Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SUM159PT | TNBC | Basal B | GW843682X | PLK | PLK | 1.33 | uM | 10520.139 | 0.7199 | 0.8277 | 3.6491 | |
| SUM159PT | TNBC | Basal B | GW843682X | PLK | PLK | 6.67 | uM | 10520.139 | 0.5483 | 0.6963 | 3.6491 | |
| SUM159PT | TNBC | Basal B | GW843682X | PLK | PLK | 33.3 | uM | 10520.139 | 0.5007 | 0.6546 | 3.6491 | |
| SUM225CWN | HER2amp | Basal A | GW843682X | PLK | PLK | 0.0000853 | uM | 10579.139 | 1.0174 | 1.0309 | 1.1260 | |
| SUM225CWN | HER2amp | Basal A | GW843682X | PLK | PLK | 0.000427 | uM | 10579.139 | 0.9201 | 0.8574 | 1.1260 | |
| SUM225CWN | HER2amp | Basal A | GW843682X | PLK | PLK | 0.00213 | uM | 10579.139 | 0.8662 | 0.7604 | 1.1260 | |
| SUM225CWN | HER2amp | Basal A | GW843682X | PLK | PLK | 0.0107 | uM | 10579.139 | 0.9675 | 0.9421 | 1.1260 | |
| SUM225CWN | HER2amp | Basal A | GW843682X | PLK | PLK | 0.0533 | uM | 10579.139 | 1.0117 | 1.0209 | 1.1260 | |
| SUM225CWN | HER2amp | Basal A | GW843682X | PLK | PLK | 0.267 | uM | 10579.139 | 0.8966 | 0.8152 | 1.1260 | |
| SUM225CWN | HER2amp | Basal A | GW843682X | PLK | PLK | 1.33 | uM | 10579.139 | 1.0053 | 1.0094 | 1.1260 | |
| SUM225CWN | HER2amp | Basal A | GW843682X | PLK | PLK | 6.67 | uM | 10579.139 | 0.9758 | 0.9570 | 1.1260 | |
| SUM225CWN | HER2amp | Basal A | GW843682X | PLK | PLK | 33.3 | uM | 10579.139 | 0.8938 | 0.8101 | 1.1260 | |
| UACC-812 | HER2amp | Luminal | GW843682X | PLK | PLK | 0.0000853 | uM | 10580.139 | 1.0373 | 1.0790 | 0.9460 | |
| UACC-812 | HER2amp | Luminal | GW843682X | PLK | PLK | 0.000427 | uM | 10580.139 | 0.9056 | 0.8011 | 0.9460 | |
| UACC-812 | HER2amp | Luminal | GW843682X | PLK | PLK | 0.00213 | uM | 10580.139 | 0.9435 | 0.8808 | 0.9460 | |
| UACC-812 | HER2amp | Luminal | GW843682X | PLK | PLK | 0.0107 | uM | 10580.139 | 1.0196 | 1.0415 | 0.9460 | |
| UACC-812 | HER2amp | Luminal | GW843682X | PLK | PLK | 0.0533 | uM | 10580.139 | 1.0388 | 1.0822 | 0.9460 | |
| UACC-812 | HER2amp | Luminal | GW843682X | PLK | PLK | 0.267 | uM | 10580.139 | 0.9292 | 0.8506 | 0.9460 | |
| UACC-812 | HER2amp | Luminal | GW843682X | PLK | PLK | 1.33 | uM | 10580.139 | 1.0405 | 1.0856 | 0.9460 | |
| UACC-812 | HER2amp | Luminal | GW843682X | PLK | PLK | 6.67 | uM | 10580.139 | 0.9517 | 0.8981 | 0.9460 | |
| UACC-812 | HER2amp | Luminal | GW843682X | PLK | PLK | 33.3 | uM | 10580.139 | 1.0191 | 1.0403 | 0.9460 | |
| 184A1 | NM | Basal | Ibandronate | FDPS | 0.00384 | uM | 12509.143 | 1.0129 | 1.0193 | 1.3392 | ||
| 184A1 | NM | Basal | Ibandronate | FDPS | 0.0192 | uM | 12509.143 | 1.0488 | 1.0724 | 1.3392 | ||
| 184A1 | NM | Basal | Ibandronate | FDPS | 0.096 | uM | 12509.143 | 0.9543 | 0.9314 | 1.3392 | ||
| 184A1 | NM | Basal | Ibandronate | FDPS | 0.48 | uM | 12509.143 | 0.9730 | 0.9596 | 1.3392 |