Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
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SUM149PT | TNBC | Basal B | LBH589 | HDAC | HDAC | 0.0000853 | uM | 10819.154 | 1.0119 | 1.0115 | 2.0680 | |
SUM149PT | TNBC | Basal B | LBH589 | HDAC | HDAC | 0.000427 | uM | 10819.154 | 0.9356 | 0.9366 | 2.0680 | |
SUM149PT | TNBC | Basal B | LBH589 | HDAC | HDAC | 0.00213 | uM | 10819.154 | 0.9657 | 0.9665 | 2.0680 | |
SUM149PT | TNBC | Basal B | LBH589 | HDAC | HDAC | 0.0107 | uM | 10819.154 | 0.9812 | 0.9817 | 2.0680 | |
SUM149PT | TNBC | Basal B | LBH589 | HDAC | HDAC | 0.0533 | uM | 10819.154 | 1.0511 | 1.0488 | 2.0680 | |
SUM149PT | TNBC | Basal B | LBH589 | HDAC | HDAC | 0.267 | uM | 10819.154 | 0.8500 | 0.8488 | 2.0680 | |
SUM149PT | TNBC | Basal B | LBH589 | HDAC | HDAC | 1.33 | uM | 10819.154 | 0.0739 | -0.4326 | 2.0680 | |
SUM149PT | TNBC | Basal B | LBH589 | HDAC | HDAC | 6.67 | uM | 10819.154 | 0.0095 | -0.7898 | 2.0680 | |
SUM149PT | TNBC | Basal B | LBH589 | HDAC | HDAC | 33.3 | uM | 10819.154 | 0.0025 | -0.8887 | 2.0680 | |
SUM149PT | TNBC | Basal B | LBH589 | HDAC | HDAC | 0.0000853 | uM | 11937.154 | 0.9273 | 0.9412 | 2.5304 | |
SUM149PT | TNBC | Basal B | LBH589 | HDAC | HDAC | 0.000427 | uM | 11937.154 | 0.9543 | 0.9634 | 2.5304 | |
SUM149PT | TNBC | Basal B | LBH589 | HDAC | HDAC | 0.00213 | uM | 11937.154 | 0.9649 | 0.9720 | 2.5304 | |
SUM149PT | TNBC | Basal B | LBH589 | HDAC | HDAC | 0.0107 | uM | 11937.154 | 0.9784 | 0.9828 | 2.5304 | |
SUM149PT | TNBC | Basal B | LBH589 | HDAC | HDAC | 0.0533 | uM | 11937.154 | 0.8046 | 0.8353 | 2.5304 | |
SUM149PT | TNBC | Basal B | LBH589 | HDAC | HDAC | 0.267 | uM | 11937.154 | 0.2613 | 0.1767 | 2.5304 | |
SUM149PT | TNBC | Basal B | LBH589 | HDAC | HDAC | 1.33 | uM | 11937.154 | 0.0209 | -0.5662 | 2.5304 | |
SUM149PT | TNBC | Basal B | LBH589 | HDAC | HDAC | 6.67 | uM | 11937.154 | 0.0086 | -0.6952 | 2.5304 | |
SUM149PT | TNBC | Basal B | LBH589 | HDAC | HDAC | 33.3 | uM | 11937.154 | 0.0082 | -0.7005 | 2.5304 | |
SUM159PT | TNBC | Basal B | LBH589 | HDAC | HDAC | 0.0000853 | uM | 11057.154 | 0.9492 | 0.9731 | 3.8498 | |
SUM159PT | TNBC | Basal B | LBH589 | HDAC | HDAC | 0.000427 | uM | 11057.154 | 0.9154 | 0.9546 | 3.8498 | |
SUM159PT | TNBC | Basal B | LBH589 | HDAC | HDAC | 0.00213 | uM | 11057.154 | 1.0972 | 1.0488 | 3.8498 | |
SUM159PT | TNBC | Basal B | LBH589 | HDAC | HDAC | 0.0107 | uM | 11057.154 | 0.9752 | 0.9870 | 3.8498 | |
SUM159PT | TNBC | Basal B | LBH589 | HDAC | HDAC | 0.0533 | uM | 11057.154 | 0.7349 | 0.8462 | 3.8498 | |
SUM159PT | TNBC | Basal B | LBH589 | HDAC | HDAC | 0.267 | uM | 11057.154 | 0.2971 | 0.4593 | 3.8498 | |
SUM159PT | TNBC | Basal B | LBH589 | HDAC | HDAC | 1.33 | uM | 11057.154 | 0.0025 | -0.5782 | 3.8498 |