Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
Download: Excel (XLSX), Comma-separated (CSV)
| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC1937 | TNBC | Basal A | JNK-IN-5A | JNK | JNK | 0.00853 | uM | 11849.144 | 1.0172 | 1.0243 | 1.4131 | |
| HCC1937 | TNBC | Basal A | JNK-IN-5A | JNK | JNK | 0.0427 | uM | 11849.144 | 1.0705 | 1.0988 | 1.4131 | |
| HCC1937 | TNBC | Basal A | JNK-IN-5A | JNK | JNK | 0.213 | uM | 11849.144 | 1.0240 | 1.0338 | 1.4131 | |
| HCC1937 | TNBC | Basal A | JNK-IN-5A | JNK | JNK | 1.07 | uM | 11849.144 | 0.9440 | 0.9201 | 1.4131 | |
| HCC1937 | TNBC | Basal A | JNK-IN-5A | JNK | JNK | 5.33 | uM | 11849.144 | 0.7644 | 0.6536 | 1.4131 | |
| HCC1937 | TNBC | Basal A | JNK-IN-5A | JNK | JNK | 26.7 | uM | 11849.144 | 1.0262 | 1.0369 | 1.4131 | |
| HCC1937 | TNBC | Basal A | JNK-IN-5A | JNK | JNK | 133 | uM | 11849.144 | 0.7499 | 0.6314 | 1.4131 | |
| HCC1954 | HER2amp | Basal A | JNK-IN-5A | JNK | JNK | 0.000341 | uM | 11055.144 | 0.9764 | 0.9716 | 1.6716 | |
| HCC1954 | HER2amp | Basal A | JNK-IN-5A | JNK | JNK | 0.00171 | uM | 11055.144 | 0.9595 | 0.9512 | 1.6716 | |
| HCC1954 | HER2amp | Basal A | JNK-IN-5A | JNK | JNK | 0.00853 | uM | 11055.144 | 0.9714 | 0.9656 | 1.6716 | |
| HCC1954 | HER2amp | Basal A | JNK-IN-5A | JNK | JNK | 0.0427 | uM | 11055.144 | 0.9317 | 0.9171 | 1.6716 | |
| HCC1954 | HER2amp | Basal A | JNK-IN-5A | JNK | JNK | 0.213 | uM | 11055.144 | 0.7771 | 0.7199 | 1.6716 | |
| HCC1954 | HER2amp | Basal A | JNK-IN-5A | JNK | JNK | 1.07 | uM | 11055.144 | 0.6157 | 0.4963 | 1.6716 | |
| HCC1954 | HER2amp | Basal A | JNK-IN-5A | JNK | JNK | 5.33 | uM | 11055.144 | 0.4120 | 0.1767 | 1.6716 | |
| HCC1954 | HER2amp | Basal A | JNK-IN-5A | JNK | JNK | 26.7 | uM | 11055.144 | 0.5669 | 0.4243 | 1.6716 | |
| HCC1954 | HER2amp | Basal A | JNK-IN-5A | JNK | JNK | 133 | uM | 11055.144 | 0.1199 | -0.4376 | 1.6716 | |
| HCC2185 | TNBC | Luminal | JNK-IN-5A | JNK | JNK | 0.000341 | uM | 10996.144 | 0.9848 | 0.9411 | 0.5116 | |
| HCC2185 | TNBC | Luminal | JNK-IN-5A | JNK | JNK | 0.00171 | uM | 10996.144 | 0.9495 | 0.8072 | 0.5116 | |
| HCC2185 | TNBC | Luminal | JNK-IN-5A | JNK | JNK | 0.00853 | uM | 10996.144 | 0.9879 | 0.9529 | 0.5116 | |
| HCC2185 | TNBC | Luminal | JNK-IN-5A | JNK | JNK | 0.0427 | uM | 10996.144 | 1.0192 | 1.0758 | 0.5116 | |
| HCC2185 | TNBC | Luminal | JNK-IN-5A | JNK | JNK | 0.213 | uM | 10996.144 | 0.9602 | 0.8475 | 0.5116 | |
| HCC2185 | TNBC | Luminal | JNK-IN-5A | JNK | JNK | 1.07 | uM | 10996.144 | 0.9946 | 0.9791 | 0.5116 | |
| HCC2185 | TNBC | Luminal | JNK-IN-5A | JNK | JNK | 5.33 | uM | 10996.144 | 0.6843 | -0.0471 | 0.5116 | |
| HCC2185 | TNBC | Luminal | JNK-IN-5A | JNK | JNK | 26.7 | uM | 10996.144 | 1.0324 | 1.1284 | 0.5116 | |
| HCC2185 | TNBC | Luminal | JNK-IN-5A | JNK | JNK | 133 | uM | 10996.144 | 0.8228 | 0.3659 | 0.5116 |