Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| T47DKBLUC | Unknown | Unknown | GSK1838705A | IGF1R | RTK | 0.00171 | uM | 7546.091 | 1.0291 | 1.0637 | 0.9137 | |
| T47DKBLUC | Unknown | Unknown | GSK1838705A | IGF1R | RTK | 0.00853 | uM | 7546.091 | 0.9956 | 0.9904 | 0.9137 | |
| T47DKBLUC | Unknown | Unknown | GSK1838705A | IGF1R | RTK | 0.0427 | uM | 7546.091 | 1.0254 | 1.0556 | 0.9137 | |
| T47DKBLUC | Unknown | Unknown | GSK1838705A | IGF1R | RTK | 0.213 | uM | 7546.091 | 1.0062 | 1.0135 | 0.9137 | |
| T47DKBLUC | Unknown | Unknown | GSK1838705A | IGF1R | RTK | 1.07 | uM | 7546.091 | 0.8490 | 0.6719 | 0.9137 | |
| T47DKBLUC | Unknown | Unknown | GSK1838705A | IGF1R | RTK | 5.33 | uM | 7546.091 | 0.8679 | 0.7127 | 0.9137 | |
| T47DKBLUC | Unknown | Unknown | GSK1838705A | IGF1R | RTK | 26.7 | uM | 7546.091 | 0.8846 | 0.7488 | 0.9137 | |
| T47DKBLUC | Unknown | Unknown | GSK1838705A | IGF1R | RTK | 133 | uM | 7546.091 | 0.8996 | 0.7813 | 0.9137 | |
| T47DKBLUC | Unknown | Unknown | GSK1838705A | IGF1R | RTK | 0.000171 | uM | 7546.098 | 0.9732 | 0.9371 | 0.8495 | |
| T47DKBLUC | Unknown | Unknown | GSK1838705A | IGF1R | RTK | 0.000853 | uM | 7546.098 | 1.0423 | 1.0999 | 0.8495 | |
| T47DKBLUC | Unknown | Unknown | GSK1838705A | IGF1R | RTK | 0.00427 | uM | 7546.098 | 0.9901 | 0.9767 | 0.8495 | |
| T47DKBLUC | Unknown | Unknown | GSK1838705A | IGF1R | RTK | 0.0213 | uM | 7546.098 | 1.0103 | 1.0243 | 0.8495 | |
| T47DKBLUC | Unknown | Unknown | GSK1838705A | IGF1R | RTK | 0.107 | uM | 7546.098 | 0.9827 | 0.9593 | 0.8495 | |
| T47DKBLUC | Unknown | Unknown | GSK1838705A | IGF1R | RTK | 0.533 | uM | 7546.098 | 0.9170 | 0.8061 | 0.8495 | |
| T47DKBLUC | Unknown | Unknown | GSK1838705A | IGF1R | RTK | 2.67 | uM | 7546.098 | 0.8232 | 0.5906 | 0.8495 | |
| T47DKBLUC | Unknown | Unknown | GSK1838705A | IGF1R | RTK | 13.3 | uM | 7546.098 | 0.8134 | 0.5684 | 0.8495 | |
| T47DKBLUC | Unknown | Unknown | GSK1838705A | IGF1R | RTK | 66.7 | uM | 7546.098 | 0.8105 | 0.5617 | 0.8495 | |
| UACC-812 | HER2amp | Luminal | GSK1838705A | IGF1R | RTK | 0.000171 | uM | 7547.092 | 0.9671 | 0.9333 | 0.9866 | |
| UACC-812 | HER2amp | Luminal | GSK1838705A | IGF1R | RTK | 0.000853 | uM | 7547.092 | 0.7548 | 0.5037 | 0.9866 | |
| UACC-812 | HER2amp | Luminal | GSK1838705A | IGF1R | RTK | 0.00427 | uM | 7547.092 | 0.9411 | 0.8805 | 0.9866 | |
| UACC-812 | HER2amp | Luminal | GSK1838705A | IGF1R | RTK | 0.0213 | uM | 7547.092 | 0.8589 | 0.7142 | 0.9866 | |
| UACC-812 | HER2amp | Luminal | GSK1838705A | IGF1R | RTK | 0.107 | uM | 7547.092 | 0.8992 | 0.7958 | 0.9866 | |
| UACC-812 | HER2amp | Luminal | GSK1838705A | IGF1R | RTK | 0.533 | uM | 7547.092 | 0.7908 | 0.5766 | 0.9866 | |
| UACC-812 | HER2amp | Luminal | GSK1838705A | IGF1R | RTK | 2.67 | uM | 7547.092 | 0.8722 | 0.7411 | 0.9866 | |
| UACC-812 | HER2amp | Luminal | GSK1838705A | IGF1R | RTK | 13.3 | uM | 7547.092 | 0.7652 | 0.5248 | 0.9866 |