Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC1419 | HER2amp | Luminal | JNK-IN-5A | JNK | JNK | 8 | uM | 12001.168 | 0.8330 | 0.3811 | 0.4934 | |
| HCC1419 | HER2amp | Luminal | JNK-IN-5A | JNK | JNK | 40 | uM | 12001.168 | 0.8365 | 0.3928 | 0.4934 | |
| HCC1419 | HER2amp | Luminal | JNK-IN-5A | JNK | JNK | 200 | uM | 12001.168 | 0.9438 | 0.7789 | 0.4934 | |
| HCC1428 | HR+ | Luminal | JNK-IN-5A | JNK | JNK | 0.000341 | uM | 10693.144 | 1.0218 | 1.0509 | 0.8585 | |
| HCC1428 | HR+ | Luminal | JNK-IN-5A | JNK | JNK | 0.00171 | uM | 10693.144 | 1.0013 | 1.0030 | 0.8585 | |
| HCC1428 | HR+ | Luminal | JNK-IN-5A | JNK | JNK | 0.00853 | uM | 10693.144 | 0.9958 | 0.9902 | 0.8585 | |
| HCC1428 | HR+ | Luminal | JNK-IN-5A | JNK | JNK | 0.0427 | uM | 10693.144 | 0.9977 | 0.9947 | 0.8585 | |
| HCC1428 | HR+ | Luminal | JNK-IN-5A | JNK | JNK | 0.213 | uM | 10693.144 | 0.9925 | 0.9826 | 0.8585 | |
| HCC1428 | HR+ | Luminal | JNK-IN-5A | JNK | JNK | 1.07 | uM | 10693.144 | 0.7238 | 0.3725 | 0.8585 | |
| HCC1428 | HR+ | Luminal | JNK-IN-5A | JNK | JNK | 5.33 | uM | 10693.144 | 0.7325 | 0.3916 | 0.8585 | |
| HCC1428 | HR+ | Luminal | JNK-IN-5A | JNK | JNK | 26.7 | uM | 10693.144 | 0.8188 | 0.5845 | 0.8585 | |
| HCC1428 | HR+ | Luminal | JNK-IN-5A | JNK | JNK | 133 | uM | 10693.144 | 0.8001 | 0.5424 | 0.8585 | |
| HCC1428 | HR+ | Luminal | JNK-IN-5A | JNK | JNK | 0.000341 | uM | 11936.144 | 0.9907 | 0.9790 | 0.8864 | |
| HCC1428 | HR+ | Luminal | JNK-IN-5A | JNK | JNK | 0.00171 | uM | 11936.144 | 0.9164 | 0.8124 | 0.8864 | |
| HCC1428 | HR+ | Luminal | JNK-IN-5A | JNK | JNK | 0.00853 | uM | 11936.144 | 1.0183 | 1.0414 | 0.8864 | |
| HCC1428 | HR+ | Luminal | JNK-IN-5A | JNK | JNK | 0.0427 | uM | 11936.144 | 0.9792 | 0.9532 | 0.8864 | |
| HCC1428 | HR+ | Luminal | JNK-IN-5A | JNK | JNK | 0.213 | uM | 11936.144 | 0.9907 | 0.9790 | 0.8864 | |
| HCC1428 | HR+ | Luminal | JNK-IN-5A | JNK | JNK | 1.07 | uM | 11936.144 | 0.9968 | 0.9929 | 0.8864 | |
| HCC1428 | HR+ | Luminal | JNK-IN-5A | JNK | JNK | 5.33 | uM | 11936.144 | 0.6489 | 0.2279 | 0.8864 | |
| HCC1428 | HR+ | Luminal | JNK-IN-5A | JNK | JNK | 26.7 | uM | 11936.144 | 0.8366 | 0.6354 | 0.8864 | |
| HCC1428 | HR+ | Luminal | JNK-IN-5A | JNK | JNK | 133 | uM | 11936.144 | 0.6560 | 0.2430 | 0.8864 | |
| HCC1569 | HER2amp | Basal A | JNK-IN-5A | JNK | JNK | 0.000341 | uM | 10872.144 | 1.0311 | 1.0401 | 1.5447 | |
| HCC1569 | HER2amp | Basal A | JNK-IN-5A | JNK | JNK | 0.00171 | uM | 10872.144 | 1.0545 | 1.0700 | 1.5447 | |
| HCC1569 | HER2amp | Basal A | JNK-IN-5A | JNK | JNK | 0.00853 | uM | 10872.144 | 1.0196 | 1.0253 | 1.5447 | |
| HCC1569 | HER2amp | Basal A | JNK-IN-5A | JNK | JNK | 0.0427 | uM | 10872.144 | 1.0872 | 1.1112 | 1.5447 |