Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MDA-MB-157 | TNBC | Basal B | GSK1838705A | IGF1R | RTK | 0.000171 | uM | 7496.098 | 0.9908 | 0.9797 | 0.9037 | |
| MDA-MB-157 | TNBC | Basal B | GSK1838705A | IGF1R | RTK | 0.000853 | uM | 7496.098 | 1.0345 | 1.0765 | 0.9037 | |
| MDA-MB-157 | TNBC | Basal B | GSK1838705A | IGF1R | RTK | 0.00427 | uM | 7496.098 | 1.0156 | 1.0347 | 0.9037 | |
| MDA-MB-157 | TNBC | Basal B | GSK1838705A | IGF1R | RTK | 0.0213 | uM | 7496.098 | 0.9672 | 0.9276 | 0.9037 | |
| MDA-MB-157 | TNBC | Basal B | GSK1838705A | IGF1R | RTK | 0.107 | uM | 7496.098 | 0.9941 | 0.9870 | 0.9037 | |
| MDA-MB-157 | TNBC | Basal B | GSK1838705A | IGF1R | RTK | 0.533 | uM | 7496.098 | 0.9378 | 0.8627 | 0.9037 | |
| MDA-MB-157 | TNBC | Basal B | GSK1838705A | IGF1R | RTK | 2.67 | uM | 7496.098 | 0.9282 | 0.8418 | 0.9037 | |
| MDA-MB-157 | TNBC | Basal B | GSK1838705A | IGF1R | RTK | 13.3 | uM | 7496.098 | 0.1298 | -0.7911 | 0.9037 | |
| MDA-MB-157 | TNBC | Basal B | GSK1838705A | IGF1R | RTK | 66.7 | uM | 7496.098 | 0.5448 | 0.0214 | 0.9037 | |
| MDA-MB-157 | TNBC | Basal B | GSK1838705A | IGF1R | RTK | 0.000341 | uM | 7498.091 | 1.0407 | 1.0709 | 1.1445 | |
| MDA-MB-157 | TNBC | Basal B | GSK1838705A | IGF1R | RTK | 0.00171 | uM | 7498.091 | 0.9678 | 0.9435 | 1.1445 | |
| MDA-MB-157 | TNBC | Basal B | GSK1838705A | IGF1R | RTK | 0.00853 | uM | 7498.091 | 1.0091 | 1.0159 | 1.1445 | |
| MDA-MB-157 | TNBC | Basal B | GSK1838705A | IGF1R | RTK | 0.0427 | uM | 7498.091 | 1.0427 | 1.0744 | 1.1445 | |
| MDA-MB-157 | TNBC | Basal B | GSK1838705A | IGF1R | RTK | 0.213 | uM | 7498.091 | 1.0274 | 1.0478 | 1.1445 | |
| MDA-MB-157 | TNBC | Basal B | GSK1838705A | IGF1R | RTK | 1.07 | uM | 7498.091 | 0.9288 | 0.8751 | 1.1445 | |
| MDA-MB-157 | TNBC | Basal B | GSK1838705A | IGF1R | RTK | 5.33 | uM | 7498.091 | 0.9183 | 0.8564 | 1.1445 | |
| MDA-MB-157 | TNBC | Basal B | GSK1838705A | IGF1R | RTK | 26.7 | uM | 7498.091 | 0.0728 | -0.7974 | 1.1445 | |
| MDA-MB-157 | TNBC | Basal B | GSK1838705A | IGF1R | RTK | 133 | uM | 7498.091 | 0.0946 | -0.7451 | 1.1445 | |
| MDA-MB-157 | TNBC | Basal B | GSK1838705A | IGF1R | RTK | 0.000171 | uM | 7498.098 | 0.9961 | 0.9929 | 1.1057 | |
| MDA-MB-157 | TNBC | Basal B | GSK1838705A | IGF1R | RTK | 0.000853 | uM | 7498.098 | 0.9224 | 0.8591 | 1.1057 | |
| MDA-MB-157 | TNBC | Basal B | GSK1838705A | IGF1R | RTK | 0.00427 | uM | 7498.098 | 1.0055 | 1.0099 | 1.1057 | |
| MDA-MB-157 | TNBC | Basal B | GSK1838705A | IGF1R | RTK | 0.0213 | uM | 7498.098 | 0.9434 | 0.8973 | 1.1057 | |
| MDA-MB-157 | TNBC | Basal B | GSK1838705A | IGF1R | RTK | 0.107 | uM | 7498.098 | 0.9857 | 0.9742 | 1.1057 | |
| MDA-MB-157 | TNBC | Basal B | GSK1838705A | IGF1R | RTK | 0.533 | uM | 7498.098 | 0.9320 | 0.8765 | 1.1057 | |
| MDA-MB-157 | TNBC | Basal B | GSK1838705A | IGF1R | RTK | 2.67 | uM | 7498.098 | 0.8733 | 0.7693 | 1.1057 |