Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC1428 | HR+ | Luminal | NU6102 | CDK1/2 | CDK | 13.3 | uM | 10693.147 | 0.7721 | 0.4945 | 0.8879 | |
| HCC1428 | HR+ | Luminal | NU6102 | CDK1/2 | CDK | 66.7 | uM | 10693.147 | 0.0955 | -0.8580 | 0.8879 | |
| HCC1428 | HR+ | Luminal | NU6102 | CDK1/2 | CDK | 0.000171 | uM | 11936.147 | 0.9048 | 0.7936 | 0.9187 | |
| HCC1428 | HR+ | Luminal | NU6102 | CDK1/2 | CDK | 0.000853 | uM | 11936.147 | 0.8676 | 0.7135 | 0.9187 | |
| HCC1428 | HR+ | Luminal | NU6102 | CDK1/2 | CDK | 0.00427 | uM | 11936.147 | 0.9406 | 0.8710 | 0.9187 | |
| HCC1428 | HR+ | Luminal | NU6102 | CDK1/2 | CDK | 0.0213 | uM | 11936.147 | 0.9505 | 0.8925 | 0.9187 | |
| HCC1428 | HR+ | Luminal | NU6102 | CDK1/2 | CDK | 0.107 | uM | 11936.147 | 0.9506 | 0.8928 | 0.9187 | |
| HCC1428 | HR+ | Luminal | NU6102 | CDK1/2 | CDK | 0.533 | uM | 11936.147 | 0.9250 | 0.8372 | 0.9187 | |
| HCC1428 | HR+ | Luminal | NU6102 | CDK1/2 | CDK | 2.67 | uM | 11936.147 | 0.9388 | 0.8672 | 0.9187 | |
| HCC1428 | HR+ | Luminal | NU6102 | CDK1/2 | CDK | 13.3 | uM | 11936.147 | 0.7832 | 0.5330 | 0.9187 | |
| HCC1428 | HR+ | Luminal | NU6102 | CDK1/2 | CDK | 66.7 | uM | 11936.147 | 0.1546 | -0.7379 | 0.9187 | |
| HCC1569 | HER2amp | Basal A | NU6102 | CDK1/2 | CDK | 0.000171 | uM | 10872.147 | 0.9026 | 0.8778 | 1.6255 | |
| HCC1569 | HER2amp | Basal A | NU6102 | CDK1/2 | CDK | 0.000853 | uM | 10872.147 | 0.9405 | 0.9259 | 1.6255 | |
| HCC1569 | HER2amp | Basal A | NU6102 | CDK1/2 | CDK | 0.00427 | uM | 10872.147 | 0.9065 | 0.8828 | 1.6255 | |
| HCC1569 | HER2amp | Basal A | NU6102 | CDK1/2 | CDK | 0.0213 | uM | 10872.147 | 0.9181 | 0.8975 | 1.6255 | |
| HCC1569 | HER2amp | Basal A | NU6102 | CDK1/2 | CDK | 0.107 | uM | 10872.147 | 0.9398 | 0.9250 | 1.6255 | |
| HCC1569 | HER2amp | Basal A | NU6102 | CDK1/2 | CDK | 0.533 | uM | 10872.147 | 0.9318 | 0.9149 | 1.6255 | |
| HCC1569 | HER2amp | Basal A | NU6102 | CDK1/2 | CDK | 2.67 | uM | 10872.147 | 0.9446 | 0.9311 | 1.6255 | |
| HCC1569 | HER2amp | Basal A | NU6102 | CDK1/2 | CDK | 13.3 | uM | 10872.147 | 0.8178 | 0.7673 | 1.6255 | |
| HCC1569 | HER2amp | Basal A | NU6102 | CDK1/2 | CDK | 66.7 | uM | 10872.147 | 0.1737 | -0.3187 | 1.6255 | |
| HCC1569 | HER2amp | Basal A | NU6102 | CDK1/2 | CDK | 0.000171 | uM | 12523.147 | 1.0057 | 1.0124 | 0.9214 | |
| HCC1569 | HER2amp | Basal A | NU6102 | CDK1/2 | CDK | 0.000853 | uM | 12523.147 | 1.0440 | 1.0958 | 0.9214 | |
| HCC1569 | HER2amp | Basal A | NU6102 | CDK1/2 | CDK | 0.00427 | uM | 12523.147 | 0.9924 | 0.9836 | 0.9214 | |
| HCC1569 | HER2amp | Basal A | NU6102 | CDK1/2 | CDK | 0.0213 | uM | 12523.147 | 1.0427 | 1.0929 | 0.9214 | |
| HCC1569 | HER2amp | Basal A | NU6102 | CDK1/2 | CDK | 0.107 | uM | 12523.147 | 0.9889 | 0.9758 | 0.9214 |