Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC1187 | TNBC | Basal A | 5-FU | TYMS | TYMS | 154 | uM | 7812.017 | 0.9060 | 0.8336 | 1.1362 | |
| HCC1187 | TNBC | Basal A | 5-FU | TYMS | TYMS | 769 | uM | 7812.017 | 0.7141 | 0.4871 | 1.1362 | |
| HCC1187 | TNBC | Basal A | 5-FU | TYMS | TYMS | 3840 | uM | 7812.017 | 0.3413 | -0.2236 | 1.1362 | |
| HCC1187 | TNBC | Basal A | 5-FU | TYMS | TYMS | 19200 | uM | 7812.017 | 0.0615 | -0.8283 | 1.1362 | |
| HCC1395 | TNBC | Basal B | 5-FU | TYMS | TYMS | 0.0492 | uM | 7813.017 | 1.0603 | 1.1395 | 0.8685 | |
| HCC1395 | TNBC | Basal B | 5-FU | TYMS | TYMS | 0.246 | uM | 7813.017 | 1.0722 | 1.1672 | 0.8685 | |
| HCC1395 | TNBC | Basal B | 5-FU | TYMS | TYMS | 1.23 | uM | 7813.017 | 1.0848 | 1.1966 | 0.8685 | |
| HCC1395 | TNBC | Basal B | 5-FU | TYMS | TYMS | 6.15 | uM | 7813.017 | 1.1120 | 1.2600 | 0.8685 | |
| HCC1395 | TNBC | Basal B | 5-FU | TYMS | TYMS | 30.7 | uM | 7813.017 | 1.0404 | 1.0934 | 0.8685 | |
| HCC1395 | TNBC | Basal B | 5-FU | TYMS | TYMS | 154 | uM | 7813.017 | 0.9602 | 0.9087 | 0.8685 | |
| HCC1395 | TNBC | Basal B | 5-FU | TYMS | TYMS | 769 | uM | 7813.017 | 0.8476 | 0.6533 | 0.8685 | |
| HCC1395 | TNBC | Basal B | 5-FU | TYMS | TYMS | 3840 | uM | 7813.017 | 0.5461 | -0.0035 | 0.8685 | |
| HCC1395 | TNBC | Basal B | 5-FU | TYMS | TYMS | 19200 | uM | 7813.017 | 0.3870 | -0.3296 | 0.8685 | |
| HCC1395 | TNBC | Basal B | 5-FU | TYMS | TYMS | 0.0492 | uM | 7814.017 | 1.0397 | 1.0966 | 0.8254 | |
| HCC1395 | TNBC | Basal B | 5-FU | TYMS | TYMS | 0.246 | uM | 7814.017 | 1.0326 | 1.0792 | 0.8254 | |
| HCC1395 | TNBC | Basal B | 5-FU | TYMS | TYMS | 1.23 | uM | 7814.017 | 1.0139 | 1.0337 | 0.8254 | |
| HCC1395 | TNBC | Basal B | 5-FU | TYMS | TYMS | 6.15 | uM | 7814.017 | 0.9882 | 0.9715 | 0.8254 | |
| HCC1395 | TNBC | Basal B | 5-FU | TYMS | TYMS | 30.7 | uM | 7814.017 | 0.8849 | 0.7245 | 0.8254 | |
| HCC1395 | TNBC | Basal B | 5-FU | TYMS | TYMS | 154 | uM | 7814.017 | 0.8756 | 0.7027 | 0.8254 | |
| HCC1395 | TNBC | Basal B | 5-FU | TYMS | TYMS | 769 | uM | 7814.017 | 0.7080 | 0.3162 | 0.8254 | |
| HCC1395 | TNBC | Basal B | 5-FU | TYMS | TYMS | 3840 | uM | 7814.017 | 0.4661 | -0.2069 | 0.8254 | |
| HCC1395 | TNBC | Basal B | 5-FU | TYMS | TYMS | 19200 | uM | 7814.017 | 0.3135 | -0.5095 | 0.8254 | |
| HCC1395 | TNBC | Basal B | 5-FU | TYMS | TYMS | 0.0492 | uM | 7816.017 | 0.9893 | 0.9826 | 1.2318 | |
| HCC1395 | TNBC | Basal B | 5-FU | TYMS | TYMS | 0.246 | uM | 7816.017 | 1.0029 | 1.0046 | 1.2318 | |
| HCC1395 | TNBC | Basal B | 5-FU | TYMS | TYMS | 1.23 | uM | 7816.017 | 1.0110 | 1.0179 | 1.2318 |