Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC1143 | TNBC | Basal A | 5-FU | TYMS | TYMS | 3840 | uM | 7809.017 | 0.4559 | 0.2797 | 1.7591 | |
| HCC1143 | TNBC | Basal A | 5-FU | TYMS | TYMS | 19200 | uM | 7809.017 | 0.5203 | 0.3795 | 1.7591 | |
| HCC1143 | TNBC | Basal A | 5-FU | TYMS | TYMS | 0.0492 | uM | 7810.017 | 0.9951 | 0.9890 | 0.8986 | |
| HCC1143 | TNBC | Basal A | 5-FU | TYMS | TYMS | 0.246 | uM | 7810.017 | 1.0958 | 1.2143 | 0.8986 | |
| HCC1143 | TNBC | Basal A | 5-FU | TYMS | TYMS | 1.23 | uM | 7810.017 | 1.0470 | 1.1049 | 0.8986 | |
| HCC1143 | TNBC | Basal A | 5-FU | TYMS | TYMS | 6.15 | uM | 7810.017 | 0.9801 | 0.9558 | 0.8986 | |
| HCC1143 | TNBC | Basal A | 5-FU | TYMS | TYMS | 30.7 | uM | 7810.017 | 0.7792 | 0.5152 | 0.8986 | |
| HCC1143 | TNBC | Basal A | 5-FU | TYMS | TYMS | 154 | uM | 7810.017 | 0.6881 | 0.3194 | 0.8986 | |
| HCC1143 | TNBC | Basal A | 5-FU | TYMS | TYMS | 769 | uM | 7810.017 | 0.6155 | 0.1655 | 0.8986 | |
| HCC1143 | TNBC | Basal A | 5-FU | TYMS | TYMS | 3840 | uM | 7810.017 | 0.4892 | -0.0975 | 0.8986 | |
| HCC1143 | TNBC | Basal A | 5-FU | TYMS | TYMS | 19200 | uM | 7810.017 | 0.3757 | -0.3272 | 0.8986 | |
| HCC1187 | TNBC | Basal A | 5-FU | TYMS | TYMS | 0.0492 | uM | 7811.017 | 1.0311 | 1.1772 | 0.3604 | |
| HCC1187 | TNBC | Basal A | 5-FU | TYMS | TYMS | 0.246 | uM | 7811.017 | 0.9175 | 0.5750 | 0.3604 | |
| HCC1187 | TNBC | Basal A | 5-FU | TYMS | TYMS | 1.23 | uM | 7811.017 | 0.8946 | 0.4685 | 0.3604 | |
| HCC1187 | TNBC | Basal A | 5-FU | TYMS | TYMS | 6.15 | uM | 7811.017 | 0.9472 | 0.7207 | 0.3604 | |
| HCC1187 | TNBC | Basal A | 5-FU | TYMS | TYMS | 30.7 | uM | 7811.017 | 0.8853 | 0.4263 | 0.3604 | |
| HCC1187 | TNBC | Basal A | 5-FU | TYMS | TYMS | 154 | uM | 7811.017 | 0.5698 | -0.5800 | 0.3604 | |
| HCC1187 | TNBC | Basal A | 5-FU | TYMS | TYMS | 769 | uM | 7811.017 | 0.3521 | -0.8895 | 0.3604 | |
| HCC1187 | TNBC | Basal A | 5-FU | TYMS | TYMS | 3840 | uM | 7811.017 | 0.0484 | -0.9996 | 0.3604 | |
| HCC1187 | TNBC | Basal A | 5-FU | TYMS | TYMS | 19200 | uM | 7811.017 | 0.0412 | -0.9997 | 0.3604 | |
| HCC1187 | TNBC | Basal A | 5-FU | TYMS | TYMS | 0.0492 | uM | 7812.017 | 1.0643 | 1.1127 | 1.1362 | |
| HCC1187 | TNBC | Basal A | 5-FU | TYMS | TYMS | 0.246 | uM | 7812.017 | 1.2322 | 1.4035 | 1.1362 | |
| HCC1187 | TNBC | Basal A | 5-FU | TYMS | TYMS | 1.23 | uM | 7812.017 | 1.1008 | 1.1764 | 1.1362 | |
| HCC1187 | TNBC | Basal A | 5-FU | TYMS | TYMS | 6.15 | uM | 7812.017 | 1.0138 | 1.0242 | 1.1362 | |
| HCC1187 | TNBC | Basal A | 5-FU | TYMS | TYMS | 30.7 | uM | 7812.017 | 1.0415 | 1.0729 | 1.1362 |