Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MDA-MB-175-VII | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 0.533 | uM | 7499.098 | 1.0769 | 1.2447 | 0.6421 | |
| MDA-MB-175-VII | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 2.67 | uM | 7499.098 | 0.9941 | 0.9818 | 0.6421 | |
| MDA-MB-175-VII | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 13.3 | uM | 7499.098 | 0.0481 | -0.9823 | 0.6421 | |
| MDA-MB-175-VII | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 66.7 | uM | 7499.098 | 0.0403 | -0.9866 | 0.6421 | |
| MDA-MB-175-VII | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 0.000307 | uM | 7500.071 | 1.0246 | 1.0568 | 0.8688 | |
| MDA-MB-175-VII | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 0.00154 | uM | 7500.071 | 0.9898 | 0.9766 | 0.8688 | |
| MDA-MB-175-VII | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 0.00768 | uM | 7500.071 | 0.9377 | 0.8573 | 0.8688 | |
| MDA-MB-175-VII | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 0.0384 | uM | 7500.071 | 0.9537 | 0.8938 | 0.8688 | |
| MDA-MB-175-VII | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 0.192 | uM | 7500.071 | 0.9747 | 0.9419 | 0.8688 | |
| MDA-MB-175-VII | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 0.96 | uM | 7500.071 | 1.0034 | 1.0078 | 0.8688 | |
| MDA-MB-175-VII | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 4.8 | uM | 7500.071 | 0.8250 | 0.6028 | 0.8688 | |
| MDA-MB-175-VII | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 24 | uM | 7500.071 | 0.0223 | -0.9749 | 0.8688 | |
| MDA-MB-175-VII | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 120 | uM | 7500.071 | 0.0866 | -0.8803 | 0.8688 | |
| MDA-MB-175-VII | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 0.000341 | uM | 7500.091 | 1.0009 | 1.0027 | 0.6237 | |
| MDA-MB-175-VII | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 0.00171 | uM | 7500.091 | 1.0241 | 1.0777 | 0.6237 | |
| MDA-MB-175-VII | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 0.00853 | uM | 7500.091 | 0.9854 | 0.9533 | 0.6237 | |
| MDA-MB-175-VII | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 0.0427 | uM | 7500.091 | 1.1763 | 1.5948 | 0.6237 | |
| MDA-MB-175-VII | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 0.213 | uM | 7500.091 | 1.0396 | 1.1286 | 0.6237 | |
| MDA-MB-175-VII | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 1.07 | uM | 7500.091 | 0.9316 | 0.7852 | 0.6237 | |
| MDA-MB-175-VII | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 5.33 | uM | 7500.091 | 1.0730 | 1.2393 | 0.6237 | |
| MDA-MB-175-VII | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 26.7 | uM | 7500.091 | 0.9783 | 0.9310 | 0.6237 | |
| MDA-MB-175-VII | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 133 | uM | 7500.091 | 0.2778 | -0.7435 | 0.6237 | |
| MDA-MB-175-VII | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 0.000171 | uM | 7500.098 | 1.0409 | 1.1059 | 0.7767 | |
| MDA-MB-175-VII | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 0.000853 | uM | 7500.098 | 1.0146 | 1.0378 | 0.7767 | |
| MDA-MB-175-VII | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 0.00427 | uM | 7500.098 | 0.9885 | 0.9703 | 0.7767 |