Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC1569 | HER2amp | Basal A | JNK-IN-5A | JNK | JNK | 0.213 | uM | 10872.144 | 1.0336 | 1.0433 | 1.5447 | |
| HCC1569 | HER2amp | Basal A | JNK-IN-5A | JNK | JNK | 1.07 | uM | 10872.144 | 0.9532 | 0.9388 | 1.5447 | |
| HCC1569 | HER2amp | Basal A | JNK-IN-5A | JNK | JNK | 5.33 | uM | 10872.144 | 0.6251 | 0.4755 | 1.5447 | |
| HCC1569 | HER2amp | Basal A | JNK-IN-5A | JNK | JNK | 26.7 | uM | 10872.144 | 0.8142 | 0.7508 | 1.5447 | |
| HCC1569 | HER2amp | Basal A | JNK-IN-5A | JNK | JNK | 133 | uM | 10872.144 | 0.6984 | 0.5853 | 1.5447 | |
| HCC1569 | HER2amp | Basal A | JNK-IN-5A | JNK | JNK | 0.000512 | uM | 12523.168 | 0.9912 | 0.9806 | 0.9035 | |
| HCC1569 | HER2amp | Basal A | JNK-IN-5A | JNK | JNK | 0.00256 | uM | 12523.168 | 0.9926 | 0.9835 | 0.9035 | |
| HCC1569 | HER2amp | Basal A | JNK-IN-5A | JNK | JNK | 0.0128 | uM | 12523.168 | 1.0204 | 1.0453 | 0.9035 | |
| HCC1569 | HER2amp | Basal A | JNK-IN-5A | JNK | JNK | 0.064 | uM | 12523.168 | 0.9847 | 0.9661 | 0.9035 | |
| HCC1569 | HER2amp | Basal A | JNK-IN-5A | JNK | JNK | 0.32 | uM | 12523.168 | 1.0181 | 1.0402 | 0.9035 | |
| HCC1569 | HER2amp | Basal A | JNK-IN-5A | JNK | JNK | 1.6 | uM | 12523.168 | 1.0188 | 1.0416 | 0.9035 | |
| HCC1569 | HER2amp | Basal A | JNK-IN-5A | JNK | JNK | 8 | uM | 12523.168 | 0.9715 | 0.9370 | 0.9035 | |
| HCC1569 | HER2amp | Basal A | JNK-IN-5A | JNK | JNK | 40 | uM | 12523.168 | 0.9703 | 0.9344 | 0.9035 | |
| HCC1569 | HER2amp | Basal A | JNK-IN-5A | JNK | JNK | 200 | uM | 12523.168 | 0.7457 | 0.4453 | 0.9035 | |
| HCC1806 | TNBC | Basal A | JNK-IN-5A | JNK | JNK | 0.000341 | uM | 12239.144 | 0.9745 | 0.9762 | 2.1598 | |
| HCC1806 | TNBC | Basal A | JNK-IN-5A | JNK | JNK | 0.00171 | uM | 12239.144 | 1.0062 | 1.0057 | 2.1598 | |
| HCC1806 | TNBC | Basal A | JNK-IN-5A | JNK | JNK | 0.00853 | uM | 12239.144 | 1.0538 | 1.0491 | 2.1598 | |
| HCC1806 | TNBC | Basal A | JNK-IN-5A | JNK | JNK | 0.0427 | uM | 12239.144 | 1.0849 | 1.0769 | 2.1598 | |
| HCC1806 | TNBC | Basal A | JNK-IN-5A | JNK | JNK | 0.213 | uM | 12239.144 | 1.0048 | 1.0045 | 2.1598 | |
| HCC1806 | TNBC | Basal A | JNK-IN-5A | JNK | JNK | 1.07 | uM | 12239.144 | 0.8580 | 0.8631 | 2.1598 | |
| HCC1806 | TNBC | Basal A | JNK-IN-5A | JNK | JNK | 5.33 | uM | 12239.144 | 0.7001 | 0.6956 | 2.1598 | |
| HCC1806 | TNBC | Basal A | JNK-IN-5A | JNK | JNK | 26.7 | uM | 12239.144 | 1.0334 | 1.0306 | 2.1598 | |
| HCC1806 | TNBC | Basal A | JNK-IN-5A | JNK | JNK | 133 | uM | 12239.144 | 0.4271 | 0.3489 | 2.1598 | |
| HCC1937 | TNBC | Basal A | JNK-IN-5A | JNK | JNK | 0.000341 | uM | 11849.144 | 0.9824 | 0.9751 | 1.4131 | |
| HCC1937 | TNBC | Basal A | JNK-IN-5A | JNK | JNK | 0.00171 | uM | 11849.144 | 1.0028 | 1.0039 | 1.4131 |