Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MB 157 | Unknown | Unknown | GSK1838705A | IGF1R | RTK | 0.000341 | uM | 7482.091 | 0.9658 | 0.9644 | 1.9368 | |
| MB 157 | Unknown | Unknown | GSK1838705A | IGF1R | RTK | 0.00171 | uM | 7482.091 | 0.9200 | 0.9157 | 1.9368 | |
| MB 157 | Unknown | Unknown | GSK1838705A | IGF1R | RTK | 0.00853 | uM | 7482.091 | 1.0266 | 1.0273 | 1.9368 | |
| MB 157 | Unknown | Unknown | GSK1838705A | IGF1R | RTK | 0.0427 | uM | 7482.091 | 1.0500 | 1.0510 | 1.9368 | |
| MB 157 | Unknown | Unknown | GSK1838705A | IGF1R | RTK | 0.213 | uM | 7482.091 | 0.7115 | 0.6777 | 1.9368 | |
| MB 157 | Unknown | Unknown | GSK1838705A | IGF1R | RTK | 1.07 | uM | 7482.091 | 0.5553 | 0.4761 | 1.9368 | |
| MB 157 | Unknown | Unknown | GSK1838705A | IGF1R | RTK | 5.33 | uM | 7482.091 | 0.7267 | 0.6961 | 1.9368 | |
| MB 157 | Unknown | Unknown | GSK1838705A | IGF1R | RTK | 26.7 | uM | 7482.091 | 0.5714 | 0.4980 | 1.9368 | |
| MB 157 | Unknown | Unknown | GSK1838705A | IGF1R | RTK | 133 | uM | 7482.091 | 0.8082 | 0.7917 | 1.9368 | |
| MB 157 | Unknown | Unknown | GSK1838705A | IGF1R | RTK | 0.000171 | uM | 7482.098 | 0.9694 | 0.9725 | 2.2478 | |
| MB 157 | Unknown | Unknown | GSK1838705A | IGF1R | RTK | 0.000853 | uM | 7482.098 | 0.9477 | 0.9527 | 2.2478 | |
| MB 157 | Unknown | Unknown | GSK1838705A | IGF1R | RTK | 0.00427 | uM | 7482.098 | 0.9724 | 0.9752 | 2.2478 | |
| MB 157 | Unknown | Unknown | GSK1838705A | IGF1R | RTK | 0.0213 | uM | 7482.098 | 0.9263 | 0.9330 | 2.2478 | |
| MB 157 | Unknown | Unknown | GSK1838705A | IGF1R | RTK | 0.107 | uM | 7482.098 | 0.9363 | 0.9423 | 2.2478 | |
| MB 157 | Unknown | Unknown | GSK1838705A | IGF1R | RTK | 0.533 | uM | 7482.098 | 0.8676 | 0.8775 | 2.2478 | |
| MB 157 | Unknown | Unknown | GSK1838705A | IGF1R | RTK | 2.67 | uM | 7482.098 | 0.7179 | 0.7258 | 2.2478 | |
| MB 157 | Unknown | Unknown | GSK1838705A | IGF1R | RTK | 13.3 | uM | 7482.098 | 0.5667 | 0.5534 | 2.2478 | |
| MB 157 | Unknown | Unknown | GSK1838705A | IGF1R | RTK | 66.7 | uM | 7482.098 | 0.0158 | -0.6844 | 2.2478 | |
| MCF 10A | NM | Basal B | GSK1838705A | IGF1R | RTK | 0.000307 | uM | 7483.071 | 0.9587 | 0.9764 | 3.5590 | |
| MCF 10A | NM | Basal B | GSK1838705A | IGF1R | RTK | 0.00154 | uM | 7483.071 | 0.9715 | 0.9838 | 3.5590 | |
| MCF 10A | NM | Basal B | GSK1838705A | IGF1R | RTK | 0.00768 | uM | 7483.071 | 0.9674 | 0.9815 | 3.5590 | |
| MCF 10A | NM | Basal B | GSK1838705A | IGF1R | RTK | 0.0384 | uM | 7483.071 | 0.9365 | 0.9635 | 3.5590 | |
| MCF 10A | NM | Basal B | GSK1838705A | IGF1R | RTK | 0.192 | uM | 7483.071 | 0.9200 | 0.9537 | 3.5590 | |
| MCF 10A | NM | Basal B | GSK1838705A | IGF1R | RTK | 0.96 | uM | 7483.071 | 0.6952 | 0.8058 | 3.5590 | |
| MCF 10A | NM | Basal B | GSK1838705A | IGF1R | RTK | 4.8 | uM | 7483.071 | 0.6364 | 0.7615 | 3.5590 |