Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SUM52PE | HR+ | Luminal | Ixabepilone | TUBB | TUBB | 39.4 | uM | 7541.095 | 0.0014 | -0.9787 | 1.4542 | |
| T47D | HR+ | Luminal | Ixabepilone | TUBB | TUBB | 0.000101 | uM | 7542.095 | 1.0299 | 1.0462 | 1.2904 | |
| T47D | HR+ | Luminal | Ixabepilone | TUBB | TUBB | 0.000505 | uM | 7542.095 | 0.9810 | 0.9705 | 1.2904 | |
| T47D | HR+ | Luminal | Ixabepilone | TUBB | TUBB | 0.00252 | uM | 7542.095 | 0.9882 | 0.9818 | 1.2904 | |
| T47D | HR+ | Luminal | Ixabepilone | TUBB | TUBB | 0.0126 | uM | 7542.095 | 0.6872 | 0.4955 | 1.2904 | |
| T47D | HR+ | Luminal | Ixabepilone | TUBB | TUBB | 0.0631 | uM | 7542.095 | 0.3682 | -0.0780 | 1.2904 | |
| T47D | HR+ | Luminal | Ixabepilone | TUBB | TUBB | 0.316 | uM | 7542.095 | 0.2481 | -0.3209 | 1.2904 | |
| T47D | HR+ | Luminal | Ixabepilone | TUBB | TUBB | 1.58 | uM | 7542.095 | 0.3528 | -0.1080 | 1.2904 | |
| T47D | HR+ | Luminal | Ixabepilone | TUBB | TUBB | 7.89 | uM | 7542.095 | 0.3563 | -0.1011 | 1.2904 | |
| T47D | HR+ | Luminal | Ixabepilone | TUBB | TUBB | 39.4 | uM | 7542.095 | 0.0073 | -0.9559 | 1.2904 | |
| T47D | HR+ | Luminal | Ixabepilone | TUBB | TUBB | 0.000101 | uM | 7543.095 | 1.0748 | 1.1255 | 1.1854 | |
| T47D | HR+ | Luminal | Ixabepilone | TUBB | TUBB | 0.000505 | uM | 7543.095 | 1.0066 | 1.0111 | 1.1854 | |
| T47D | HR+ | Luminal | Ixabepilone | TUBB | TUBB | 0.00252 | uM | 7543.095 | 0.6564 | 0.4022 | 1.1854 | |
| T47D | HR+ | Luminal | Ixabepilone | TUBB | TUBB | 0.0126 | uM | 7543.095 | 0.4773 | 0.0716 | 1.1854 | |
| T47D | HR+ | Luminal | Ixabepilone | TUBB | TUBB | 0.0631 | uM | 7543.095 | 0.4126 | -0.0522 | 1.1854 | |
| T47D | HR+ | Luminal | Ixabepilone | TUBB | TUBB | 0.316 | uM | 7543.095 | 0.3839 | -0.1082 | 1.1854 | |
| T47D | HR+ | Luminal | Ixabepilone | TUBB | TUBB | 1.58 | uM | 7543.095 | 0.6904 | 0.4632 | 1.1854 | |
| T47D | HR+ | Luminal | Ixabepilone | TUBB | TUBB | 7.89 | uM | 7543.095 | 0.6292 | 0.3529 | 1.1854 | |
| T47D | HR+ | Luminal | Ixabepilone | TUBB | TUBB | 39.4 | uM | 7543.095 | 0.0005 | -0.9968 | 1.1854 | |
| T47DKBLUC | Unknown | Unknown | Ixabepilone | TUBB | TUBB | 0.000101 | uM | 7544.095 | 0.9489 | 0.8995 | 1.0175 | |
| T47DKBLUC | Unknown | Unknown | Ixabepilone | TUBB | TUBB | 0.000505 | uM | 7544.095 | 0.8663 | 0.7368 | 1.0175 | |
| T47DKBLUC | Unknown | Unknown | Ixabepilone | TUBB | TUBB | 0.00252 | uM | 7544.095 | 0.9661 | 0.9333 | 1.0175 | |
| T47DKBLUC | Unknown | Unknown | Ixabepilone | TUBB | TUBB | 0.0126 | uM | 7544.095 | 0.8195 | 0.6445 | 1.0175 | |
| T47DKBLUC | Unknown | Unknown | Ixabepilone | TUBB | TUBB | 0.0631 | uM | 7544.095 | 0.5486 | 0.1086 | 1.0175 | |
| T47DKBLUC | Unknown | Unknown | Ixabepilone | TUBB | TUBB | 0.316 | uM | 7544.095 | 0.4705 | -0.0468 | 1.0175 |