38 | TNBC | Basal B | Omipalisib | PI3K | PI3K | 0.0533 | uM | 10578.087 | 0.7255 | 0.5680 | 1.3188 | |
| HCC38 | TNBC | Basal B | Omipalisib | PI3K | PI3K | 0.267 | uM | 10578.087 | 0.2749 | -0.2487 | 1.3188 | |
| HCC38 | TNBC | Basal B | Omipalisib | PI3K | PI3K | 1.33 | uM | 10578.087 | 0.1351 | -0.5617 | 1.3188 | |
| HCC38 | TNBC | Basal B | Omipalisib | PI3K | PI3K | 6.67 | uM | 10578.087 | 0.0675 | -0.7411 | 1.3188 | |
| HCC38 | TNBC | Basal B | Omipalisib | PI3K | PI3K | 33.3 | uM | 10578.087 | 0.0245 | -0.8799 | 1.3188 | |
| HCC70 | TNBC | Basal A | Omipalisib | PI3K | PI3K | 0.0000853 | uM | 7470.086 | 0.9820 | 0.9627 | 0.9669 | |
| HCC70 | TNBC | Basal A | Omipalisib | PI3K | PI3K | 0.000427 | uM | 7470.086 | 0.9449 | 0.8862 | 0.9669 | |
| HCC70 | TNBC | Basal A | Omipalisib | PI3K | PI3K | 0.00213 | uM | 7470.086 | 0.8750 | 0.7420 | 0.9669 | |
| HCC70 | TNBC | Basal A | Omipalisib | PI3K | PI3K | 0.0107 | uM | 7470.086 | 0.7457 | 0.4765 | 0.9669 | |
| HCC70 | TNBC | Basal A | Omipalisib | PI3K | PI3K | 0.0533 | uM | 7470.086 | 0.3428 | -0.3391 | 0.9669 | |
| HCC70 | TNBC | Basal A | Omipalisib | PI3K | PI3K | 0.267 | uM | 7470.086 | 0.1662 | -0.6875 | 0.9669 | |
| HCC70 | TNBC | Basal A | Omipalisib | PI3K | PI3K | 1.33 | uM | 7470.086 | 0.1053 | -0.8050 | 0.9669 | |
| HCC70 | TNBC | Basal A | Omipalisib | PI3K | PI3K | 6.67 | uM | 7470.086 | 0.0330 | -0.9413 | 0.9669 | |
| HCC70 | TNBC | Basal A | Omipalisib | PI3K | PI3K | 33.3 | uM | 7470.086 | 0.0410 | -0.9265 | 0.9669 | |
| Hs 578T | TNBC | Basal B | Omipalisib | PI3K | PI3K | 0.0000853 | uM | 7471.087 | 0.9334 | 0.7795 | 0.5895 |