Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 184A1 | NM | Basal | Ibandronate | FDPS | 2.4 | uM | 12509.143 | 0.9985 | 0.9977 | 1.3392 | ||
| 184A1 | NM | Basal | Ibandronate | FDPS | 12 | uM | 12509.143 | 0.9557 | 0.9335 | 1.3392 | ||
| 184A1 | NM | Basal | Ibandronate | FDPS | 60 | uM | 12509.143 | 0.9188 | 0.8775 | 1.3392 | ||
| 184A1 | NM | Basal | Ibandronate | FDPS | 300 | uM | 12509.143 | 0.3795 | -0.0299 | 1.3392 | ||
| 184A1 | NM | Basal | Ibandronate | FDPS | 1500 | uM | 12509.143 | 0.0148 | -0.9140 | 1.3392 | ||
| 184B5 | NM | Basal | Ibandronate | FDPS | 0.00384 | uM | 12566.143 | 1.0055 | 1.0067 | 1.6413 | ||
| 184B5 | NM | Basal | Ibandronate | FDPS | 0.0192 | uM | 12566.143 | 0.9431 | 0.9299 | 1.6413 | ||
| 184B5 | NM | Basal | Ibandronate | FDPS | 0.096 | uM | 12566.143 | 0.9818 | 0.9777 | 1.6413 | ||
| 184B5 | NM | Basal | Ibandronate | FDPS | 0.48 | uM | 12566.143 | 1.0523 | 1.0631 | 1.6413 | ||
| 184B5 | NM | Basal | Ibandronate | FDPS | 2.4 | uM | 12566.143 | 0.9924 | 0.9907 | 1.6413 | ||
| 184B5 | NM | Basal | Ibandronate | FDPS | 12 | uM | 12566.143 | 1.0015 | 1.0018 | 1.6413 | ||
| 184B5 | NM | Basal | Ibandronate | FDPS | 60 | uM | 12566.143 | 0.9815 | 0.9773 | 1.6413 | ||
| 184B5 | NM | Basal | Ibandronate | FDPS | 300 | uM | 12566.143 | 0.4970 | 0.3063 | 1.6413 | ||
| 184B5 | NM | Basal | Ibandronate | FDPS | 1500 | uM | 12566.143 | 0.0171 | -0.8325 | 1.6413 | ||
| 600MPE | HR+ | Luminal | Ibandronate | FDPS | 0.00384 | uM | 12224.143 | 0.9810 | 0.9545 | 0.8349 | ||
| 600MPE | HR+ | Luminal | Ibandronate | FDPS | 0.0192 | uM | 12224.143 | 0.9837 | 0.9609 | 0.8349 | ||
| 600MPE | HR+ | Luminal | Ibandronate | FDPS | 0.096 | uM | 12224.143 | 0.9989 | 0.9974 | 0.8349 | ||
| 600MPE | HR+ | Luminal | Ibandronate | FDPS | 0.48 | uM | 12224.143 | 0.9595 | 0.9034 | 0.8349 | ||
| 600MPE | HR+ | Luminal | Ibandronate | FDPS | 2.4 | uM | 12224.143 | 0.9952 | 0.9884 | 0.8349 | ||
| 600MPE | HR+ | Luminal | Ibandronate | FDPS | 12 | uM | 12224.143 | 0.9838 | 0.9613 | 0.8349 | ||
| 600MPE | HR+ | Luminal | Ibandronate | FDPS | 60 | uM | 12224.143 | 0.9879 | 0.9710 | 0.8349 | ||
| 600MPE | HR+ | Luminal | Ibandronate | FDPS | 300 | uM | 12224.143 | 0.3876 | -0.3574 | 0.8349 | ||
| 600MPE | HR+ | Luminal | Ibandronate | FDPS | 1500 | uM | 12224.143 | 0.3583 | -0.4151 | 0.8349 | ||
| AU565 | HER2amp | Luminal | Ibandronate | FDPS | 0.00384 | uM | 10880.143 | 0.9560 | 0.9448 | 1.6077 | ||
| AU565 | HER2amp | Luminal | Ibandronate | FDPS | 0.0192 | uM | 10880.143 | 0.9364 | 0.9199 | 1.6077 |