Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| UACC-812 | HER2amp | Luminal | NSC 663284 | CDC25 | CDC | 33.3 | uM | 10580.14 | 0.0107 | -0.9893 | 0.8679 | |
| UACC-812 | HER2amp | Luminal | NSC 663284 | CDC25 | CDC | 167 | uM | 10580.14 | 0.0085 | -0.9917 | 0.8679 | |
| UACC-812 | HER2amp | Luminal | NSC 663284 | CDC25 | CDC | 0.000427 | uM | 10754.152 | 1.0352 | 1.0660 | 1.0670 | |
| UACC-812 | HER2amp | Luminal | NSC 663284 | CDC25 | CDC | 0.00213 | uM | 10754.152 | 0.9917 | 0.9845 | 1.0670 | |
| UACC-812 | HER2amp | Luminal | NSC 663284 | CDC25 | CDC | 0.0107 | uM | 10754.152 | 0.9363 | 0.8803 | 1.0670 | |
| UACC-812 | HER2amp | Luminal | NSC 663284 | CDC25 | CDC | 0.0533 | uM | 10754.152 | 0.9383 | 0.8842 | 1.0670 | |
| UACC-812 | HER2amp | Luminal | NSC 663284 | CDC25 | CDC | 0.267 | uM | 10754.152 | 0.9762 | 0.9553 | 1.0670 | |
| UACC-812 | HER2amp | Luminal | NSC 663284 | CDC25 | CDC | 1.33 | uM | 10754.152 | 0.8456 | 0.7090 | 1.0670 | |
| UACC-812 | HER2amp | Luminal | NSC 663284 | CDC25 | CDC | 6.67 | uM | 10754.152 | 0.3822 | -0.1880 | 1.0670 | |
| UACC-812 | HER2amp | Luminal | NSC 663284 | CDC25 | CDC | 33.3 | uM | 10754.152 | 0.0127 | -0.9666 | 1.0670 | |
| UACC-812 | HER2amp | Luminal | NSC 663284 | CDC25 | CDC | 167 | uM | 10754.152 | 0.0143 | -0.9628 | 1.0670 | |
| UACC-812 | HER2amp | Luminal | NSC 663284 | CDC25 | CDC | 0.000427 | uM | 11938.159 | 1.0586 | 1.2889 | 0.4219 | |
| UACC-812 | HER2amp | Luminal | NSC 663284 | CDC25 | CDC | 0.00213 | uM | 11938.159 | 1.0461 | 1.2256 | 0.4219 | |
| UACC-812 | HER2amp | Luminal | NSC 663284 | CDC25 | CDC | 0.0107 | uM | 11938.159 | 1.0185 | 1.0888 | 0.4219 | |
| UACC-812 | HER2amp | Luminal | NSC 663284 | CDC25 | CDC | 0.0533 | uM | 11938.159 | 1.0028 | 1.0133 | 0.4219 | |
| UACC-812 | HER2amp | Luminal | NSC 663284 | CDC25 | CDC | 0.267 | uM | 11938.159 | 1.0257 | 1.1240 | 0.4219 | |
| UACC-812 | HER2amp | Luminal | NSC 663284 | CDC25 | CDC | 1.33 | uM | 11938.159 | 1.0275 | 1.1329 | 0.4219 | |
| UACC-812 | HER2amp | Luminal | NSC 663284 | CDC25 | CDC | 6.67 | uM | 11938.159 | 0.4630 | -0.6777 | 0.4219 | |
| UACC-812 | HER2amp | Luminal | NSC 663284 | CDC25 | CDC | 33.3 | uM | 11938.159 | 0.0174 | -0.9999 | 0.4219 | |
| UACC-812 | HER2amp | Luminal | NSC 663284 | CDC25 | CDC | 167 | uM | 11938.159 | 0.0161 | -0.9999 | 0.4219 | |
| ZR-75-1 | HR+ | Luminal | NSC 663284 | CDC25 | CDC | 0.000427 | uM | 11660.152 | 0.9817 | 0.9632 | 0.9953 | |
| ZR-75-1 | HR+ | Luminal | NSC 663284 | CDC25 | CDC | 0.00213 | uM | 11660.152 | 0.9353 | 0.8700 | 0.9953 | |
| ZR-75-1 | HR+ | Luminal | NSC 663284 | CDC25 | CDC | 0.0107 | uM | 11660.152 | 0.9739 | 0.9475 | 0.9953 | |
| ZR-75-1 | HR+ | Luminal | NSC 663284 | CDC25 | CDC | 0.0533 | uM | 11660.152 | 0.9431 | 0.8857 | 0.9953 | |
| ZR-75-1 | HR+ | Luminal | NSC 663284 | CDC25 | CDC | 0.267 | uM | 11660.152 | 0.9747 | 0.9491 | 0.9953 |