Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC1954 | HER2amp | Basal A | NU6102 | CDK1/2 | CDK | 0.0213 | uM | 11055.147 | 1.0245 | 1.0290 | 1.6841 | |
| HCC1954 | HER2amp | Basal A | NU6102 | CDK1/2 | CDK | 0.107 | uM | 11055.147 | 1.0234 | 1.0277 | 1.6841 | |
| HCC1954 | HER2amp | Basal A | NU6102 | CDK1/2 | CDK | 0.533 | uM | 11055.147 | 0.9815 | 0.9779 | 1.6841 | |
| HCC1954 | HER2amp | Basal A | NU6102 | CDK1/2 | CDK | 2.67 | uM | 11055.147 | 0.9722 | 0.9668 | 1.6841 | |
| HCC1954 | HER2amp | Basal A | NU6102 | CDK1/2 | CDK | 13.3 | uM | 11055.147 | 0.9457 | 0.9348 | 1.6841 | |
| HCC1954 | HER2amp | Basal A | NU6102 | CDK1/2 | CDK | 66.7 | uM | 11055.147 | 0.4421 | 0.2318 | 1.6841 | |
| HCC2185 | TNBC | Luminal | NU6102 | CDK1/2 | CDK | 0.000171 | uM | 10996.147 | 0.9519 | 0.8486 | 0.6261 | |
| HCC2185 | TNBC | Luminal | NU6102 | CDK1/2 | CDK | 0.000853 | uM | 10996.147 | 1.0182 | 1.0584 | 0.6261 | |
| HCC2185 | TNBC | Luminal | NU6102 | CDK1/2 | CDK | 0.00427 | uM | 10996.147 | 0.9981 | 0.9940 | 0.6261 | |
| HCC2185 | TNBC | Luminal | NU6102 | CDK1/2 | CDK | 0.0213 | uM | 10996.147 | 0.9865 | 0.9570 | 0.6261 | |
| HCC2185 | TNBC | Luminal | NU6102 | CDK1/2 | CDK | 0.107 | uM | 10996.147 | 1.0411 | 1.1330 | 0.6261 | |
| HCC2185 | TNBC | Luminal | NU6102 | CDK1/2 | CDK | 0.533 | uM | 10996.147 | 0.9666 | 0.8942 | 0.6261 | |
| HCC2185 | TNBC | Luminal | NU6102 | CDK1/2 | CDK | 2.67 | uM | 10996.147 | 1.0352 | 1.1135 | 0.6261 | |
| HCC2185 | TNBC | Luminal | NU6102 | CDK1/2 | CDK | 13.3 | uM | 10996.147 | 0.9021 | 0.6964 | 0.6261 | |
| HCC2185 | TNBC | Luminal | NU6102 | CDK1/2 | CDK | 66.7 | uM | 10996.147 | 0.1703 | -0.8817 | 0.6261 | |
| HCC2185 | TNBC | Luminal | NU6102 | CDK1/2 | CDK | 0.000171 | uM | 12192.147 | 0.9742 | 0.9093 | 0.5645 | |
| HCC2185 | TNBC | Luminal | NU6102 | CDK1/2 | CDK | 0.000853 | uM | 12192.147 | 0.9473 | 0.8172 | 0.5645 | |
| HCC2185 | TNBC | Luminal | NU6102 | CDK1/2 | CDK | 0.00427 | uM | 12192.147 | 0.9456 | 0.8115 | 0.5645 | |
| HCC2185 | TNBC | Luminal | NU6102 | CDK1/2 | CDK | 0.0213 | uM | 12192.147 | 0.9735 | 0.9072 | 0.5645 | |
| HCC2185 | TNBC | Luminal | NU6102 | CDK1/2 | CDK | 0.107 | uM | 12192.147 | 1.0268 | 1.0959 | 0.5645 | |
| HCC2185 | TNBC | Luminal | NU6102 | CDK1/2 | CDK | 0.533 | uM | 12192.147 | 0.9808 | 0.9326 | 0.5645 | |
| HCC2185 | TNBC | Luminal | NU6102 | CDK1/2 | CDK | 2.67 | uM | 12192.147 | 1.0283 | 1.1014 | 0.5645 | |
| HCC2185 | TNBC | Luminal | NU6102 | CDK1/2 | CDK | 13.3 | uM | 12192.147 | 0.8613 | 0.5352 | 0.5645 | |
| HCC2185 | TNBC | Luminal | NU6102 | CDK1/2 | CDK | 66.7 | uM | 12192.147 | 0.4777 | -0.4596 | 0.5645 | |
| HCC3153 | TNBC | Basal A | NU6102 | CDK1/2 | CDK | 0.000171 | uM | 10937.147 | 0.9497 | 0.9197 | 1.2614 |