Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset - HMS LINCS Database

Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)

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Small molecules	Cells	Antibodies

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Cell	Clinical Subtype	Transcriptional Subtype	Small Molecule	Perturbagen Target	Perturbagen Class	Perturbagen Concentration	Perturbagen Conc Unit	Biological Replicate ID	Relative Cell Count	Normalized Growth Rate Inhibition Value	Nominal Division Rate
MDA-MB-157	TNBC	Basal B	GSK1838705A	IGF1R	RTK	13.3	uM	7498.098	0.6642	0.3814	1.1057
MDA-MB-157	TNBC	Basal B	GSK1838705A	IGF1R	RTK	66.7	uM	7498.098	0.0956	-0.7607	1.1057
MDA-MB-175-VII	HR+	Luminal	GSK1838705A	IGF1R	RTK	0.000171	uM	7499.07	0.9488	0.8566	0.7073
MDA-MB-175-VII	HR+	Luminal	GSK1838705A	IGF1R	RTK	0.000853	uM	7499.07	0.9640	0.8990	0.7073
MDA-MB-175-VII	HR+	Luminal	GSK1838705A	IGF1R	RTK	0.00427	uM	7499.07	0.9303	0.8057	0.7073
MDA-MB-175-VII	HR+	Luminal	GSK1838705A	IGF1R	RTK	0.0213	uM	7499.07	0.9563	0.8774	0.7073
MDA-MB-175-VII	HR+	Luminal	GSK1838705A	IGF1R	RTK	0.107	uM	7499.07	0.9577	0.8814	0.7073
MDA-MB-175-VII	HR+	Luminal	GSK1838705A	IGF1R	RTK	0.533	uM	7499.07	0.9409	0.8349	0.7073
MDA-MB-175-VII	HR+	Luminal	GSK1838705A	IGF1R	RTK	2.67	uM	7499.07	0.9008	0.7255	0.7073
MDA-MB-175-VII	HR+	Luminal	GSK1838705A	IGF1R	RTK	13.3	uM	7499.07	0.0442	-0.9757	0.7073
MDA-MB-175-VII	HR+	Luminal	GSK1838705A	IGF1R	RTK	66.7	uM	7499.07	0.0356	-0.9821	0.7073
MDA-MB-175-VII	HR+	Luminal	GSK1838705A	IGF1R	RTK	0.000341	uM	7499.09	0.9913	0.9811	0.9238
MDA-MB-175-VII	HR+	Luminal	GSK1838705A	IGF1R	RTK	0.00171	uM	7499.09	0.9529	0.8983	0.9238
MDA-MB-175-VII	HR+	Luminal	GSK1838705A	IGF1R	RTK	0.00853	uM	7499.09	1.0146	1.0316	0.9238
MDA-MB-175-VII	HR+	Luminal	GSK1838705A	IGF1R	RTK	0.0427	uM	7499.09	1.0053	1.0116	0.9238
MDA-MB-175-VII	HR+	Luminal	GSK1838705A	IGF1R	RTK	0.213	uM	7499.09	0.9165	0.8199	0.9238
MDA-MB-175-VII	HR+	Luminal	GSK1838705A	IGF1R	RTK	1.07	uM	7499.09	0.9579	0.9091	0.9238
MDA-MB-175-VII	HR+	Luminal	GSK1838705A	IGF1R	RTK	5.33	uM	7499.09	0.6911	0.3406	0.9238
MDA-MB-175-VII	HR+	Luminal	GSK1838705A	IGF1R	RTK	26.7	uM	7499.09	0.8433	0.6630	0.9238
MDA-MB-175-VII	HR+	Luminal	GSK1838705A	IGF1R	RTK	133	uM	7499.09	0.5305	0.0070	0.9238
MDA-MB-175-VII	HR+	Luminal	GSK1838705A	IGF1R	RTK	0.000171	uM	7499.098	1.0471	1.1487	0.6421
MDA-MB-175-VII	HR+	Luminal	GSK1838705A	IGF1R	RTK	0.000853	uM	7499.098	0.9951	0.9849	0.6421
MDA-MB-175-VII	HR+	Luminal	GSK1838705A	IGF1R	RTK	0.00427	uM	7499.098	1.0100	1.0312	0.6421
MDA-MB-175-VII	HR+	Luminal	GSK1838705A	IGF1R	RTK	0.0213	uM	7499.098	1.0535	1.1691	0.6421
MDA-MB-175-VII	HR+	Luminal	GSK1838705A	IGF1R	RTK	0.107	uM	7499.098	0.9907	0.9710	0.6421

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HMS LINCS Project

Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)