Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Hs 578T | TNBC | Basal B | Omipalisib | PI3K | PI3K | 0.000427 | uM | 7471.087 | 0.7682 | 0.2787 | 0.5895 | |
| Hs 578T | TNBC | Basal B | Omipalisib | PI3K | PI3K | 0.00213 | uM | 7471.087 | 0.9142 | 0.7178 | 0.5895 | |
| Hs 578T | TNBC | Basal B | Omipalisib | PI3K | PI3K | 0.0107 | uM | 7471.087 | 0.6212 | -0.1083 | 0.5895 | |
| Hs 578T | TNBC | Basal B | Omipalisib | PI3K | PI3K | 0.0533 | uM | 7471.087 | 0.6477 | -0.0426 | 0.5895 | |
| Hs 578T | TNBC | Basal B | Omipalisib | PI3K | PI3K | 0.267 | uM | 7471.087 | 0.4720 | -0.4404 | 0.5895 | |
| Hs 578T | TNBC | Basal B | Omipalisib | PI3K | PI3K | 1.33 | uM | 7471.087 | 0.2647 | -0.7902 | 0.5895 | |
| Hs 578T | TNBC | Basal B | Omipalisib | PI3K | PI3K | 6.67 | uM | 7471.087 | 0.1755 | -0.8955 | 0.5895 | |
| Hs 578T | TNBC | Basal B | Omipalisib | PI3K | PI3K | 33.3 | uM | 7471.087 | 0.1255 | -0.9408 | 0.5895 | |
| Hs 578T | TNBC | Basal B | Omipalisib | PI3K | PI3K | 0.0000853 | uM | 7472.087 | 0.9732 | 0.9773 | 2.3804 | |
| Hs 578T | TNBC | Basal B | Omipalisib | PI3K | PI3K | 0.000427 | uM | 7472.087 | 0.8991 | 0.9126 | 2.3804 | |
| Hs 578T | TNBC | Basal B | Omipalisib | PI3K | PI3K | 0.00213 | uM | 7472.087 | 0.9865 | 0.9886 | 2.3804 | |
| Hs 578T | TNBC | Basal B | Omipalisib | PI3K | PI3K | 0.0107 | uM | 7472.087 | 1.3961 | 1.3010 | 2.3804 | |
| Hs 578T | TNBC | Basal B | Omipalisib | PI3K | PI3K | 0.0533 | uM | 7472.087 | 1.3621 | 1.2773 | 2.3804 | |
| Hs 578T | TNBC | Basal B | Omipalisib | PI3K | PI3K | 0.267 | uM | 7472.087 | 0.7198 | 0.7420 | 2.3804 | |
| Hs 578T | TNBC | Basal B | Omipalisib | PI3K | PI3K | 1.33 | uM | 7472.087 | 0.5331 | 0.5355 | 2.3804 | |
| Hs 578T | TNBC | Basal B | Omipalisib | PI3K | PI3K | 6.67 | uM | 7472.087 | 0.4856 | 0.4765 | 2.3804 | |
| Hs 578T | TNBC | Basal B | Omipalisib | PI3K | PI3K | 33.3 | uM | 7472.087 | 0.4682 | 0.4540 | 2.3804 | |
| Hs 578T | TNBC | Basal B | Omipalisib | PI3K | PI3K | 0.0000853 | uM | 10379.087 | 1.0416 | 1.0337 | 2.4420 | |
| Hs 578T | TNBC | Basal B | Omipalisib | PI3K | PI3K | 0.000427 | uM | 10379.087 | 0.9567 | 0.9641 | 2.4420 | |
| Hs 578T | TNBC | Basal B | Omipalisib | PI3K | PI3K | 0.00213 | uM | 10379.087 | 0.9074 | 0.9220 | 2.4420 | |
| Hs 578T | TNBC | Basal B | Omipalisib | PI3K | PI3K | 0.0107 | uM | 10379.087 | 0.8610 | 0.8811 | 2.4420 | |
| Hs 578T | TNBC | Basal B | Omipalisib | PI3K | PI3K | 0.0533 | uM | 10379.087 | 0.6552 | 0.6820 | 2.4420 | |
| Hs 578T | TNBC | Basal B | Omipalisib | PI3K | PI3K | 0.267 | uM | 10379.087 | 0.3563 | 0.3106 | 2.4420 | |
| Hs 578T | TNBC | Basal B | Omipalisib | PI3K | PI3K | 1.33 | uM | 10379.087 | 0.2424 | 0.1195 | 2.4420 | |
| Hs 578T | TNBC | Basal B | Omipalisib | PI3K | PI3K | 6.67 | uM | 10379.087 | 0.2116 | 0.0587 | 2.4420 |