Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC3153 | TNBC | Basal A | Omipalisib | PI3K | PI3K | 0.267 | uM | 7466.087 | 0.5391 | 0.0163 | 0.9127 | |
| HCC3153 | TNBC | Basal A | Omipalisib | PI3K | PI3K | 1.33 | uM | 7466.087 | 0.3784 | -0.3103 | 0.9127 | |
| HCC3153 | TNBC | Basal A | Omipalisib | PI3K | PI3K | 6.67 | uM | 7466.087 | 0.3296 | -0.4071 | 0.9127 | |
| HCC3153 | TNBC | Basal A | Omipalisib | PI3K | PI3K | 33.3 | uM | 7466.087 | 0.2710 | -0.5216 | 0.9127 | |
| HCC3153 | TNBC | Basal A | Omipalisib | PI3K | PI3K | 0.0000853 | uM | 10577.087 | 1.0098 | 1.0212 | 0.9288 | |
| HCC3153 | TNBC | Basal A | Omipalisib | PI3K | PI3K | 0.000427 | uM | 10577.087 | 0.9267 | 0.8425 | 0.9288 | |
| HCC3153 | TNBC | Basal A | Omipalisib | PI3K | PI3K | 0.00213 | uM | 10577.087 | 0.8978 | 0.7809 | 0.9288 | |
| HCC3153 | TNBC | Basal A | Omipalisib | PI3K | PI3K | 0.0107 | uM | 10577.087 | 0.8566 | 0.6930 | 0.9288 | |
| HCC3153 | TNBC | Basal A | Omipalisib | PI3K | PI3K | 0.0533 | uM | 10577.087 | 0.7475 | 0.4619 | 0.9288 | |
| HCC3153 | TNBC | Basal A | Omipalisib | PI3K | PI3K | 0.267 | uM | 10577.087 | 0.4827 | -0.0870 | 0.9288 | |
| HCC3153 | TNBC | Basal A | Omipalisib | PI3K | PI3K | 1.33 | uM | 10577.087 | 0.3715 | -0.3113 | 0.9288 | |
| HCC3153 | TNBC | Basal A | Omipalisib | PI3K | PI3K | 6.67 | uM | 10577.087 | 0.2529 | -0.5448 | 0.9288 | |
| HCC3153 | TNBC | Basal A | Omipalisib | PI3K | PI3K | 33.3 | uM | 10577.087 | 0.1860 | -0.6730 | 0.9288 | |
| HCC38 | TNBC | Basal B | Omipalisib | PI3K | PI3K | 0.0000853 | uM | 7468.086 | 1.0412 | 1.0633 | 1.2962 | |
| HCC38 | TNBC | Basal B | Omipalisib | PI3K | PI3K | 0.000427 | uM | 7468.086 | 0.9850 | 0.9769 | 1.2962 | |
| HCC38 | TNBC | Basal B | Omipalisib | PI3K | PI3K | 0.00213 | uM | 7468.086 | 0.9508 | 0.9236 | 1.2962 | |
| HCC38 | TNBC | Basal B | Omipalisib | PI3K | PI3K | 0.0107 | uM | 7468.086 | 0.8289 | 0.7305 | 1.2962 | |
| HCC38 | TNBC | Basal B | Omipalisib | PI3K | PI3K | 0.0533 | uM | 7468.086 | 0.5469 | 0.2555 | 1.2962 | |
| HCC38 | TNBC | Basal B | Omipalisib | PI3K | PI3K | 0.267 | uM | 7468.086 | 0.2197 | -0.3788 | 1.2962 | |
| HCC38 | TNBC | Basal B | Omipalisib | PI3K | PI3K | 1.33 | uM | 7468.086 | 0.1122 | -0.6300 | 1.2962 | |
| HCC38 | TNBC | Basal B | Omipalisib | PI3K | PI3K | 6.67 | uM | 7468.086 | 0.0718 | -0.7378 | 1.2962 | |
| HCC38 | TNBC | Basal B | Omipalisib | PI3K | PI3K | 33.3 | uM | 7468.086 | 0.0533 | -0.7918 | 1.2962 | |
| HCC38 | TNBC | Basal B | Omipalisib | PI3K | PI3K | 0.0000853 | uM | 10418.087 | 0.9753 | 0.9570 | 1.1498 | |
| HCC38 | TNBC | Basal B | Omipalisib | PI3K | PI3K | 0.000427 | uM | 10418.087 | 0.8682 | 0.7687 | 1.1498 | |
| HCC38 | TNBC | Basal B | Omipalisib | PI3K | PI3K | 0.00213 | uM | 10418.087 | 0.8958 | 0.8176 | 1.1498 |