Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)

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Cell Clinical Subtype Transcriptional Subtype Small Molecule Antibody Perturbagen Target Perturbagen Class Perturbagen Concentration Perturbagen Conc Unit Biological Replicate ID Relative Cell Count Normalized Growth Rate Inhibition Value Nominal Division Rate
SUM149PT
TNBC
Basal B
LBH589
HDAC
HDAC
0.0000853
uM
10819.154
1.0119 1.0115 2.0680
SUM149PT
TNBC
Basal B
LBH589
HDAC
HDAC
0.000427
uM
10819.154
0.9356 0.9366 2.0680
SUM149PT
TNBC
Basal B
LBH589
HDAC
HDAC
0.00213
uM
10819.154
0.9657 0.9665 2.0680
SUM149PT
TNBC
Basal B
LBH589
HDAC
HDAC
0.0107
uM
10819.154
0.9812 0.9817 2.0680
SUM149PT
TNBC
Basal B
LBH589
HDAC
HDAC
0.0533
uM
10819.154
1.0511 1.0488 2.0680
SUM149PT
TNBC
Basal B
LBH589
HDAC
HDAC
0.267
uM
10819.154
0.8500 0.8488 2.0680
SUM149PT
TNBC
Basal B
LBH589
HDAC
HDAC
1.33
uM
10819.154
0.0739 -0.4326 2.0680
SUM149PT
TNBC
Basal B
LBH589
HDAC
HDAC
6.67
uM
10819.154
0.0095 -0.7898 2.0680
SUM149PT
TNBC
Basal B
LBH589
HDAC
HDAC
33.3
uM
10819.154
0.0025 -0.8887 2.0680
SUM149PT
TNBC
Basal B
LBH589
HDAC
HDAC
0.0000853
uM
11937.154
0.9273 0.9412 2.5304
SUM149PT
TNBC
Basal B
LBH589
HDAC
HDAC
0.000427
uM
11937.154
0.9543 0.9634 2.5304
SUM149PT
TNBC
Basal B
LBH589
HDAC
HDAC
0.00213
uM
11937.154
0.9649 0.9720 2.5304
SUM149PT
TNBC
Basal B
LBH589
HDAC
HDAC
0.0107
uM
11937.154
0.9784 0.9828 2.5304
SUM149PT
TNBC
Basal B
LBH589
HDAC
HDAC
0.0533
uM
11937.154
0.8046 0.8353 2.5304
SUM149PT
TNBC
Basal B
LBH589
HDAC
HDAC
0.267
uM
11937.154
0.2613 0.1767 2.5304
SUM149PT
TNBC
Basal B
LBH589
HDAC
HDAC
1.33
uM
11937.154
0.0209 -0.5662 2.5304
SUM149PT
TNBC
Basal B
LBH589
HDAC
HDAC
6.67
uM
11937.154
0.0086 -0.6952 2.5304
SUM149PT
TNBC
Basal B
LBH589
HDAC
HDAC
33.3
uM
11937.154
0.0082 -0.7005 2.5304
SUM159PT
TNBC
Basal B
LBH589
HDAC
HDAC
0.0000853
uM
11057.154
0.9492 0.9731 3.8498
SUM159PT
TNBC
Basal B
LBH589
HDAC
HDAC
0.000427
uM
11057.154
0.9154 0.9546 3.8498
SUM159PT
TNBC
Basal B
LBH589
HDAC
HDAC
0.00213
uM
11057.154
1.0972 1.0488 3.8498
SUM159PT
TNBC
Basal B
LBH589
HDAC
HDAC
0.0107
uM
11057.154
0.9752 0.9870 3.8498
SUM159PT
TNBC
Basal B
LBH589
HDAC
HDAC
0.0533
uM
11057.154
0.7349 0.8462 3.8498
SUM159PT
TNBC
Basal B
LBH589
HDAC
HDAC
0.267
uM
11057.154
0.2971 0.4593 3.8498
SUM159PT
TNBC
Basal B
LBH589
HDAC
HDAC
1.33
uM
11057.154
0.0025 -0.5782 3.8498