Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HBL-100 | Unknown | Unknown | 5-FU | TYMS | TYMS | 0.0492 | uM | 7807.017 | 1.0182 | 1.0164 | 2.2007 | |
| HBL-100 | Unknown | Unknown | 5-FU | TYMS | TYMS | 0.246 | uM | 7807.017 | 1.0227 | 1.0205 | 2.2007 | |
| HBL-100 | Unknown | Unknown | 5-FU | TYMS | TYMS | 1.23 | uM | 7807.017 | 0.9530 | 0.9568 | 2.2007 | |
| HBL-100 | Unknown | Unknown | 5-FU | TYMS | TYMS | 6.15 | uM | 7807.017 | 0.8795 | 0.8867 | 2.2007 | |
| HBL-100 | Unknown | Unknown | 5-FU | TYMS | TYMS | 30.7 | uM | 7807.017 | 0.6371 | 0.6296 | 2.2007 | |
| HBL-100 | Unknown | Unknown | 5-FU | TYMS | TYMS | 154 | uM | 7807.017 | 0.4785 | 0.4308 | 2.2007 | |
| HBL-100 | Unknown | Unknown | 5-FU | TYMS | TYMS | 769 | uM | 7807.017 | 0.3621 | 0.2606 | 2.2007 | |
| HBL-100 | Unknown | Unknown | 5-FU | TYMS | TYMS | 3840 | uM | 7807.017 | 0.2547 | 0.0743 | 2.2007 | |
| HBL-100 | Unknown | Unknown | 5-FU | TYMS | TYMS | 19200 | uM | 7807.017 | 0.1894 | -0.0609 | 2.2007 | |
| HBL-100 | Unknown | Unknown | 5-FU | TYMS | TYMS | 0.0492 | uM | 7808.017 | 0.8959 | 0.9111 | 2.4168 | |
| HBL-100 | Unknown | Unknown | 5-FU | TYMS | TYMS | 0.246 | uM | 7808.017 | 1.1278 | 1.1021 | 2.4168 | |
| HBL-100 | Unknown | Unknown | 5-FU | TYMS | TYMS | 1.23 | uM | 7808.017 | 0.8781 | 0.8953 | 2.4168 | |
| HBL-100 | Unknown | Unknown | 5-FU | TYMS | TYMS | 6.15 | uM | 7808.017 | 0.9268 | 0.9381 | 2.4168 | |
| HBL-100 | Unknown | Unknown | 5-FU | TYMS | TYMS | 30.7 | uM | 7808.017 | 0.6608 | 0.6849 | 2.4168 | |
| HBL-100 | Unknown | Unknown | 5-FU | TYMS | TYMS | 154 | uM | 7808.017 | 0.4802 | 0.4764 | 2.4168 | |
| HBL-100 | Unknown | Unknown | 5-FU | TYMS | TYMS | 769 | uM | 7808.017 | 0.3278 | 0.2607 | 2.4168 | |
| HBL-100 | Unknown | Unknown | 5-FU | TYMS | TYMS | 3840 | uM | 7808.017 | 0.2303 | 0.0894 | 2.4168 | |
| HBL-100 | Unknown | Unknown | 5-FU | TYMS | TYMS | 19200 | uM | 7808.017 | 0.1495 | -0.0890 | 2.4168 | |
| HCC1143 | TNBC | Basal A | 5-FU | TYMS | TYMS | 0.0492 | uM | 7809.017 | 0.9061 | 0.8910 | 1.7591 | |
| HCC1143 | TNBC | Basal A | 5-FU | TYMS | TYMS | 0.246 | uM | 7809.017 | 0.9739 | 0.9701 | 1.7591 | |
| HCC1143 | TNBC | Basal A | 5-FU | TYMS | TYMS | 1.23 | uM | 7809.017 | 0.8631 | 0.8394 | 1.7591 | |
| HCC1143 | TNBC | Basal A | 5-FU | TYMS | TYMS | 6.15 | uM | 7809.017 | 0.9074 | 0.8925 | 1.7591 | |
| HCC1143 | TNBC | Basal A | 5-FU | TYMS | TYMS | 30.7 | uM | 7809.017 | 0.8227 | 0.7900 | 1.7591 | |
| HCC1143 | TNBC | Basal A | 5-FU | TYMS | TYMS | 154 | uM | 7809.017 | 0.7274 | 0.6689 | 1.7591 | |
| HCC1143 | TNBC | Basal A | 5-FU | TYMS | TYMS | 769 | uM | 7809.017 | 0.5709 | 0.4542 | 1.7591 |