Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC1143 | TNBC | Basal A | GSK461364 | PLK1 | PLK | 33.3 | uM | 7810.001 | 0.1152 | -0.8157 | 0.9063 | |
| HCC1143 | TNBC | Basal A | GSK461364 | PLK1 | PLK | 0.0000853 | uM | 9233.001 | 1.0069 | 1.0141 | 0.9839 | |
| HCC1143 | TNBC | Basal A | GSK461364 | PLK1 | PLK | 0.000427 | uM | 9233.001 | 0.9495 | 0.8974 | 0.9839 | |
| HCC1143 | TNBC | Basal A | GSK461364 | PLK1 | PLK | 0.00213 | uM | 9233.001 | 1.0963 | 1.1959 | 0.9839 | |
| HCC1143 | TNBC | Basal A | GSK461364 | PLK1 | PLK | 0.0107 | uM | 9233.001 | 0.8281 | 0.6510 | 0.9839 | |
| HCC1143 | TNBC | Basal A | GSK461364 | PLK1 | PLK | 0.0533 | uM | 9233.001 | 0.6843 | 0.3600 | 0.9839 | |
| HCC1143 | TNBC | Basal A | GSK461364 | PLK1 | PLK | 0.267 | uM | 9233.001 | 0.6589 | 0.3089 | 0.9839 | |
| HCC1143 | TNBC | Basal A | GSK461364 | PLK1 | PLK | 1.33 | uM | 9233.001 | 0.6012 | 0.1924 | 0.9839 | |
| HCC1143 | TNBC | Basal A | GSK461364 | PLK1 | PLK | 6.67 | uM | 9233.001 | 0.4730 | -0.0656 | 0.9839 | |
| HCC1143 | TNBC | Basal A | GSK461364 | PLK1 | PLK | 33.3 | uM | 9233.001 | 0.1601 | -0.6892 | 0.9839 | |
| HCC1187 | TNBC | Basal A | GSK461364 | PLK1 | PLK | 0.0000853 | uM | 7811.001 | 1.0105 | 1.0472 | 0.4464 | |
| HCC1187 | TNBC | Basal A | GSK461364 | PLK1 | PLK | 0.000427 | uM | 7811.001 | 0.9801 | 0.9118 | 0.4464 | |
| HCC1187 | TNBC | Basal A | GSK461364 | PLK1 | PLK | 0.00213 | uM | 7811.001 | 0.9386 | 0.7354 | 0.4464 | |
| HCC1187 | TNBC | Basal A | GSK461364 | PLK1 | PLK | 0.0107 | uM | 7811.001 | 0.9866 | 0.9404 | 0.4464 | |
| HCC1187 | TNBC | Basal A | GSK461364 | PLK1 | PLK | 0.0533 | uM | 7811.001 | 0.3552 | -0.8032 | 0.4464 | |
| HCC1187 | TNBC | Basal A | GSK461364 | PLK1 | PLK | 0.267 | uM | 7811.001 | 0.2257 | -0.9287 | 0.4464 | |
| HCC1187 | TNBC | Basal A | GSK461364 | PLK1 | PLK | 1.33 | uM | 7811.001 | 0.4258 | -0.7045 | 0.4464 | |
| HCC1187 | TNBC | Basal A | GSK461364 | PLK1 | PLK | 6.67 | uM | 7811.001 | 0.4413 | -0.6799 | 0.4464 | |
| HCC1187 | TNBC | Basal A | GSK461364 | PLK1 | PLK | 33.3 | uM | 7811.001 | 0.3902 | -0.7570 | 0.4464 | |
| HCC1187 | TNBC | Basal A | GSK461364 | PLK1 | PLK | 0.0000853 | uM | 7812.001 | 1.0713 | 1.1418 | 1.0060 | |
| HCC1187 | TNBC | Basal A | GSK461364 | PLK1 | PLK | 0.000427 | uM | 7812.001 | 1.1023 | 1.2032 | 1.0060 | |
| HCC1187 | TNBC | Basal A | GSK461364 | PLK1 | PLK | 0.00213 | uM | 7812.001 | 1.0409 | 1.0812 | 1.0060 | |
| HCC1187 | TNBC | Basal A | GSK461364 | PLK1 | PLK | 0.0107 | uM | 7812.001 | 1.0473 | 1.0939 | 1.0060 | |
| HCC1187 | TNBC | Basal A | GSK461364 | PLK1 | PLK | 0.0533 | uM | 7812.001 | 0.1209 | -0.7551 | 1.0060 | |
| HCC1187 | TNBC | Basal A | GSK461364 | PLK1 | PLK | 0.267 | uM | 7812.001 | 0.2206 | -0.5548 | 1.0060 |