Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
Download: Excel (XLSX), Comma-separated (CSV)
| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HBL-100 | Unknown | Unknown | GSK461364 | PLK1 | PLK | 0.000427 | uM | 7808.001 | 1.0178 | 1.0140 | 2.5321 | |
| HBL-100 | Unknown | Unknown | GSK461364 | PLK1 | PLK | 0.00213 | uM | 7808.001 | 0.4140 | 0.4117 | 2.5321 | |
| HBL-100 | Unknown | Unknown | GSK461364 | PLK1 | PLK | 0.0107 | uM | 7808.001 | 0.1778 | 0.0111 | 2.5321 | |
| HBL-100 | Unknown | Unknown | GSK461364 | PLK1 | PLK | 0.0533 | uM | 7808.001 | 0.1821 | 0.0208 | 2.5321 | |
| HBL-100 | Unknown | Unknown | GSK461364 | PLK1 | PLK | 0.267 | uM | 7808.001 | 0.2966 | 0.2376 | 2.5321 | |
| HBL-100 | Unknown | Unknown | GSK461364 | PLK1 | PLK | 1.33 | uM | 7808.001 | 0.4237 | 0.4248 | 2.5321 | |
| HBL-100 | Unknown | Unknown | GSK461364 | PLK1 | PLK | 6.67 | uM | 7808.001 | 0.3431 | 0.3108 | 2.5321 | |
| HBL-100 | Unknown | Unknown | GSK461364 | PLK1 | PLK | 33.3 | uM | 7808.001 | 0.0038 | -0.7793 | 2.5321 | |
| HBL-100 | Unknown | Unknown | GSK461364 | PLK1 | PLK | 0.0000853 | uM | 9226.001 | 0.9806 | 0.9853 | 2.6569 | |
| HBL-100 | Unknown | Unknown | GSK461364 | PLK1 | PLK | 0.000427 | uM | 9226.001 | 0.9926 | 0.9944 | 2.6569 | |
| HBL-100 | Unknown | Unknown | GSK461364 | PLK1 | PLK | 0.00213 | uM | 9226.001 | 0.9779 | 0.9833 | 2.6569 | |
| HBL-100 | Unknown | Unknown | GSK461364 | PLK1 | PLK | 0.0107 | uM | 9226.001 | 0.5643 | 0.6125 | 2.6569 | |
| HBL-100 | Unknown | Unknown | GSK461364 | PLK1 | PLK | 0.0533 | uM | 9226.001 | 0.2268 | 0.1442 | 2.6569 | |
| HBL-100 | Unknown | Unknown | GSK461364 | PLK1 | PLK | 0.267 | uM | 9226.001 | 0.3109 | 0.2884 | 2.6569 | |
| HBL-100 | Unknown | Unknown | GSK461364 | PLK1 | PLK | 1.33 | uM | 9226.001 | 0.4420 | 0.4709 | 2.6569 | |
| HBL-100 | Unknown | Unknown | GSK461364 | PLK1 | PLK | 6.67 | uM | 9226.001 | 0.4502 | 0.4811 | 2.6569 | |
| HBL-100 | Unknown | Unknown | GSK461364 | PLK1 | PLK | 33.3 | uM | 9226.001 | 0.0046 | -0.7351 | 2.6569 | |
| HCC1143 | TNBC | Basal A | GSK461364 | PLK1 | PLK | 0.0000853 | uM | 7810.001 | 0.9923 | 0.9830 | 0.9063 | |
| HCC1143 | TNBC | Basal A | GSK461364 | PLK1 | PLK | 0.000427 | uM | 7810.001 | 1.0600 | 1.1327 | 0.9063 | |
| HCC1143 | TNBC | Basal A | GSK461364 | PLK1 | PLK | 0.00213 | uM | 7810.001 | 0.9224 | 0.8293 | 0.9063 | |
| HCC1143 | TNBC | Basal A | GSK461364 | PLK1 | PLK | 0.0107 | uM | 7810.001 | 1.0348 | 1.0769 | 0.9063 | |
| HCC1143 | TNBC | Basal A | GSK461364 | PLK1 | PLK | 0.0533 | uM | 7810.001 | 0.5060 | -0.0568 | 0.9063 | |
| HCC1143 | TNBC | Basal A | GSK461364 | PLK1 | PLK | 0.267 | uM | 7810.001 | 0.3235 | -0.4244 | 0.9063 | |
| HCC1143 | TNBC | Basal A | GSK461364 | PLK1 | PLK | 1.33 | uM | 7810.001 | 0.2867 | -0.4961 | 0.9063 | |
| HCC1143 | TNBC | Basal A | GSK461364 | PLK1 | PLK | 6.67 | uM | 7810.001 | 0.2533 | -0.5605 | 0.9063 |